General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 7428 |
Name | VHL |
Synonymous | HRCA1|RCA1|VHL1|pVHL;von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase;VHL;von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
Definition | elongin binding protein|protein G7|von Hippel-Lindau disease tumor suppressor |
Position | 3p25.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
CUL2 | NCI_NATURE; |
in same component |
EPAS1 | NCI_NATURE; |
in same component |
HIF1A | NCI_NATURE; |
in same component |
RBX1 | NCI_NATURE; |
in same component |
TCEB1 | NCI_NATURE; |
in same component |
TCEB2 | NCI_NATURE; |
interacts with |
APRT | BIOGRID; |
interacts with |
ATM | BIOGRID; |
interacts with |
ATXN2 | BIOGRID; |
interacts with |
CAB39 | BIOGRID; |
interacts with |
CCDC59 | BIOGRID; |
interacts with |
CCDC82 | BIOGRID; |
interacts with |
CCT3 | BIOGRID; |
interacts with |
CDK2 | BIOGRID; |
interacts with |
CDO1 | BIOGRID; |
interacts with |
CHMP2B | BIOGRID; |
interacts with |
CNTF | BIOGRID; |
interacts with |
CSTB | BIOGRID; |
interacts with |
CSTF3 | BIOGRID; |
interacts with |
CUL2 | BIOGRID; |
interacts with |
CUL2 | HPRD; |
interacts with |
CUL2 | MINT; |
interacts with |
CUL5 | BIOGRID; |
interacts with |
CUL5 | HPRD; |
interacts with |
CYBA | BIOGRID; |
interacts with |
DGKZ | BIOGRID; |
interacts with |
DNAJA3 | BIOGRID; |
interacts with |
DVL2 | BIOGRID; |
interacts with |
EP300 | BIOGRID; |
interacts with |
EPAS1 | BIOGRID; |
interacts with |
EPAS1 | HPRD; |
interacts with |
FLNA | BIOGRID; |
interacts with |
FLNA | HPRD; |
interacts with |
FN1 | BIOGRID; |
interacts with |
FN1 | MINT; |
interacts with |
FSCN1 | BIOGRID; |
interacts with |
FZR1 | INTACT; |
interacts with |
HAS1 | BIOGRID; |
interacts with |
HDAC1 | BIOGRID; |
interacts with |
HDAC2 | BIOGRID; |
interacts with |
HDAC3 | BIOGRID; |
interacts with |
HIF1AN | BIOGRID; |
interacts with |
HIF1AN | HPRD; |
interacts with |
HIF1A | BIOGRID; |
interacts with |
HIF1A | HPRD; |
interacts with |
HIF1A | MINT; |
interacts with |
HIF3A | BIOGRID; |
interacts with |
HIF3A | HPRD; |
interacts with |
HIST1H2BC | BIOGRID; |
interacts with |
HNRNPA2B1 | BIOGRID; |
interacts with |
HNRNPA2B1 | HPRD; |
interacts with |
IARS | BIOGRID; |
interacts with |
IMPDH2 | BIOGRID; |
interacts with |
IREB2 | BIOGRID; |
interacts with |
JMJD1C | BIOGRID; |
interacts with |
KAT2B | BIOGRID; |
interacts with |
KNTC1 | BIOGRID; |
interacts with |
LRRC41 | HPRD; |
interacts with |
MCC | BIOGRID; |
interacts with |
MCM7 | BIOGRID; |
interacts with |
MOBKL3 | BIOGRID; |
interacts with |
MYBBP1A | BIOGRID; |
interacts with |
MYL12A | BIOGRID; |
interacts with |
Myog | BIOGRID; |
interacts with |
NEDD8 | BIOGRID; |
interacts with |
NR4A1 | BIOGRID; |
interacts with |
NR4A2 | HPRD; |
interacts with |
NR4A3 | HPRD; |
interacts with |
OSR1 | BIOGRID; |
interacts with |
PAPSS2 | BIOGRID; |
interacts with |
PFAS | BIOGRID; |
interacts with |
PHF17 | BIOGRID; |
interacts with |
PHF17 | HPRD; |
interacts with |
PIN1 | BIOGRID; |
interacts with |
POLR2A | BIOGRID; |
interacts with |
PPIB | BIOGRID; |
interacts with |
PRKCI | BIOGRID; |
interacts with |
PRKCZ | MINT; |
interacts with |
PSMB1 | BIOGRID; |
interacts with |
PSMB3 | BIOGRID; |
interacts with |
PSMC3 | BIOGRID; |
interacts with |
PSMC3 | HPRD; |
interacts with |
PSMD13 | BIOGRID; |
interacts with |
RAB1B | BIOGRID; |
interacts with |
RASGRP1 | BIOGRID; |
interacts with |
RBX1 | BIOGRID; |
interacts with |
RBX1 | HPRD; |
interacts with |
RHOC | BIOGRID; |
interacts with |
RIT1 | BIOGRID; |
interacts with |
RNF139 | HPRD; |
interacts with |
RPA3 | BIOGRID; |
interacts with |
RPS9 | BIOGRID; |
interacts with |
SAP130 | BIOGRID; |
interacts with |
SAT2 | BIOGRID; |
interacts with |
SOCS1 | HPRD; |
interacts with |
SP1 | HPRD; |
interacts with |
STK16 | BIOGRID; |
interacts with |
TAGLN2 | BIOGRID; |
interacts with |
TARS | BIOGRID; |
interacts with |
TCEB1 | BIOGRID; |
interacts with |
TCEB1 | HPRD; |
interacts with |
TCEB1 | MINT; |
interacts with |
TCEB2 | BIOGRID; |
interacts with |
TCEB2 | HPRD; |
interacts with |
TCEB2 | MINT; |
interacts with |
TCEB3 | BIOGRID; |
interacts with |
TCEB3 | HPRD; |
interacts with |
TGFB1I1 | BIOGRID; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TPT1 | BIOGRID; |
interacts with |
TRIM28 | BIOGRID; |
interacts with |
TXN | BIOGRID; |
interacts with |
USP20 | BIOGRID; |
interacts with |
USP33 | BIOGRID; |
interacts with |
USP33 | HPRD; |
interacts with |
VBP1 | BIOGRID; |
interacts with |
VBP1 | HPRD; |
interacts with |
WSB1 | HPRD; |
interacts with |
ZNF197 | BIOGRID; |
interacts with |
ZNF197 | HPRD; |
interacts with |
ZNF512B | MINT; |
Metabolic Interaction [Top] | ||
There is no record for VHL |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
CUL2 | NCI_NATURE; |
reacts with |
EPAS1 | NCI_NATURE; |
reacts with |
HIF1A | NCI_NATURE; |
reacts with |
RBX1 | NCI_NATURE; |
reacts with |
TCEB1 | NCI_NATURE; |
reacts with |
TCEB2 | NCI_NATURE; |
reacts with |
VHL | NCI_NATURE; |