Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6502

Name

SKP2

Synonymous

FBL1|FBXL1|FLB1|p45;S-phase kinase-associated protein 2, E3 ubiquitin protein ligase;SKP2;S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Definition

CDK2/cyclin A-associated protein p45|F-box/LRR-repeat protein 1|S-phase kinase-associated protein 2|S-phase kinase-associated protein 2 (p45)|p45skp2

Position

5p13

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ANAPC10REACTOME;

in same component

 ANAPC11REACTOME;

in same component

 ANAPC1REACTOME;

in same component

 ANAPC2REACTOME;

in same component

 ANAPC4REACTOME;

in same component

 ANAPC5REACTOME;

in same component

 ANAPC7REACTOME;

in same component

 CDC16REACTOME;

in same component

 CDC23REACTOME;

in same component

 CDC26REACTOME;

in same component

 CDC27REACTOME;

in same component

 CDK2REACTOME;

in same component

 CDKN1BNCI_NATURE;

in same component

 CKS1BREACTOME;

in same component

 CUL1CELL_MAP;

in same component

 CUL1REACTOME;

in same component

 FOXO1NCI_NATURE;

in same component

 FZR1REACTOME;

in same component

 RB1NCI_NATURE;

in same component

 RBL2REACTOME;

in same component

 RBX1CELL_MAP;

in same component

 SKP1CELL_MAP;

in same component

 SKP1REACTOME;

in same component

 UBE2CREACTOME;

in same component

 UBE2D1REACTOME;

in same component

 UBE2E1REACTOME;

interacts with

 BRCA2BIOGRID;

interacts with

 CCNA1BIOGRID;

interacts with

 CCNA2BIOGRID;

interacts with

 CCNA2HPRD;

interacts with

 CCNE1BIOGRID;

interacts with

 CCNE1HPRD;

interacts with

 CCNT1HPRD;

interacts with

 CDC20HPRD;

interacts with

 CDC34HPRD;

interacts with

 CDC53BIOGRID;

interacts with

 CDK2BIOGRID;

interacts with

 CDK2HPRD;

interacts with

 CDK9BIOGRID;

interacts with

 CDK9HPRD;

interacts with

 CDKN1ABIOGRID;

interacts with

 CDKN1AHPRD;

interacts with

 CDKN1AMINT;

interacts with

 CDKN1BBIOGRID;

interacts with

 CDKN1BHPRD;

interacts with

 CDKN1CBIOGRID;

interacts with

 CDKN1CHPRD;

interacts with

 CDT1BIOGRID;

interacts with

 CDT1HPRD;

interacts with

 CKS1BBIOGRID;

interacts with

 CKS1BMINT;

interacts with

 COPS5BIOGRID;

interacts with

 COPS6BIOGRID;

interacts with

 CSM1BIOGRID;

interacts with

 CUL1BIOGRID;

interacts with

 CUL1HPRD;

interacts with

 CUL1MINT;

interacts with

 CUL4ABIOGRID;

interacts with

 CUL4AHPRD;

interacts with

 DDB1BIOGRID;

interacts with

 DDB1HPRD;

interacts with

 DMA1BIOGRID;

interacts with

 DUSP1BIOGRID;

interacts with

 DUSP1HPRD;

interacts with

 E2F1BIOGRID;

interacts with

 E2F1HPRD;

interacts with

 ECDMINT;

interacts with

 ELF4BIOGRID;

interacts with

 ELF4HPRD;

interacts with

 ERG1BIOGRID;

interacts with

 FOXO1BIOGRID;

interacts with

 FZR1HPRD;

interacts with

 GPS1HPRD;

interacts with

 HEK2BIOGRID;

interacts with

 HRT1BIOGRID;

interacts with

 JJJ1INTACT;

interacts with

 MET14BIOGRID;

interacts with

 MET14MINT;

interacts with

 MLLBIOGRID;

interacts with

 MYBL2BIOGRID;

interacts with

 MYBL2HPRD;

interacts with

 MYCBIOGRID;

interacts with

 MYCHPRD;

interacts with

 NLKBIOGRID;

interacts with

 NLKHPRD;

interacts with

 ORC1BIOGRID;

interacts with

 ORC1HPRD;

interacts with

 PFDN1HPRD;

interacts with

 PSMD9BIOGRID;

interacts with

 RAG2BIOGRID;

interacts with

 RASSF1BIOGRID;

interacts with

 RB1BIOGRID;

interacts with

 RB1HPRD;

interacts with

 RBL2BIOGRID;

interacts with

 RBX1BIOGRID;

interacts with

 RBX1MINT;

interacts with

 RMPHPRD;

interacts with

 RPT2BIOGRID;

interacts with

 RPT4BIOGRID;

