General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 5515 |
Name | PPP2CA |
Synonymous | PP2Ac|PP2CA|PP2Calpha|RP-C;protein phosphatase 2, catalytic subunit, alpha isozyme;PPP2CA;protein phosphatase 2, catalytic subunit, alpha isozyme |
Definition | PP2A-alpha|protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform|protein phosphatase 2A catalytic subunit, alpha isoform|replication protein C|serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform|serine/threonine-prote |
Position | 5q31.1 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
AXIN1 | NCI_NATURE; |
in same component |
CASC3 | REACTOME; |
in same component |
CCNG1 | NCI_NATURE; |
in same component |
EIF4A3 | REACTOME; |
in same component |
EIF4G1 | REACTOME; |
in same component |
ETF1 | REACTOME; |
in same component |
GSK3B | NCI_NATURE; |
in same component |
GSPT2 | REACTOME; |
in same component |
MAGOH | REACTOME; |
in same component |
NCBP1 | REACTOME; |
in same component |
NCBP2 | REACTOME; |
in same component |
PABPC1 | REACTOME; |
in same component |
PIN1 | NCI_NATURE; |
in same component |
PPP2R1A | NCI_NATURE; |
in same component |
PPP2R1A | REACTOME; |
in same component |
PPP2R2A | NCI_NATURE; |
in same component |
PPP2R2A | REACTOME; |
in same component |
PPP2R2B | NCI_NATURE; |
in same component |
PPP2R3B | NCI_NATURE; |
in same component |
PPP2R4 | NCI_NATURE; |
in same component |
PPP2R5A | NCI_NATURE; |
in same component |
RBM8A | REACTOME; |
in same component |
RNPS1 | REACTOME; |
in same component |
RPL10 | REACTOME; |
in same component |
RPL12 | REACTOME; |
in same component |
RPL13A | REACTOME; |
in same component |
RPL13 | REACTOME; |
in same component |
RPL14 | REACTOME; |
in same component |
RPL17 | REACTOME; |
in same component |
RPL18A | REACTOME; |
in same component |
RPL18 | REACTOME; |
in same component |
RPL21 | REACTOME; |
in same component |
RPL22 | REACTOME; |
in same component |
RPL26L1 | REACTOME; |
in same component |
RPL27A | REACTOME; |
in same component |
RPL28 | REACTOME; |
in same component |
RPL29 | REACTOME; |
in same component |
RPL34 | REACTOME; |
in same component |
RPL35A | REACTOME; |
in same component |
RPL35 | REACTOME; |
in same component |
RPL36 | REACTOME; |
in same component |
RPL3L | REACTOME; |
in same component |
RPL3 | REACTOME; |
in same component |
RPL4 | REACTOME; |
in same component |
RPL5 | REACTOME; |
in same component |
RPL6 | REACTOME; |
in same component |
RPL7 | REACTOME; |
in same component |
RPL9 | REACTOME; |
in same component |
RPLP0 | REACTOME; |
in same component |
RPLP1 | REACTOME; |
in same component |
RPLP2 | REACTOME; |
in same component |
RPS10 | REACTOME; |
in same component |
RPS12 | REACTOME; |
in same component |
RPS17 | REACTOME; |
in same component |
RPS19 | REACTOME; |
in same component |
RPS21 | REACTOME; |
in same component |
RPS27 | REACTOME; |
in same component |
RPS2 | REACTOME; |
in same component |
RPS3 | REACTOME; |
in same component |
RPS4Y1 | REACTOME; |
in same component |
RPS5 | REACTOME; |
in same component |
RPS9 | REACTOME; |
in same component |
RPSA | REACTOME; |
in same component |
