General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 5781 |
Name | PTPN11 |
Synonymous | BPTP3|CFC|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2;protein tyrosine phosphatase, non-receptor type 11;PTPN11;protein tyrosine phosphatase, non-receptor type 11 |
Definition | PTP-2C|protein-tyrosine phosphatase 1D|protein-tyrosine phosphatase 2C|tyrosine-protein phosphatase non-receptor type 11 |
Position | 12q24 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ANGPT1 | REACTOME; |
in same component |
CBL | REACTOME; |
in same component |
CSF2 | NCI_NATURE; |
in same component |
CSF2RA | NCI_NATURE; |
in same component |
CSF2RB | NCI_NATURE; |
in same component |
CTLA4 | REACTOME; |
in same component |
DCC | REACTOME; |
in same component |
EGF | REACTOME; |
in same component |
EGFR | REACTOME; |
in same component |
FLT1 | NCI_NATURE; |
in same component |
FRS2 | NCI_NATURE; |
in same component |
FRS2 | REACTOME; |
in same component |
GAB1 | NCI_NATURE; |
in same component |
GAB1 | REACTOME; |
in same component |
GAB2 | NCI_NATURE; |
in same component |
GAB2 | REACTOME; |
in same component |
GDNF | NCI_NATURE; |
in same component |
GFRA1 | NCI_NATURE; |
in same component |
HGF | NCI_NATURE; |
in same component |
IGF1 | NCI_NATURE; |
in same component |
IGF1R | NCI_NATURE; |
in same component |
IL2 | NCI_NATURE; |
in same component |
IL2RA | NCI_NATURE; |
in same component |
IL2RB | NCI_NATURE; |
in same component |
IL2RG | NCI_NATURE; |
in same component |
IL3 | NCI_NATURE; |
in same component |
IL3RA | NCI_NATURE; |
in same component |
IL5 | NCI_NATURE; |
in same component |
IL5RA | NCI_NATURE; |
in same component |
INPP5D | NCI_NATURE; |
in same component |
INS | NCI_NATURE; |
in same component |
INSR | NCI_NATURE; |
in same component |
IRS1 | NCI_NATURE; |
in same component |
JAK1 | NCI_NATURE; |
in same component |
JAK2 | NCI_NATURE; |
in same component |
JAK3 | NCI_NATURE; |
in same component |
KIT | REACTOME; |
in same component |
KLRG1 | NCI_NATURE; |
in same component |
LCK | NCI_NATURE; |
in same component |
MET | NCI_NATURE; |
in same component |
MLLT4 | NCI_NATURE; |
in same component |
NOS3 | NCI_NATURE; |
in same component |
NTN1 | REACTOME; |
in same component |
PDGFB | NCI_NATURE; |
in same component |
PDGFRB | IMID; |
in same component |
PDGFRB | NCI_NATURE; |
in same component |
PECAM1 | REACTOME; |
in same component |
PIK3CA | IMID; |
in same component |
PIK3CA | NCI_NATURE; |
in same component |
PIK3CA | REACTOME; |
in same component |
PIK3R1 | NCI_NATURE; |
in same component |
PIK3R1 | REACTOME; |
in same component |
PRKACA | NCI_NATURE; |
in same component |
PTK2B | NCI_NATURE; |
in same component |
PTK2 | REACTOME; |
in same component |
RAPGEF1 | NCI_NATURE; |
in same component |
SDC2 | NCI_NATURE; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SOS1 | NCI_NATURE; |
