Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5770

Name

PTPN1

Synonymous

PTP1B;protein tyrosine phosphatase, non-receptor type 1;PTPN1;protein tyrosine phosphatase, non-receptor type 1

Definition

protein tyrosine phosphatase, placental|protein-tyrosine phosphatase 1B|tyrosine-protein phosphatase non-receptor type 1

Position

20q13.1-q13.2

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AKT1NCI_NATURE;

in same component

 BCAR1NCI_NATURE;

in same component

 CDH2NCI_NATURE;

in same component

 GHRREACTOME;

in same component

 IGF1NCI_NATURE;

in same component

 IGF1RNCI_NATURE;

in same component

 INSNCI_NATURE;

in same component

 INSRNCI_NATURE;

in same component

 IRS1NCI_NATURE;

in same component

 JAK2REACTOME;

in same component

 SHC1NCI_NATURE;

in same component

 TRPV6NCI_NATURE;

interacts with

 ABL1MINT;

interacts with

 ACTA1MINT;

interacts with

 ACTN1HPRD;

interacts with

 AKT1HPRD;

interacts with

 Akt1MINT;

interacts with

 BCAR1BIOGRID;

interacts with

 Bcar1MINT;

interacts with

 BCAR1MINT;

interacts with

 CAPN1MINT;

interacts with

 CAPN2HPRD;

interacts with

 CAPN2MINT;

interacts with

 CAPNS1MINT;

interacts with

 CAV1BIOGRID;

interacts with

 CAV1HPRD;

interacts with

 CAV1MINT;

interacts with

 CDH2HPRD;

interacts with

 CDH2MINT;

interacts with

 CLK1HPRD;

interacts with

 CLK1MINT;

interacts with

 CLK2HPRD;

interacts with

 CLK2MINT;

interacts with

 CRKBIOGRID;

interacts with

 CrkMINT;

interacts with

 CSNK2A1HPRD;

interacts with

 CSNK2A1MINT;

interacts with

 CSNK2A2HPRD;

interacts with

 CTNNB1BIOGRID;

interacts with

 CTNNB1HPRD;

interacts with

 Ctnnd1MINT;

interacts with

 CttnMINT;

interacts with

 CTTNMINT;

interacts with

 Dlg4MINT;

interacts with

 Dok1MINT;

interacts with

 EGFRBIOGRID;

interacts with

 EGFRHPRD;

interacts with

 EgfrMINT;

interacts with

 EGFRMINT;

interacts with

 EPORMINT;

interacts with

 ESR1HPRD;

interacts with

 ESR1MINT;

interacts with

 GHRBIOGRID;

interacts with

 GHRMINT;

interacts with

 GLRXHPRD;

interacts with

 Grb2MINT;

interacts with

 GSK3BBIOGRID;

interacts with

 GSK3BHPRD;

interacts with

 GSK3BMINT;

interacts with

 IGF1RBIOGRID;

interacts with

 IGF1RHPRD;

interacts with

 IGF1RMINT;

interacts with

 Inppl1MINT;

interacts with

 INSRBIOGRID;

interacts with

 INSRHPRD;

interacts with

 InsrMINT;

interacts with

 INSRMINT;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1HPRD;

interacts with

 Irs1MINT;

interacts with

 IRS1MINT;

interacts with

 ITGB3MINT;

interacts with

 JAK2BIOGRID;

interacts with

 JAK2HPRD;

interacts with

 Jak2MINT;

interacts with

 JAK2MINT;

interacts with

 LATHPRD;

interacts with

 LATMINT;

interacts with

 LppMINT;

interacts with

 LTKBIOGRID;

interacts with

 LTKMINT;

interacts with

 MAPK1HPRD;

interacts with

 METMINT;

interacts with

 NFKBIAHPRD;

interacts with

 NFKBIAMINT;

interacts with

 NTRK2BIOGRID;

interacts with

 NTRK3BIOGRID;

interacts with

 NTRK3MINT;

interacts with

 PDGFRBHPRD;

interacts with

 PdgfrbMINT;

interacts with

 PDGFRBMINT;

interacts with

 PIAS1HPRD;

interacts with

 PIAS1MINT;

interacts with

 PIN1HPRD;

interacts with

 Plcg1MINT;

interacts with

 PLD2MINT;

interacts with

 PRKCGMINT;

interacts with

 PSTPIP1MINT;

interacts with

 Ptk2MINT;

interacts with

 PTK2MINT;

interacts with

 PXNHPRD;

interacts with

 PxnMINT;

interacts with

 ROS1MINT;

interacts with

 SLC4A1MINT;

interacts with

 SRCHPRD;

interacts with

 SrcMINT;

interacts with

 SRCMINT;

interacts with

 STAT3MINT;

interacts with

 STAT5ABIOGRID;

interacts with

 STAT5AHPRD;

interacts with

 STAT5AMINT;

interacts with

 STAT5BBIOGRID;

interacts with

 STAT5BHPRD;

interacts with

 STAT5BMINT;

interacts with

 Tjp1MINT;

interacts with

 TRPV6HPRD;

interacts with

 Trpv6MINT;

interacts with

 TRPV6MINT;

interacts with

 TYK2BIOGRID;

interacts with

 TYK2HPRD;

interacts with

 TYK2MINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 INSNCI_NATURE;

metabolic catalysis

 INSRNCI_NATURE;

metabolic catalysis

 NFATC2NCI_NATURE;

metabolic catalysis

 YBX1NCI_NATURE;

sequential catalysis

 PTPN1HUMANCYC;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AKT1NCI_NATURE;

reacts with

 BCAR1NCI_NATURE;

reacts with

 CDH2NCI_NATURE;

reacts with

 GHRREACTOME;

reacts with

 IGF1NCI_NATURE;

reacts with

 IGF1RNCI_NATURE;

reacts with

 INSNCI_NATURE;

reacts with

 INSRNCI_NATURE;

reacts with

 IRS1NCI_NATURE;

reacts with

 JAK2REACTOME;

reacts with

 PTPN1NCI_NATURE;

reacts with

 PTPN1REACTOME;

reacts with

 SHC1NCI_NATURE;

reacts with

 TRPV6NCI_NATURE;

state change

 EGFNCI_NATURE;

state change

 EGFRNCI_NATURE;

state change

 FERNCI_NATURE;

state change

 GHRREACTOME;

state change

 INSNCI_NATURE;

state change

 INSRNCI_NATURE;

state change

 JAK2REACTOME;

state change

 NOX4NCI_NATURE;

state change

 PTPN1REACTOME;

state change

 RHOANCI_NATURE;

state change

 SPRY2NCI_NATURE;

state change

 TXNNCI_NATURE;

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