SMG5 | REACTOME; |
in same component |
SMG6 | REACTOME; |
in same component |
SMG7 | REACTOME; |
in same component |
SNCA | IMID; |
in same component |
UPF1 | REACTOME; |
in same component |
UPF2 | REACTOME; |
interacts with |
ACTL6A | INTACT; |
interacts with |
ADNP | INTACT; |
interacts with |
AHDC1 | INTACT; |
interacts with |
AKT1 | HPRD; |
interacts with |
AKT1 | MINT; |
interacts with |
APC | HPRD; |
interacts with |
ARL2 | BIOGRID; |
interacts with |
AURKB | INTACT; |
interacts with |
AXIN1 | CELL_MAP; |
interacts with |
AXIN1 | HPRD; |
interacts with |
AXIN1 | MINT; |
interacts with |
BCL2 | BIOGRID; |
interacts with |
BCL2 | HPRD; |
interacts with |
BCL2 | MINT; |
interacts with |
BCL7A | INTACT; |
interacts with |
BEST1 | BIOGRID; |
interacts with |
BMPR1B | HPRD; |
interacts with |
CAD | HPRD; |
interacts with |
CBX1 | INTACT; |
interacts with |
CBX3 | INTACT; |
interacts with |
CBX5 | INTACT; |
interacts with |
CCNG1 | HPRD; |
interacts with |
CCNG2 | BIOGRID; |
interacts with |
CCT2 | BIOGRID; |
interacts with |
CCT3 | BIOGRID; |
interacts with |
CCT4 | BIOGRID; |
interacts with |
CCT5 | BIOGRID; |
interacts with |
CCT6A | BIOGRID; |
interacts with |
CCT7 | BIOGRID; |
interacts with |
CCT8 | BIOGRID; |
interacts with |
CDCA8 | INTACT; |
interacts with |
CDK2 | BIOGRID; |
interacts with |
CDK6 | BIOGRID; |
interacts with |
CHAF1A | INTACT; |
interacts with |
CHAF1B | INTACT; |
interacts with |
CSNK1A1 | BIOGRID; |
interacts with |
CTNNB1 | CELL_MAP; |
interacts with |
CTTNBP2NL | BIOGRID; |
interacts with |
CTTNBP2 | BIOGRID; |
interacts with |
CXCR2 | HPRD; |
interacts with |
DSN1 | INTACT; |
interacts with |
DVL3 | CELL_MAP; |
interacts with |
DVL3 | HPRD; |
interacts with |
EEF2 | HPRD; |
interacts with |
EHMT1 | INTACT; |
interacts with |
EHMT2 | INTACT; |
interacts with |
EIF4EBP1 | HPRD; |
interacts with |
ETF1 | BIOGRID; |
interacts with |
ETF1 | HPRD; |
interacts with |
FAM40A | BIOGRID; |
interacts with |
FGFR1OP | BIOGRID; |
interacts with |
GABRB3 | HPRD; |
interacts with |
GAD1 | HPRD; |
interacts with |
GOLGA2 | HPRD; |
interacts with |
GSK3B | MINT; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HDAC5 | BIOGRID; |
interacts with |
HDAC7 | BIOGRID; |
interacts with |
IER3 | MINT; |
interacts with |
IGBP1 | BIOGRID; |
interacts with |
IGBP1 | HPRD; |
interacts with |
INCENP | INTACT; |
interacts with |
INTS1 | BIOGRID; |
interacts with |
INTS6 | BIOGRID; |
interacts with |
IPO8 | INTACT; |
interacts with |
IRAK1 | BIOGRID; |
interacts with |
ISYNA1 | BIOGRID; |
interacts with |
ISYNA1 | HPRD; |
interacts with |
ISYNA1 | MINT; |
interacts with |
JAK2 | HPRD; |
interacts with |
KIAA1524 | HPRD; |
interacts with |
KIF23 | HPRD; |
interacts with |
KIF23 | MINT; |
interacts with |
KISS1R | MINT; |
interacts with |
KPNA2 | INTACT; |
interacts with |
KPNA3 | INTACT; |
interacts with |
KPNA4 | INTACT; |
interacts with |
LRIF1 | INTACT; |
interacts with |
MAP7D3 | INTACT; |
interacts with |
MAPK1 | HPRD; |
interacts with |
MAPK3 | HPRD; |
interacts with |
MAPT | HPRD; |
interacts with |
MAU2 | INTACT; |
interacts with |
MID1 | BIOGRID; |
interacts with |