in same component |
STAT1 | NCI_NATURE; |
in same component |
TEK | NCI_NATURE; |
in same component |
TEK | REACTOME; |
in same component |
UNC5C | REACTOME; |
in same component |
VEGFA | NCI_NATURE; |
interacts with |
ACTB | INTACT; |
interacts with |
ACTN4 | HPRD; |
interacts with |
Agtr1 | MINT; |
interacts with |
ALB | INTACT; |
interacts with |
ALDOA | INTACT; |
interacts with |
ANGPT2 | INTACT; |
interacts with |
ANKAR | INTACT; |
interacts with |
ANXA2 | INTACT; |
interacts with |
ARHGAP1 | HPRD; |
interacts with |
ARHGAP20 | INTACT; |
interacts with |
ASAP1 | INTACT; |
interacts with |
ASAP2 | INTACT; |
interacts with |
ASPH | INTACT; |
interacts with |
ATP1A1 | INTACT; |
interacts with |
ATP5A1 | INTACT; |
interacts with |
ATP6V1G2 | INTACT; |
interacts with |
AXL | HPRD; |
interacts with |
BCAR1 | BIOGRID; |
interacts with |
BDKRB2 | HPRD; |
interacts with |
BOLA2 | INTACT; |
interacts with |
BPNT1 | INTACT; |
interacts with |
BTLA | BIOGRID; |
interacts with |
BTLA | HPRD; |
interacts with |
BTLA | MINT; |
interacts with |
C11orf84 | INTACT; |
interacts with |
CAB39 | INTACT; |
interacts with |
CALB1 | INTACT; |
interacts with |
CALCOCO2 | INTACT; |
interacts with |
CALM1 | INTACT; |
interacts with |
CALU | INTACT; |
interacts with |
CAT | HPRD; |
interacts with |
CAT | MINT; |
interacts with |
CAV1 | BIOGRID; |
interacts with |
CAV1 | HPRD; |
interacts with |
CAV1 | MINT; |
interacts with |
CBLB | INTACT; |
interacts with |
CBL | BIOGRID; |
interacts with |
CBL | HPRD; |
interacts with |
CBL | INTACT; |
interacts with |
CCKBR | HPRD; |
interacts with |
CCKBR | MINT; |
interacts with |
Cd244 | BIOGRID; |
interacts with |
CD2AP | INTACT; |
interacts with |
CD33 | BIOGRID; |
interacts with |
CD33 | HPRD; |
interacts with |
CD33 | MINT; |
interacts with |
CD84 | BIOGRID; |
interacts with |
CDH5 | BIOGRID; |
interacts with |
CDH5 | HPRD; |
interacts with |
CDIPT | INTACT; |
interacts with |
CEACAM1 | BIOGRID; |
interacts with |
CEACAM1 | HPRD; |
interacts with |
CEP290 | INTACT; |
interacts with |
CHUK | CELL_MAP; |
interacts with |
CHUK | HPRD; |
interacts with |
CKB | INTACT; |
interacts with |
CKM | INTACT; |
interacts with |
CKMT1A | INTACT; |
interacts with |
CNTNAP2 | INTACT; |
interacts with |
CPLX1 | INTACT; |
interacts with |
CRISPLD2 | INTACT; |
interacts with |
CRKL | BIOGRID; |
interacts with |
CRKL | HPRD; |
interacts with |
CRK | HPRD; |
interacts with |
CSF2RB | BIOGRID; |
interacts with |
CSF2RB | HPRD; |
interacts with |
CSF2RB | MINT; |
interacts with |
CSF3R | BIOGRID; |
interacts with |
CSF3R | HPRD; |
interacts with |
CSK | INTACT; |
interacts with |
CSK | MINT; |
interacts with |
CSRP1 | INTACT; |
interacts with |
CTLA4 | HPRD; |
interacts with |
CTNNB1 | BIOGRID; |
interacts with |
CXCR4 | HPRD; |
interacts with |
DAB1 | HPRD; |
interacts with |
DCD | INTACT; |
