General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 3486 |
Name | IGFBP3 |
Synonymous | BP-53|IBP3;insulin-like growth factor binding protein 3;IGFBP3;insulin-like growth factor binding protein 3 |
Definition | IBP-3|IGF-binding protein 3|IGFBP-3|acid stable subunit of the 140 K IGF complex|binding protein 29|binding protein 53|growth hormone-dependent binding protein|insulin-like growth factor-binding protein 3 |
Position | 7p12.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
IGFALS | REACTOME; |
interacts with |
ADAM12 | BIOGRID; |
interacts with |
ADAM12 | HPRD; |
interacts with |
CAV1 | HPRD; |
interacts with |
CD44 | BIOGRID; |
interacts with |
CD44 | HPRD; |
interacts with |
COL1A1 | BIOGRID; |
interacts with |
COL1A1 | HPRD; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CTSD | HPRD; |
interacts with |
CTSG | HPRD; |
interacts with |
CTSL1 | HPRD; |
interacts with |
F2 | HPRD; |
interacts with |
FN1 | BIOGRID; |
interacts with |
GPI | HPRD; |
interacts with |
GTF3C1 | BIOGRID; |
interacts with |
GTF3C1 | HPRD; |
interacts with |
GTF3C1 | MINT; |
interacts with |
IGF1 | BIOGRID; |
interacts with |
IGF1R | BIOGRID; |
interacts with |
IGF1R | HPRD; |
interacts with |
Igf2 | BIOGRID; |
interacts with |
IGF2 | BIOGRID; |
interacts with |
IGF2 | HPRD; |
interacts with |
IGFALS | BIOGRID; |
interacts with |
IGFALS | HPRD; |
interacts with |
IGFBP2 | HPRD; |
interacts with |
IGFBP5 | HPRD; |
interacts with |
KLKB1 | HPRD; |
interacts with |
KPNB1 | HPRD; |
interacts with |
Ltbp1 | BIOGRID; |
interacts with |
LTBP1 | HPRD; |
interacts with |
MMP2 | HPRD; |
interacts with |
MMP3 | HPRD; |
interacts with |
MT-RNR2 | HPRD; |
interacts with |
PAPPA2 | BIOGRID; |
interacts with |
PLG | BIOGRID; |
interacts with |
PLG | HPRD; |
interacts with |
POLA2 | BIOGRID; |
interacts with |
POLA2 | HPRD; |
interacts with |
POLA2 | MINT; |
interacts with |
RXRA | BIOGRID; |
interacts with |
TF | BIOGRID; |
interacts with |
VTN | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TP53 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
IGFALS | REACTOME; |
reacts with |
IGFBP3 | REACTOME; |
state change |
CTSG | REACTOME; |
state change |
F2 | REACTOME; |
state change |
IGFBP3 | REACTOME; |
state change |
KLK3 | REACTOME; |
state change |
PLG | REACTOME; |