MIS12 | INTACT; |
interacts with |
MOBKL3 | BIOGRID; |
interacts with |
MRPS26 | BIOGRID; |
interacts with |
MRPS26 | HPRD; |
interacts with |
MRPS26 | MINT; |
interacts with |
MST4 | BIOGRID; |
interacts with |
MYC | MINT; |
interacts with |
NARF | INTACT; |
interacts with |
NIPBL | INTACT; |
interacts with |
NME2 | HPRD; |
interacts with |
NSL1 | INTACT; |
interacts with |
NXN | HPRD; |
interacts with |
Nxn | MINT; |
interacts with |
PACS1 | HPRD; |
interacts with |
PDCD10 | BIOGRID; |
interacts with |
PIN1 | MINT; |
interacts with |
PMF1 | INTACT; |
interacts with |
PMS2 | BIOGRID; |
interacts with |
POGZ | INTACT; |
interacts with |
PPFIA1 | BIOGRID; |
interacts with |
PPFIA2 | BIOGRID; |
interacts with |
PPFIA3 | BIOGRID; |
interacts with |
PPM1B | BIOGRID; |
interacts with |
PPME1 | BIOGRID; |
interacts with |
PPP1CA | HPRD; |
interacts with |
PPP2CB | INTACT; |
interacts with |
PPP2R1A | BIOGRID; |
interacts with |
PPP2R1B | BIOGRID; |
interacts with |
PPP2R1B | HPRD; |
interacts with |
PPP2R2A | BIOGRID; |
interacts with |
PPP2R2A | HPRD; |
interacts with |
PPP2R2C | BIOGRID; |
interacts with |
PPP2R2D | BIOGRID; |
interacts with |
PPP2R3A | BIOGRID; |
interacts with |
PPP2R3B | BIOGRID; |
interacts with |
PPP2R5A | BIOGRID; |
interacts with |
PPP2R5A | INTACT; |
interacts with |
PPP2R5A | MINT; |
interacts with |
PPP2R5B | BIOGRID; |
interacts with |
PPP2R5B | HPRD; |
interacts with |
PPP2R5B | MINT; |
interacts with |
PPP2R5C | BIOGRID; |
interacts with |
PPP2R5C | MINT; |
interacts with |
PPP2R5D | BIOGRID; |
interacts with |
PPP2R5E | BIOGRID; |
interacts with |
PPP2R5E | HPRD; |
interacts with |
PPP2R5E | INTACT; |
interacts with |
PPP2R5E | MINT; |
interacts with |
PRKCD | BIOGRID; |
interacts with |
PRKCD | HPRD; |
interacts with |
PRKDC | BIOGRID; |
interacts with |
PRR14 | INTACT; |
interacts with |
PTN | BIOGRID; |
interacts with |
PTN | HPRD; |
interacts with |
PTN | MINT; |
interacts with |
PXN | BIOGRID; |
interacts with |
PXN | HPRD; |
interacts with |
RACGAP1 | HPRD; |
interacts with |
RACGAP1 | MINT; |
interacts with |
RBBP4 | INTACT; |
interacts with |
RBBP7 | INTACT; |
interacts with |
RBL2 | BIOGRID; |
interacts with |
RELA | BIOGRID; |
interacts with |
RELA | HPRD; |
interacts with |
RHO | HPRD; |
interacts with |
RLF | INTACT; |
interacts with |
RPL26L1 | INTACT; |
interacts with |
RPL5 | INTACT; |
interacts with |
RPS6KB1 | HPRD; |
interacts with |
RRAS | HPRD; |
interacts with |
SCAI | INTACT; |
interacts with |
SENP7 | INTACT; |
interacts with |
SET | HPRD; |
interacts with |
SGK1 | BIOGRID; |
interacts with |
SGOL1 | INTACT; |
interacts with |
SIK2 | HPRD; |
interacts with |
SIKE1 | BIOGRID; |
interacts with |
SMARCA2 | INTACT; |
interacts with |
SMARCA4 | INTACT; |
interacts with |
SPRY2 | BIOGRID; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | HPRD; |
interacts with |
STK24 | BIOGRID; |
interacts with |
STK25 | BIOGRID; |
interacts with |
STRN3 | BIOGRID; |
interacts with |
STRN4 | BIOGRID; |
interacts with |
STRN | BIOGRID; |
interacts with |
STRN | HPRD; |
interacts with |
SUV39H1 | INTACT; |
interacts with |
SUV39H2 | INTACT; |