interacts with |
DDAH1 | INTACT; |
interacts with |
DDR1 | HPRD; |
interacts with |
DDR1 | MINT; |
interacts with |
DIAPH1 | INTACT; |
interacts with |
DNAJA1 | INTACT; |
interacts with |
DNM1 | INTACT; |
interacts with |
DOCK4 | INTACT; |
interacts with |
DOCK5 | INTACT; |
interacts with |
DOK1 | MINT; |
interacts with |
DPYSL2 | INTACT; |
interacts with |
DSG1 | INTACT; |
interacts with |
DSP | INTACT; |
interacts with |
DTD1 | INTACT; |
interacts with |
DYNLL1 | INTACT; |
interacts with |
ECH1 | INTACT; |
interacts with |
EEF1A1 | INTACT; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | CELL_MAP; |
interacts with |
EGFR | HPRD; |
interacts with |
EGFR | INTACT; |
interacts with |
EGFR | MINT; |
interacts with |
EIF5A | INTACT; |
interacts with |
ELMO2 | INTACT; |
interacts with |
EMD | INTACT; |
interacts with |
ENO3 | INTACT; |
interacts with |
EPHA2 | BIOGRID; |
interacts with |
EPHA2 | HPRD; |
interacts with |
EPHA2 | INTACT; |
interacts with |
EPOR | BIOGRID; |
interacts with |
EPOR | HPRD; |
interacts with |
Epor | MINT; |
interacts with |
EPS15L1 | INTACT; |
interacts with |
ERBB2 | BIOGRID; |
interacts with |
ERBB2 | HPRD; |
interacts with |
ERBB2 | MINT; |
interacts with |
ERBB4 | BIOGRID; |
interacts with |
ERBB4 | MINT; |
interacts with |
ERC2 | INTACT; |
interacts with |
ERRFI1 | INTACT; |
interacts with |
EXOC1 | INTACT; |
interacts with |
EXOC4 | INTACT; |
interacts with |
FAM59A | INTACT; |
interacts with |
FAM59B | INTACT; |
interacts with |
FAR1 | INTACT; |
interacts with |
FBXO2 | INTACT; |
interacts with |
FCGR2B | BIOGRID; |
interacts with |
FCGR2B | MINT; |
interacts with |
FCRL3 | BIOGRID; |
interacts with |
FGD6 | INTACT; |
interacts with |
FH | INTACT; |
interacts with |
FLG2 | INTACT; |
interacts with |
FLNA | INTACT; |
interacts with |
FLNC | INTACT; |
interacts with |
FLT3 | MINT; |
interacts with |
FLT4 | HPRD; |
interacts with |
FRS2 | BIOGRID; |
interacts with |
FRS2 | HPRD; |
interacts with |
FRS2 | INTACT; |
interacts with |
FRS2 | MINT; |
interacts with |
FRS3 | HPRD; |
interacts with |
FRS3 | MINT; |
interacts with |
FSCN1 | INTACT; |
interacts with |
FYCO1 | INTACT; |
interacts with |
FYN | BIOGRID; |
interacts with |
FYN | HPRD; |
interacts with |
G6B | BIOGRID; |
interacts with |
G6B | MINT; |
interacts with |
GAB1 | BIOGRID; |
interacts with |
GAB1 | CELL_MAP; |
interacts with |
GAB1 | HPRD; |
interacts with |
GAB1 | MINT; |
interacts with |
GAB2 | BIOGRID; |
interacts with |
Gab2 | CELL_MAP; |
interacts with |
GAB2 | HPRD; |
interacts with |
GAB2 | INTACT; |
interacts with |
Gab2 | MINT; |
interacts with |
GAB2 | MINT; |
interacts with |
GAB3 | BIOGRID; |
interacts with |
GAB3 | HPRD; |
interacts with |
GAPDH | INTACT; |
interacts with |
GAS8 | INTACT; |
interacts with |
GDI1 | INTACT; |
interacts with |
GDI2 | INTACT; |
interacts with |
