General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 5788 |
Name | PTPRC |
Synonymous | B220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200;protein tyrosine phosphatase, receptor type, C;PTPRC;protein tyrosine phosphatase, receptor type, C |
Definition | CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase, receptor type, c polypeptide|receptor-type tyrosine-protein phosphatase C |
Position | 1q31-q32 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
CXCL12 | NCI_NATURE; |
in same component |
CXCR4 | NCI_NATURE; |
in same component |
SEMA4D | REACTOME; |
interacts with |
ANP32A | HPRD; |
interacts with |
CD1D | BIOGRID; |
interacts with |
CD1D | HPRD; |
interacts with |
CD22 | BIOGRID; |
interacts with |
CD247 | BIOGRID; |
interacts with |
CD247 | HPRD; |
interacts with |
CD28 | HPRD; |
interacts with |
CD2 | BIOGRID; |
interacts with |
CD2 | HPRD; |
interacts with |
CD44 | BIOGRID; |
interacts with |
CD4 | BIOGRID; |
interacts with |
CD4 | HPRD; |
interacts with |
CD79A | BIOGRID; |
interacts with |
CD79A | HPRD; |
interacts with |
CD79B | BIOGRID; |
interacts with |
CD79B | HPRD; |
interacts with |
CD8A | BIOGRID; |
interacts with |
CD8A | HPRD; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CSNK2A2 | HPRD; |
interacts with |
CXCR4 | HPRD; |
interacts with |
DPP4 | HPRD; |
interacts with |
EZR | HPRD; |
interacts with |
FCGR3A | HPRD; |
interacts with |
FYN | HPRD; |
interacts with |
GANAB | BIOGRID; |
interacts with |
GANAB | HPRD; |
interacts with |
IFNAR1 | HPRD; |
interacts with |
INSR | HPRD; |
interacts with |
IRS1 | HPRD; |
interacts with |
ITGAL | HPRD; |
interacts with |
JAK1 | HPRD; |
interacts with |
JAK2 | HPRD; |
interacts with |
JAK3 | HPRD; |
interacts with |
LCK | BIOGRID; |
interacts with |
LCK | HPRD; |
interacts with |
LCP2 | HPRD; |
interacts with |
LGALS1 | BIOGRID; |
interacts with |
LGALS1 | HPRD; |
interacts with |
LSM1 | HPRD; |
interacts with |
LYN | BIOGRID; |
interacts with |
LYN | HPRD; |
interacts with |
MBL2 | HPRD; |
interacts with |
PAEP | BIOGRID; |
interacts with |
PAEP | HPRD; |
interacts with |
PLK3 | BIOGRID; |
interacts with |
PPFIA1 | HPRD; |
interacts with |
PPFIBP2 | HPRD; |
interacts with |
PRKCSH | BIOGRID; |
interacts with |
PRKCSH | HPRD; |
interacts with |
PTPN6 | HPRD; |
interacts with |
PTPRCAP | BIOGRID; |
interacts with |
PTPRCAP | HPRD; |
interacts with |
RASA1 | HPRD; |
interacts with |
RNF11 | HPRD; |
interacts with |
SEMA4D | BIOGRID; |
interacts with |
SEMA4D | HPRD; |
interacts with |
SKAP1 | BIOGRID; |
interacts with |
SKAP1 | HPRD; |
interacts with |
SLAMF1 | BIOGRID; |
interacts with |
TYK2 | HPRD; |
interacts with |
ZAP70 | HPRD; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
sequential catalysis |
PTPRC | HUMANCYC; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
CXCL12 | NCI_NATURE; |
reacts with |
CXCR4 | NCI_NATURE; |
reacts with |
PTPRC | NCI_NATURE; |
reacts with |
PTPRC | REACTOME; |
reacts with |
SEMA4D | REACTOME; |