interacts with

 RUVBL1HPRD;

interacts with

 RUVBL2HPRD;

interacts with

 RVB1BIOGRID;

interacts with

 SER33BIOGRID;

interacts with

 SER33MINT;

interacts with

 SIS1INTACT;

interacts with

 SKP1BIOGRID;

interacts with

 SKP1HPRD;

interacts with

 SKP1MINT;

interacts with

 SMAD4BIOGRID;

interacts with

 SP1BIOGRID;

interacts with

 SPDYAMINT;

interacts with

 SSA1INTACT;

interacts with

 SSB1INTACT;

interacts with

 SSE1INTACT;

interacts with

 STAP1HPRD;

interacts with

 STI1BIOGRID;

interacts with

 STI1MINT;

interacts with

 TAL1BIOGRID;

interacts with

 TAL1HPRD;

interacts with

 TCF3BIOGRID;

interacts with

 TCF3CELL_MAP;

interacts with

 TCF3HPRD;

interacts with

 TOB1BIOGRID;

interacts with

 TRIM21BIOGRID;

interacts with

 UBI4BIOGRID;

interacts with

 UFD1LBIOGRID;

interacts with

 USP13BIOGRID;

interacts with

 USP18BIOGRID;

interacts with

 WEE1BIOGRID;

interacts with

 WEE1HPRD;

interacts with

 YDJ1INTACT;

interacts with

 YWHABMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 FOXM1NCI_NATURE;

metabolic catalysis

 NOTCH1NCI_NATURE;

metabolic catalysis

 RBPJNCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ANAPC10REACTOME;

reacts with

 ANAPC11REACTOME;

reacts with

 ANAPC1REACTOME;

reacts with

 ANAPC2REACTOME;

reacts with

 ANAPC4REACTOME;

reacts with

 ANAPC5REACTOME;

reacts with

 ANAPC7REACTOME;

reacts with

 CDC16REACTOME;

reacts with

 CDC23REACTOME;

reacts with

 CDC26REACTOME;

reacts with

 CDC27REACTOME;

reacts with

 CDK2REACTOME;

reacts with

 CDKN1BNCI_NATURE;

reacts with

 CKS1BREACTOME;

reacts with

 CUL1REACTOME;

reacts with

 FOXO1NCI_NATURE;

reacts with

 FZR1REACTOME;

reacts with

 RB1NCI_NATURE;

reacts with

 RBL2REACTOME;

reacts with

 SKP1REACTOME;

reacts with

 SKP2NCI_NATURE;

reacts with

 SKP2REACTOME;

reacts with

 UBE2CREACTOME;

reacts with

 UBE2D1REACTOME;

reacts with

 UBE2E1REACTOME;

state change

 CDK2REACTOME;

state change

 CKS1BREACTOME;

state change

 CUL1REACTOME;

state change

 PSMA1REACTOME;

state change

 PSMA2REACTOME;

state change

 PSMA3REACTOME;

state change

 PSMA4REACTOME;

state change

 PSMA5REACTOME;

state change

 PSMA6REACTOME;

state change

 PSMA7REACTOME;

state change

 PSMA8REACTOME;

state change

 PSMB10REACTOME;

state change

 PSMB11REACTOME;

state change

 PSMB1REACTOME;

state change

 PSMB2REACTOME;

state change

 PSMB3REACTOME;

state change

 PSMB4REACTOME;

state change

 PSMB5REACTOME;

state change

 PSMB6REACTOME;

state change

 PSMB7REACTOME;

state change

 PSMB8REACTOME;

state change

 PSMB9REACTOME;

state change

 PSMC1REACTOME;

state change

 PSMC2REACTOME;

state change

 PSMC3REACTOME;

state change

 PSMC4REACTOME;

state change

 PSMC5REACTOME;

state change

 PSMC6REACTOME;

state change

 PSMD10REACTOME;

state change

 PSMD11REACTOME;

state change

 PSMD12REACTOME;

state change

 PSMD13REACTOME;

state change

 PSMD14REACTOME;

state change

 PSMD1REACTOME;

state change

 PSMD2REACTOME;

state change

 PSMD3REACTOME;

state change

 PSMD4REACTOME;

state change

 PSMD5REACTOME;

state change

 PSMD6REACTOME;

state change

 PSMD7REACTOME;

state change

 PSMD8REACTOME;

state change

 PSMD9REACTOME;

state change

 PSME1REACTOME;

state change

 PSME2REACTOME;

state change

 PSME3REACTOME;

state change

 PSME4REACTOME;

state change

 PSMF1REACTOME;

state change

 RBL2REACTOME;

state change

 SKP1REACTOME;

state change

 SKP2REACTOME;

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