GEMIN4 | INTACT; |
interacts with |
GHR | BIOGRID; |
interacts with |
GHR | HPRD; |
interacts with |
Ghr | MINT; |
interacts with |
GIT1 | INTACT; |
interacts with |
GNAI1 | INTACT; |
interacts with |
GPC4 | INTACT; |
interacts with |
GRB10 | INTACT; |
interacts with |
GRIN2B | HPRD; |
interacts with |
GSTM1 | INTACT; |
interacts with |
GUK1 | INTACT; |
interacts with |
HADHA | INTACT; |
interacts with |
HADHB | INTACT; |
interacts with |
HBA1 | INTACT; |
interacts with |
HDGFRP3 | INTACT; |
interacts with |
HGS | INTACT; |
interacts with |
HIRIP3 | INTACT; |
interacts with |
HNRNPA2B1 | INTACT; |
interacts with |
HNRNPF | INTACT; |
interacts with |
HNRNPU | HPRD; |
interacts with |
HRNR | INTACT; |
interacts with |
HSP90AA1 | INTACT; |
interacts with |
HSPA5 | INTACT; |
interacts with |
HSPA6 | INTACT; |
interacts with |
HSPA8 | INTACT; |
interacts with |
HSPA9 | INTACT; |
interacts with |
HSPB1 | INTACT; |
interacts with |
HUNK | INTACT; |
interacts with |
IFNAR1 | HPRD; |
interacts with |
IFNGR1 | HPRD; |
interacts with |
IGF1R | BIOGRID; |
interacts with |
IGF1R | HPRD; |
interacts with |
IGF1R | MINT; |
interacts with |
IGF2BP1 | INTACT; |
interacts with |
IGHG1 | INTACT; |
interacts with |
IL4R | BIOGRID; |
interacts with |
IL4R | HPRD; |
interacts with |
IL6ST | BIOGRID; |
interacts with |
IL6ST | HPRD; |
interacts with |
INPP5D | BIOGRID; |
interacts with |
INPP5D | HPRD; |
interacts with |
INPPL1 | INTACT; |
interacts with |
INSR | BIOGRID; |
interacts with |
INSR | HPRD; |
interacts with |
INSR | MINT; |
interacts with |
IQCB1 | INTACT; |
interacts with |
IQGAP3 | INTACT; |
interacts with |
IRS1 | BIOGRID; |
interacts with |
IRS1 | HPRD; |
interacts with |
IRS1 | INTACT; |
interacts with |
Irs1 | MINT; |
interacts with |
IRS1 | MINT; |
interacts with |
IRS2 | BIOGRID; |
interacts with |
IRS2 | HPRD; |
interacts with |
IRS2 | INTACT; |
interacts with |
IRS4 | HPRD; |
interacts with |
IRS4 | INTACT; |
interacts with |
ITGA11 | INTACT; |
interacts with |
ITGB3 | MINT; |
interacts with |
JAK1 | BIOGRID; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | BIOGRID; |
interacts with |
JAK2 | HPRD; |
interacts with |
KDR | HPRD; |
interacts with |
KHDRBS1 | INTACT; |
interacts with |
KIR2DL1 | MINT; |
interacts with |
KIR2DL3 | MINT; |
interacts with |
KIR2DL5A | HPRD; |
interacts with |
KIT | BIOGRID; |
interacts with |
Kit | CELL_MAP; |
interacts with |
KIT | HPRD; |
interacts with |
Kit | MINT; |
interacts with |
KLRC1 | HPRD; |
interacts with |
LAIR1 | BIOGRID; |
interacts with |
LAIR1 | HPRD; |
interacts with |
LCK | HPRD; |
interacts with |
LDHAL6A | INTACT; |
interacts with |
LEPR | HPRD; |
interacts with |
LEPR | MINT; |
interacts with |
LIFR | HPRD; |
interacts with |
LILRB4 | BIOGRID; |
interacts with |
LILRB4 | HPRD; |
interacts with |
LOX | INTACT; |
interacts with |
LPCAT2 | INTACT; |
