| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 5788 |
Name | PTPRC |
Synonymous | B220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200;protein tyrosine phosphatase, receptor type, C;PTPRC;protein tyrosine phosphatase, receptor type, C |
Definition | CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase, receptor type, c polypeptide|receptor-type tyrosine-protein phosphatase C |
Position | 1q31-q32 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for PTPRC | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
CD45(h) + ATP --> CD45(h){pY} + ADP (phosphorylation) | SKAP55(h) + CD45(h) <==> SKAP55(h):CD45(h) (binding) | SKAP55(m.s.){pY} + CD45(h) <==> SKAP55(m.s.){pY}:CD45(h) (binding) | SKAP55(m.s.) + CD45(h) <==> SKAP55(m.s.):CD45(h) (binding) | CD45(h) + SKAP55(h){pY} <==> CD45(h):SKAP55(h){pY} (binding) | SKAP55(m.s.){pY219}{pY232} + CD45(h) <==> SKAP55(m.s.){pY219}{pY232}:CD45(h) (binding) | Fyn(m.s.) + CD45(h) <==> Fyn(m.s.):CD45(h) (binding) | CD45(h) --> CD69(h) (increase of abundance) | CD45(h) --> FCGR2(h){pY} (decrease of phosphorylation) | CD45(h) --> PLCgamma1(h){pY} (decrease of phosphorylation) | CD45(h) --> PLCgamma2(h){pY} (decrease of phosphorylation) | CD45(h) --> Vav(h){pY} (decrease of phosphorylation) | CD45(h) --> RasGAP(h){pY} (decrease of phosphorylation) | IFNAR1(h) + ZAP-70(h) + Lck(h) + CD45(h) <==> IFNAR1(h):ZAP-70(h):Lck(h):CD45(h) (binding) | CD45(h) + IFNAR1(h) <==> CD45(h):IFNAR1(h) (binding) | PTPRC(h) --> CD45(h) (expression). | MBP(m.s.){pY} --CD45(h)--> p + MBP(m.s.) (dephosphorylation) | Lck(m){pY} --CD45(h)--> p + Lck(m) (dephosphorylation) | EGFR(h){pY} --CD45(h)--> EGFR(h) + p (dephosphorylation) | InsR-beta(h){pY} --CD45(h)--> InsR-beta(h) + p (dephosphorylation) | Myosin-P-light chain(m.s.){pY} --CD45(h)--> p + Myosin-P-light chain(m.s.) (dephosphorylation) | LYZ(m.s.){pY} --CD45(h)--> p + LYZ(m.s.) (dephosphorylation) | Albumin(b){pY} --CD45(h)--> p + Albumin(b) (dephosphorylation) | Jak1(h){pY} --CD45(h)--> p + Jak1(h) (dephosphorylation) | Jak3(h){pY} --CD45(h)--> Jak3(h) + p (dephosphorylation) | PTPRC(h) --> CD45-isoform1(h) (expression). | PTPRC(h) --> CD45-isoform2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for PTPRC | |||
Methylation Profile [Top] | ||
There is no record for PTPRC | ||