interacts with |
SUZ12 | INTACT; |
interacts with |
TBCD | BIOGRID; |
interacts with |
TCP1 | BIOGRID; |
interacts with |
TERF1 | BIOGRID; |
interacts with |
TIMM50 | INTACT; |
interacts with |
TLX1 | BIOGRID; |
interacts with |
TRAF3IP3 | BIOGRID; |
interacts with |
TRIM28 | INTACT; |
interacts with |
TRIP13 | BIOGRID; |
interacts with |
TRIP13 | HPRD; |
interacts with |
TRIP13 | MINT; |
interacts with |
TSC2 | HPRD; |
interacts with |
VDR | HPRD; |
interacts with |
WIZ | INTACT; |
interacts with |
ZFP1 | INTACT; |
interacts with |
ZFP82 | INTACT; |
interacts with |
ZMYM3 | INTACT; |
interacts with |
ZNF195 | INTACT; |
interacts with |
ZNF227 | INTACT; |
interacts with |
ZNF264 | INTACT; |
interacts with |
ZNF274 | INTACT; |
interacts with |
ZNF280D | INTACT; |
interacts with |
ZNF302 | INTACT; |
interacts with |
ZNF324B | INTACT; |
interacts with |
ZNF324 | INTACT; |
interacts with |
ZNF45 | INTACT; |
interacts with |
ZNF460 | INTACT; |
interacts with |
ZNF462 | INTACT; |
interacts with |
ZNF483 | INTACT; |
interacts with |
ZNF518A | INTACT; |
interacts with |
ZNF552 | INTACT; |
interacts with |
ZNF566 | INTACT; |
interacts with |
ZNF569 | INTACT; |
interacts with |
ZNF585A | INTACT; |
interacts with |
ZNF585B | INTACT; |
interacts with |
ZNF620 | INTACT; |
interacts with |
ZNF625 | INTACT; |
interacts with |
ZNF649 | INTACT; |
interacts with |
ZNF689 | INTACT; |
interacts with |
ZNF724P | INTACT; |
interacts with |
ZNF747 | INTACT; |
interacts with |
ZNF764 | INTACT; |
interacts with |
ZNF773 | INTACT; |
interacts with |
ZNF828 | INTACT; |
interacts with |
ZNF829 | INTACT; |
interacts with |
ZNF8 | INTACT; |
Metabolic Interaction [Top] | ||
There is no record for PPP2CA |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
CASC3 | REACTOME; |
reacts with |
CCNG1 | NCI_NATURE; |
reacts with |
EIF4A3 | REACTOME; |
reacts with |
EIF4G1 | REACTOME; |
reacts with |
ETF1 | REACTOME; |
reacts with |
GSPT2 | REACTOME; |
reacts with |
MAGOH | REACTOME; |
reacts with |
NCBP1 | REACTOME; |
reacts with |
NCBP2 | REACTOME; |
reacts with |
PABPC1 | REACTOME; |
reacts with |
PPP2CA | IMID; |
reacts with |
PPP2CA | NCI_NATURE; |
reacts with |
PPP2CA | REACTOME; |
reacts with |
PPP2R1A | NCI_NATURE; |
reacts with |
PPP2R1A | REACTOME; |
reacts with |
PPP2R2A | NCI_NATURE; |
reacts with |
PPP2R2A | REACTOME; |
reacts with |
PPP2R4 | NCI_NATURE; |
reacts with |
RBM8A | REACTOME; |
reacts with |
RNPS1 | REACTOME; |
reacts with |
RPL10 | REACTOME; |
reacts with |
RPL12 | REACTOME; |
reacts with |
RPL13A | REACTOME; |
reacts with |
RPL13 | REACTOME; |
reacts with |
RPL14 | REACTOME; |
reacts with |
RPL17 | REACTOME; |
reacts with |
RPL18A | REACTOME; |
reacts with |
RPL18 | REACTOME; |
reacts with |
RPL21 | REACTOME; |
reacts with |
RPL22 | REACTOME; |
reacts with |
RPL26L1 | REACTOME; |
reacts with |
RPL27A | REACTOME; |
reacts with |
RPL28 | REACTOME; |
reacts with |
RPL29 | REACTOME; |
reacts with |
RPL34 | REACTOME; |
reacts with |
RPL35A | REACTOME; |
reacts with |
RPL35 | REACTOME; |
reacts with |
RPL36 | REACTOME; |
reacts with |
RPL3L | REACTOME; |
reacts with |
RPL3 | REACTOME; |