interacts with |
LTN1 | INTACT; |
interacts with |
LY9 | BIOGRID; |
interacts with |
MAG | INTACT; |
interacts with |
MAP1B | INTACT; |
interacts with |
MAP3K4 | HPRD; |
interacts with |
MAP4K5 | INTACT; |
interacts with |
MAPK3 | HPRD; |
interacts with |
MAPRE1 | INTACT; |
interacts with |
MDH1 | INTACT; |
interacts with |
MET | HPRD; |
interacts with |
MET | MINT; |
interacts with |
MPL | HPRD; |
interacts with |
MPZL1 | BIOGRID; |
interacts with |
MPZL1 | HPRD; |
interacts with |
MPZL1 | MINT; |
interacts with |
MRPL16 | INTACT; |
interacts with |
MS4A2 | HPRD; |
interacts with |
MSR1 | INTACT; |
interacts with |
MVP | HPRD; |
interacts with |
MYCBP | INTACT; |
interacts with |
MYH9 | INTACT; |
interacts with |
MYO1C | INTACT; |
interacts with |
NAP1L1 | INTACT; |
interacts with |
NCKAP1 | INTACT; |
interacts with |
NEDD9 | HPRD; |
interacts with |
NEFM | INTACT; |
interacts with |
NGF | HPRD; |
interacts with |
NISCH | INTACT; |
interacts with |
NUDT3 | INTACT; |
interacts with |
NUP188 | INTACT; |
interacts with |
ODR4 | INTACT; |
interacts with |
OXCT1 | INTACT; |
interacts with |
PAFAH1B1 | INTACT; |
interacts with |
PAG1 | HPRD; |
interacts with |
PCP4L1 | INTACT; |
interacts with |
PCP4 | INTACT; |
interacts with |
PDCD1 | MINT; |
interacts with |
PDGFRA | HPRD; |
interacts with |
PDGFRB | BIOGRID; |
interacts with |
PDGFRB | HPRD; |
interacts with |
Pdgfrb | MINT; |
interacts with |
PDGFRB | MINT; |
interacts with |
PEA15 | INTACT; |
interacts with |
PEAK1 | INTACT; |
interacts with |
PEBP1 | INTACT; |
interacts with |
PECAM1 | BIOGRID; |
interacts with |
PECAM1 | HPRD; |
interacts with |
PECAM1 | MINT; |
interacts with |
PFDN2 | INTACT; |
interacts with |
PGAM1 | INTACT; |
interacts with |
PGD | INTACT; |
interacts with |
PGK1 | INTACT; |
interacts with |
PIK3AP1 | INTACT; |
interacts with |
PIK3C2B | INTACT; |
interacts with |
PIK3CA | INTACT; |
interacts with |
PIK3CB | INTACT; |
interacts with |
PIK3R1 | BIOGRID; |
interacts with |
PIK3R1 | HPRD; |
interacts with |
PIK3R1 | INTACT; |
interacts with |
PIK3R2 | INTACT; |
interacts with |
PIK3R3 | INTACT; |
interacts with |
PILRA | BIOGRID; |
interacts with |
PILRA | HPRD; |
interacts with |
PILRB | HPRD; |
interacts with |
PLCG2 | BIOGRID; |
interacts with |
PPM1B | INTACT; |
interacts with |
PPP1CA | INTACT; |
interacts with |
PPP3R1 | INTACT; |
interacts with |
PPP5C | INTACT; |
interacts with |
PRDX1 | INTACT; |
interacts with |
PRKCA | HPRD; |
interacts with |
PRKCB | HPRD; |
interacts with |
PRKCH | HPRD; |
interacts with |
PRKDC | INTACT; |
interacts with |
PRLR | BIOGRID; |
interacts with |
PRLR | HPRD; |
interacts with |
PSMA1 | INTACT; |
interacts with |
PSMA2 | INTACT; |
interacts with |
PSMA3 | INTACT; |
interacts with |
PSMA4 | INTACT; |
interacts with |
PSMA5 | INTACT; |
interacts with |
PSMA6 | INTACT; |
interacts with |
