| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4851 |
Name | NOTCH1 |
Synonymous | AOS5|AOVD1|TAN1|hN1;notch 1;NOTCH1;notch 1 |
Definition | Notch homolog 1, translocation-associated|neurogenic locus notch homolog protein 1|translocation-associated notch protein TAN-1 |
Position | 9q34.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
in same component |
CNTN1 | NCI_NATURE; |
in same component |
CNTN6 | NCI_NATURE; |
in same component |
DLK1 | NCI_NATURE; |
in same component |
DLL1 | NCI_NATURE; |
in same component |
DNER | NCI_NATURE; |
in same component |
DTX1 | NCI_NATURE; |
in same component |
DVL1 | NCI_NATURE; |
in same component |
EP300 | NCI_NATURE; |
in same component |
JAG1 | NCI_NATURE; |
in same component |
JAG2 | NCI_NATURE; |
in same component |
RBPJ | NCI_NATURE; |
in same component |
YY1 | NCI_NATURE; |
interacts with |
ADAM17 | HPRD; |
interacts with |
AKT1 | BIOGRID; |
interacts with |
APBA1 | HPRD; |
interacts with |
BLOC1S1 | HPRD; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CNTN1 | BIOGRID; |
interacts with |
CNTN1 | HPRD; |
interacts with |
CTNNB1 | BIOGRID; |
interacts with |
DLL1 | BIOGRID; |
interacts with |
DLL1 | HPRD; |
interacts with |
DLL4 | HPRD; |
interacts with |
DTX1 | BIOGRID; |
interacts with |
DTX1 | HPRD; |
interacts with |
DTX2 | HPRD; |
interacts with |
EP300 | BIOGRID; |
interacts with |
EP300 | HPRD; |
interacts with |
FBXW7 | BIOGRID; |
interacts with |
FBXW7 | HPRD; |
interacts with |
FURIN | HPRD; |
interacts with |
GFI1B | HPRD; |
interacts with |
GFI1B | MINT; |
interacts with |
GSK3B | BIOGRID; |
interacts with |
GSK3B | HPRD; |
interacts with |
Itch | BIOGRID; |
interacts with |
ITCH | BIOGRID; |
interacts with |
ITCH | HPRD; |
interacts with |
JAG1 | BIOGRID; |
interacts with |
JAG2 | BIOGRID; |
interacts with |
JAG2 | HPRD; |
interacts with |
KAT2A | HPRD; |
interacts with |
KAT2B | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LEF1 | BIOGRID; |
interacts with |
LFNG | HPRD; |
interacts with |
MAML1 | BIOGRID; |
interacts with |
MAML1 | HPRD; |
interacts with |
MAML3 | BIOGRID; |
interacts with |
MAML3 | HPRD; |
interacts with |
MEF2C | HPRD; |
interacts with |
MFNG | HPRD; |
interacts with |
NFKB1 | BIOGRID; |
interacts with |
NFKB1 | HPRD; |
interacts with |
NFKB1 | MINT; |
interacts with |
NOV | BIOGRID; |
interacts with |
NOV | HPRD; |
interacts with |
NUMBL | HPRD; |
interacts with |
NUMB | BIOGRID; |
interacts with |
NUMB | HPRD; |
interacts with |
PIK3CA | BIOGRID; |
interacts with |
POFUT1 | HPRD; |
interacts with |
PSEN1 | BIOGRID; |
interacts with |
PSEN1 | HPRD; |
interacts with |
PSEN2 | HPRD; |
interacts with |
RBPJ | BIOGRID; |
interacts with |
RBPJ | HPRD; |
interacts with |
RELA | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
REL | HPRD; |
interacts with |
REL | MINT; |
interacts with |
SNW1 | BIOGRID; |
interacts with |
SNW1 | HPRD; |
interacts with |
WDR12 | HPRD; |
interacts with |
XIAP | HPRD; |
interacts with |
XIAP | MINT; |
interacts with |
XRCC6 | BIOGRID; |
interacts with |
XRCC6 | HPRD; |
interacts with |
XRCC6 | MINT; |
interacts with |
YY1 | BIOGRID; |
interacts with |
YY1 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for NOTCH1 | ||
Signaling Interaction [Top] | ||
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
CNTN1 | NCI_NATURE; |
reacts with |
CNTN6 | NCI_NATURE; |
reacts with |
CTBP1 | NCI_NATURE; |
reacts with |
DLK1 | NCI_NATURE; |
reacts with |
DLL1 | NCI_NATURE; |
reacts with |
DNER | NCI_NATURE; |
reacts with |
DTX1 | NCI_NATURE; |
reacts with |
DVL1 | NCI_NATURE; |
reacts with |
EP300 | NCI_NATURE; |
reacts with |
HDAC1 | NCI_NATURE; |
reacts with |
HES1 | NCI_NATURE; |
reacts with |
HEY1 | NCI_NATURE; |
reacts with |
JAG1 | NCI_NATURE; |
reacts with |
JAG2 | NCI_NATURE; |
reacts with |
KDM1A | NCI_NATURE; |
reacts with |
NOTCH1 | NCI_NATURE; |
reacts with |
NOTCH1 | REACTOME; |
reacts with |
RBBP8 | NCI_NATURE; |
reacts with |
RBPJ | NCI_NATURE; |
reacts with |
SPEN | NCI_NATURE; |
reacts with |
YY1 | NCI_NATURE; |
state change |
ADAM10 | NCI_NATURE; |
state change |
APH1A | NCI_NATURE; |
state change |
APH1B | NCI_NATURE; |
state change |
DLL3 | NCI_NATURE; |
state change |
DNM1 | NCI_NATURE; |
state change |
EPS15 | NCI_NATURE; |
state change |
FURIN | NCI_NATURE; |
state change |
ITCH | NCI_NATURE; |
state change |
MFAP5 | NCI_NATURE; |
state change |
NCSTN | NCI_NATURE; |
state change |
NUMB | NCI_NATURE; |
state change |
PSEN1 | NCI_NATURE; |
state change |
PSENEN | NCI_NATURE; |