reacts with |
RPL4 | REACTOME; |
reacts with |
RPL5 | REACTOME; |
reacts with |
RPL6 | REACTOME; |
reacts with |
RPL7 | REACTOME; |
reacts with |
RPL9 | REACTOME; |
reacts with |
RPLP0 | REACTOME; |
reacts with |
RPLP1 | REACTOME; |
reacts with |
RPLP2 | REACTOME; |
reacts with |
RPS10 | REACTOME; |
reacts with |
RPS12 | REACTOME; |
reacts with |
RPS17 | REACTOME; |
reacts with |
RPS19 | REACTOME; |
reacts with |
RPS21 | REACTOME; |
reacts with |
RPS27 | REACTOME; |
reacts with |
RPS2 | REACTOME; |
reacts with |
RPS3 | REACTOME; |
reacts with |
RPS4Y1 | REACTOME; |
reacts with |
RPS5 | REACTOME; |
reacts with |
RPS9 | REACTOME; |
reacts with |
RPSA | REACTOME; |
reacts with |
SMG1 | REACTOME; |
reacts with |
SMG5 | REACTOME; |
reacts with |
SMG6 | REACTOME; |
reacts with |
SMG7 | REACTOME; |
reacts with |
SMG8 | REACTOME; |
reacts with |
SMG9 | REACTOME; |
reacts with |
SNCA | IMID; |
reacts with |
UPF1 | REACTOME; |
reacts with |
UPF2 | REACTOME; |
state change |
BUB1 | NCI_NATURE; |
state change |
CASC3 | REACTOME; |
state change |
EGF | NCI_NATURE; |
state change |
EGFR | NCI_NATURE; |
state change |
EIF4A3 | REACTOME; |
state change |
EIF4G1 | REACTOME; |
state change |
ETF1 | REACTOME; |
state change |
GSPT2 | REACTOME; |
state change |
MAGOH | REACTOME; |
state change |
NCBP1 | REACTOME; |
state change |
NCBP2 | REACTOME; |
state change |
PABPC1 | REACTOME; |
state change |
PPP2CA | REACTOME; |
state change |
PPP2R1A | REACTOME; |
state change |
PPP2R2A | REACTOME; |
state change |
RBM8A | REACTOME; |
state change |
RNPS1 | REACTOME; |
state change |
RPL10 | REACTOME; |
state change |
RPL12 | REACTOME; |
state change |
RPL13A | REACTOME; |
state change |
RPL13 | REACTOME; |
state change |
RPL14 | REACTOME; |
state change |
RPL17 | REACTOME; |
state change |
RPL18A | REACTOME; |
state change |
RPL18 | REACTOME; |
state change |
RPL21 | REACTOME; |
state change |
RPL22 | REACTOME; |
state change |
RPL26L1 | REACTOME; |
state change |
RPL27A | REACTOME; |
state change |
RPL28 | REACTOME; |
state change |
RPL29 | REACTOME; |
state change |
RPL34 | REACTOME; |
state change |
RPL35A | REACTOME; |
state change |
RPL35 | REACTOME; |
state change |
RPL36 | REACTOME; |
state change |
RPL3L | REACTOME; |
state change |
RPL3 | REACTOME; |
state change |
RPL4 | REACTOME; |
state change |
RPL5 | REACTOME; |
state change |
RPL6 | REACTOME; |
state change |
RPL7 | REACTOME; |
state change |
RPL9 | REACTOME; |
state change |
RPLP0 | REACTOME; |
state change |
RPLP1 | REACTOME; |
state change |
RPLP2 | REACTOME; |
state change |
RPS10 | REACTOME; |
state change |
RPS12 | REACTOME; |
state change |
RPS17 | REACTOME; |
state change |
RPS19 | REACTOME; |
state change |
RPS21 | REACTOME; |
state change |
RPS27 | REACTOME; |
state change |
RPS2 | REACTOME; |
state change |
RPS3 | REACTOME; |
state change |
RPS4Y1 | REACTOME; |
state change |
RPS5 | REACTOME; |
state change |
RPS9 | REACTOME; |
state change |
RPSA | REACTOME; |
state change |
SMG5 | REACTOME; |
state change |
SMG6 | REACTOME; |
state change |
SMG7 | REACTOME; |
state change |
UPF1 | REACTOME; |
state change |
UPF2 | REACTOME; |