PSMA7 | INTACT; |
interacts with |
PSMB1 | INTACT; |
interacts with |
PSMB2 | INTACT; |
interacts with |
PSMB3 | INTACT; |
interacts with |
PSMB5 | INTACT; |
interacts with |
PSMB6 | INTACT; |
interacts with |
PSMB7 | INTACT; |
interacts with |
PSTPIP2 | INTACT; |
interacts with |
PTK2B | BIOGRID; |
interacts with |
PTK2B | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTPLAD1 | INTACT; |
interacts with |
PTPN12 | INTACT; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PXN | HPRD; |
interacts with |
PXN | MINT; |
interacts with |
QDPR | INTACT; |
interacts with |
RAB14 | INTACT; |
interacts with |
RAB1A | INTACT; |
interacts with |
RAB35 | INTACT; |
interacts with |
RAB3C | INTACT; |
interacts with |
RADIL | INTACT; |
interacts with |
RAPGEF1 | HPRD; |
interacts with |
RCN2 | INTACT; |
interacts with |
RNH1 | INTACT; |
interacts with |
ROS1 | BIOGRID; |
interacts with |
RRBP1 | INTACT; |
interacts with |
SEC16A | INTACT; |
interacts with |
SELE | BIOGRID; |
interacts with |
SELE | HPRD; |
interacts with |
SELE | MINT; |
interacts with |
SERPINH1 | INTACT; |
interacts with |
SGPL1 | INTACT; |
interacts with |
SH2D5 | INTACT; |
interacts with |
SH3BGRL2 | INTACT; |
interacts with |
SH3PXD2A | INTACT; |
interacts with |
SH3PXD2B | INTACT; |
interacts with |
SHC1 | HPRD; |
interacts with |
SHC1 | INTACT; |
interacts with |
SIGLEC11 | BIOGRID; |
interacts with |
SIGLEC11 | HPRD; |
interacts with |
SIGLEC12 | HPRD; |
interacts with |
SIGLEC7 | HPRD; |
interacts with |
SIP1 | INTACT; |
interacts with |
SIRPA | HPRD; |
interacts with |
SIRPA | INTACT; |
interacts with |
Sirpa | MINT; |
interacts with |
SIT1 | BIOGRID; |
interacts with |
SIT1 | HPRD; |
interacts with |
SIT1 | MINT; |
interacts with |
SKP1 | INTACT; |
interacts with |
SLAIN2 | INTACT; |
interacts with |
SLAMF1 | BIOGRID; |
interacts with |
SLAMF1 | HPRD; |
interacts with |
SLAMF1 | MINT; |
interacts with |
SLAMF6 | BIOGRID; |
interacts with |
SLC25A13 | INTACT; |
interacts with |
SLC25A3 | INTACT; |
interacts with |
SLC25A5 | INTACT; |
interacts with |
SLC25A6 | INTACT; |
interacts with |
SLC4A1 | MINT; |
interacts with |
SLC5A3 | INTACT; |
interacts with |
SMN1 | INTACT; |
interacts with |
SOCS3 | BIOGRID; |
interacts with |
SOCS3 | HPRD; |
interacts with |
SOS1 | BIOGRID; |
interacts with |
SOS1 | HPRD; |
interacts with |
SOS1 | INTACT; |
interacts with |
SOS2 | INTACT; |
interacts with |
SPATA24 | INTACT; |
interacts with |
SPRY2 | HPRD; |
interacts with |
SQRDL | INTACT; |
interacts with |
SRC | HPRD; |
interacts with |
SRC | MINT; |
interacts with |
STAMBP | INTACT; |
interacts with |
STAT1 | HPRD; |
interacts with |
STAT3 | BIOGRID; |
interacts with |
STAT3 | HPRD; |
interacts with |
STAT5A | BIOGRID; |
interacts with |
STAT5A | HPRD; |
interacts with |
STAT5B | BIOGRID; |
interacts with |
STAT5B | HPRD; |
interacts with |
SVOPL | INTACT; |
interacts with |
SYN2 | INTACT; |
interacts with |
SYNCRIP | BIOGRID; |
interacts with |
SYNJ1 | INTACT; |
interacts with |
TEC | INTACT; |
interacts with |
THBS1 | INTACT; |
interacts with |
TIE1 | HPRD; |
interacts with |
TNFRSF1A | HPRD; |
interacts with |
TNFRSF1A | MINT; |
interacts with |
TPI1 | INTACT; |
interacts with |
TREML1 | BIOGRID; |
interacts with |
TREML1 | HPRD; |
interacts with |
TRIM21 | INTACT; |
interacts with |
TSG101 | INTACT; |
interacts with |
TTYH2 | INTACT; |
interacts with |
TUBA1A | INTACT; |
interacts with |
TUBA1C | INTACT; |
interacts with |
TUBA4A | INTACT; |
interacts with |
TUBA4B | INTACT; |
interacts with |
TUBB2A | INTACT; |
interacts with |
TUBB2C | INTACT; |
interacts with |
TUBB3 | INTACT; |
interacts with |
TUBB6 | INTACT; |
interacts with |
TUBB8 | INTACT; |
interacts with |
TUBB | INTACT; |
interacts with |
TWF2 | INTACT; |
interacts with |
UBE2K | INTACT; |
interacts with |
UBE2V1 | INTACT; |
interacts with |
UBE3B | INTACT; |
interacts with |
UCHL1 | INTACT; |
interacts with |
VAMP2 | INTACT; |
interacts with |
VAV3 | INTACT; |
interacts with |
WASL | INTACT; |
interacts with |
WDR44 | INTACT; |
interacts with |
WDR6 | INTACT; |
interacts with |
WDR77 | INTACT; |
interacts with |
WIPF1 | INTACT; |
interacts with |
WIPF2 | INTACT; |
interacts with |
WIPF3 | INTACT; |
interacts with |
XPOT | INTACT; |
interacts with |
YBX1 | INTACT; |
interacts with |
YWHAB | INTACT; |
interacts with |
YWHAE | INTACT; |
interacts with |
YWHAG | INTACT; |
interacts with |
YWHAH | INTACT; |
interacts with |
YWHAQ | INTACT; |
interacts with |
YWHAZ | INTACT; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
sequential catalysis |
PTPN11 | HUMANCYC; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ANGPT1 | REACTOME; |
reacts with |
CBL | REACTOME; |
reacts with |
CSF2 | NCI_NATURE; |
reacts with |
CSF2RA | NCI_NATURE; |
reacts with |
CSF2RB | NCI_NATURE; |
reacts with |
CTLA4 | REACTOME; |
reacts with |
DCC | REACTOME; |
reacts with |
EGF | REACTOME; |
reacts with |
EGFR | REACTOME; |
reacts with |
FLT1 | NCI_NATURE; |
reacts with |
FRS2 | NCI_NATURE; |
reacts with |
FRS2 | REACTOME; |
reacts with |
GAB1 | NCI_NATURE; |
reacts with |
GAB1 | REACTOME; |
reacts with |
GAB2 | NCI_NATURE; |
reacts with |
GAB2 | REACTOME; |
reacts with |
GDNF | NCI_NATURE; |
reacts with |
GFRA1 | NCI_NATURE; |
reacts with |
HGF | NCI_NATURE; |
reacts with |
IGF1 | NCI_NATURE; |
reacts with |
IGF1R | NCI_NATURE; |
reacts with |
IL2 | NCI_NATURE; |
reacts with |
IL2RA | NCI_NATURE; |
reacts with |
IL2RB | NCI_NATURE; |
reacts with |
IL2RG | NCI_NATURE; |
reacts with |
IL3 | NCI_NATURE; |
reacts with |
IL3RA | NCI_NATURE; |
reacts with |
IL5 | NCI_NATURE; |
reacts with |
IL5RA | NCI_NATURE; |
reacts with |
INPP5D | NCI_NATURE; |
reacts with |
INS | NCI_NATURE; |
reacts with |
INSR | NCI_NATURE; |
reacts with |
IRS1 | NCI_NATURE; |
reacts with |
JAK1 | NCI_NATURE; |
reacts with |
JAK2 | NCI_NATURE; |
reacts with |
JAK3 | NCI_NATURE; |
reacts with |
KIT | REACTOME; |
reacts with |
KLRG1 | NCI_NATURE; |
reacts with |
LCK | NCI_NATURE; |
reacts with |
MET | NCI_NATURE; |
reacts with |
MLLT4 | NCI_NATURE; |
reacts with |
NOS3 | NCI_NATURE; |
reacts with |
NTN1 | REACTOME; |
reacts with |
PDGFB | NCI_NATURE; |
reacts with |
PDGFRB | IMID; |
reacts with |
PDGFRB | NCI_NATURE; |
reacts with |
PECAM1 | REACTOME; |
reacts with |
PIK3CA | IMID; |
reacts with |
PIK3CA | NCI_NATURE; |
reacts with |
PIK3CA | REACTOME; |
reacts with |
PIK3R1 | NCI_NATURE; |
reacts with |
PIK3R1 | REACTOME; |
reacts with |
PRKACA | NCI_NATURE; |
reacts with |
PTK2B | NCI_NATURE; |
reacts with |
PTK2 | REACTOME; |
reacts with |
PTPN11 | IMID; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
PTPN11 | REACTOME; |
reacts with |
RAPGEF1 | NCI_NATURE; |
reacts with |
SDC2 | NCI_NATURE; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SOS1 | NCI_NATURE; |
reacts with |
STAT1 | NCI_NATURE; |
reacts with |
TEK | NCI_NATURE; |
reacts with |
TEK | REACTOME; |
reacts with |
UNC5C | REACTOME; |
reacts with |
VEGFA | NCI_NATURE; |
state change |
CBL | REACTOME; |
state change |
CD247 | NCI_NATURE; |
state change |
CD3D | NCI_NATURE; |
state change |
CD3E | NCI_NATURE; |
state change |
CD3G | NCI_NATURE; |
state change |
CD4 | NCI_NATURE; |
state change |
CDH2 | NCI_NATURE; |
state change |
CTNNA1 | NCI_NATURE; |
state change |
CTNNB1 | NCI_NATURE; |
state change |
CTNND1 | NCI_NATURE; |
state change |
EGF | NCI_NATURE; |
state change |
EGFR | NCI_NATURE; |
state change |
ERBB2 | NCI_NATURE; |
state change |
ERBB3 | NCI_NATURE; |
state change |
FCER1A | NCI_NATURE; |
state change |
FCER1G | NCI_NATURE; |
state change |
FER | NCI_NATURE; |
state change |
FRS2 | REACTOME; |
state change |
FYN | NCI_NATURE; |
state change |
GAB1 | NCI_NATURE; |
state change |
GAB2 | REACTOME; |
state change |
GNAI1 | NCI_NATURE; |
state change |
GNAI3 | NCI_NATURE; |
state change |
HCK | NCI_NATURE; |
state change |
HLA-DRA | NCI_NATURE; |
state change |
HLA-DRB1 | NCI_NATURE; |
state change |
IFNG | NCI_NATURE; |
state change |
IFNGR1 | NCI_NATURE; |
state change |
IGF1 | NCI_NATURE; |
state change |
IGF1R | NCI_NATURE; |
state change |
IGHE | NCI_NATURE; |
state change |
IL6 | NCI_NATURE; |
state change |
IL6R | NCI_NATURE; |
state change |
IL6ST | NCI_NATURE; |
state change |
IRS1 | NCI_NATURE; |
state change |
JAK1 | NCI_NATURE; |
state change |
JAK2 | NCI_NATURE; |
state change |
KDR | NCI_NATURE; |
state change |
KIT | REACTOME; |
state change |
Mapk3 | CELL_MAP; |
state change |
MS4A2 | NCI_NATURE; |
state change |
PTPN11 | REACTOME; |
state change |
RHOA | NCI_NATURE; |
state change |
SOCS3 | NCI_NATURE; |