General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 7520 |
Name | XRCC5 |
Synonymous | KARP-1|KARP1|KU80|KUB2|Ku86|NFIV;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining);XRCC5;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
Definition | 86 kDa subunit of Ku antigen|ATP-dependent DNA helicase 2 subunit 2|ATP-dependent DNA helicase II 80 kDa subunit|CTC box-binding factor 85 kDa subunit|CTC85|CTCBF|DNA repair protein XRCC5|Ku autoantigen, 80kDa|Ku86 autoantigen related protein 1|TLAA|X-ray |
Position | 2q35 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
APLF | NCI_NATURE; |
in same component |
APTX | NCI_NATURE; |
in same component |
BARD1 | NCI_NATURE; |
in same component |
DCLRE1C | NCI_NATURE; |
in same component |
DNTT | NCI_NATURE; |
in same component |
LIG4 | NCI_NATURE; |
in same component |
LIG4 | REACTOME; |
in same component |
NHEJ1 | NCI_NATURE; |
in same component |
PNKP | NCI_NATURE; |
in same component |
POLL | NCI_NATURE; |
in same component |
POLM | NCI_NATURE; |
in same component |
PRKDC | NCI_NATURE; |
in same component |
PRKDC | REACTOME; |
in same component |
TERT | NCI_NATURE; |
in same component |
TP53 | NCI_NATURE; |
in same component |
XRCC4 | NCI_NATURE; |
in same component |
XRCC4 | REACTOME; |
in same component |
XRCC6 | NCI_NATURE; |
in same component |
XRCC6 | REACTOME; |
interacts with |
ACADVL | HPRD; |
interacts with |
ACTB | HPRD; |
interacts with |
ACTG1 | HPRD; |
interacts with |
ACTG2 | HPRD; |
interacts with |
ACTN4 | HPRD; |
interacts with |
ALB | HPRD; |
interacts with |
ANP32B | HPRD; |
interacts with |
APEX1 | BIOGRID; |
interacts with |
APLF | MINT; |
interacts with |
AR | BIOGRID; |
interacts with |
AR | HPRD; |
interacts with |
ATM | HPRD; |
interacts with |
ATP5A1 | INTACT; |
interacts with |
ATR | HPRD; |
interacts with |
BARD1 | BIOGRID; |
interacts with |
BIN1 | BIOGRID; |
interacts with |
BIN1 | HPRD; |
interacts with |
BLZF1 | HPRD; |
interacts with |
BMI1 | BIOGRID; |
interacts with |
BRCA1 | BIOGRID; |
interacts with |
C1QBP | HPRD; |
interacts with |
CAD | INTACT; |
interacts with |
CBX1 | HPRD; |
interacts with |
CBX5 | HPRD; |
interacts with |
CD40 | BIOGRID; |
interacts with |
CD40 | HPRD; |
interacts with |
CDH1 | HPRD; |
interacts with |
CEBPA | HPRD; |
interacts with |
CHAF1A | BIOGRID; |
interacts with |
CHD1L | BIOGRID; |
interacts with |
CHEK1 | BIOGRID; |
interacts with |
COIL | MINT; |
interacts with |
CTNNA1 | HPRD; |
interacts with |
CTNNB1 | HPRD; |
interacts with |
DDX17 | INTACT; |
interacts with |
DDX21 | HPRD; |
interacts with |
DDX3X | INTACT; |
interacts with |
DDX5 | INTACT; |
interacts with |
DEK | HPRD; |
interacts with |
DHX9 | BIOGRID; |
interacts with |
EIF2S1 | HPRD; |
interacts with |
EIF2S1 | INTACT; |
interacts with |
EIF2S2 | HPRD; |
interacts with |
ERG | INTACT; |
interacts with |
ESR1 | BIOGRID; |
interacts with |
ETS1 | INTACT; |
interacts with |
ETV1 | INTACT; |
interacts with |
GBAS | HPRD; |
interacts with |
H2AFX | BIOGRID; |
interacts with |
H2AFX | HPRD; |
interacts with |
H2AFY | BIOGRID; |
interacts with |
H2AFY | HPRD; |
interacts with |
HDLBP | BIOGRID; |
interacts with |
HDLBP | HPRD; |
interacts with |
HIST1H1A | HPRD; |
interacts with |
HIST1H2BC | HPRD; |
interacts with |
HNRNPA2B1 | INTACT; |
interacts with |
HNRNPM | INTACT; |
interacts with |
HNRNPU | INTACT; |
interacts with |
HNRPDL | INTACT; |
interacts with |
HOXB7 | HPRD; |
interacts with |
HOXC4 | HPRD; |
interacts with |
HP1BP3 | HPRD; |
interacts with |
HSF1 | BIOGRID; |
interacts with |
HSF1 | HPRD; |
interacts with |
HSP90AA1 | HPRD; |
interacts with |
HSPA5 | HPRD; |
interacts with |
HSPA6 | HPRD; |
interacts with |
HSPA9 | HPRD; |
interacts with |
HSPD1 | HPRD; |
interacts with |
ILF2 | BIOGRID; |
interacts with |
ILF3 | HPRD; |
interacts with |
KAT2A | BIOGRID; |
interacts with |
KAT2B | HPRD; |
interacts with |
KRT18 | HPRD; |
interacts with |
KRT1 | HPRD; |
interacts with |
KRT8 | HPRD; |
interacts with |
KRT9 | HPRD; |
interacts with |
LIG3 | MINT; |
interacts with |
LIG4 | BIOGRID; |
interacts with |
LIG4 | HPRD; |
interacts with |
LMNA | HPRD; |
interacts with |
MDC1 | HPRD; |
interacts with |
MSX2 | BIOGRID; |
interacts with |
MSX2 | HPRD; |
interacts with |
NAA15 | BIOGRID; |
interacts with |
NAA15 | HPRD; |
interacts with |
NBN | HPRD; |
interacts with |
NCOA6 | BIOGRID; |
interacts with |
NCOA6 | HPRD; |
interacts with |
NDRG1 | HPRD; |
interacts with |
NFKB2 | MINT; |
interacts with |
NHEJ1 | MINT; |
interacts with |
NIPSNAP1 | HPRD; |
interacts with |
NR1H4 | BIOGRID; |
interacts with |
ORC1 | BIOGRID; |
interacts with |
ORC2 | BIOGRID; |
interacts with |
ORC2 | HPRD; |
interacts with |
PARP1 | BIOGRID; |
interacts with |
PARP1 | HPRD; |
interacts with |
PARP1 | INTACT; |
interacts with |
PARP1 | MINT; |
interacts with |
PCBP1 | INTACT; |
interacts with |
PCNA | BIOGRID; |
interacts with |
PCNA | HPRD; |
interacts with |
PDX1 | BIOGRID; |
interacts with |
PHF1 | BIOGRID; |
interacts with |
PIAS4 | MINT; |
interacts with |
PIPOX | HPRD; |
interacts with |
POLA1 | BIOGRID; |
interacts with |
POLA1 | HPRD; |
interacts with |
POLD1 | HPRD; |
interacts with |
POLE | HPRD; |
interacts with |
POLR2A | HPRD; |
interacts with |
POLR2D | BIOGRID; |
interacts with |
POLR2E | BIOGRID; |
interacts with |
POLR2E | HPRD; |
interacts with |
POU2AF1 | HPRD; |
interacts with |
POU2F1 | BIOGRID; |
interacts with |
PPA1 | HPRD; |
interacts with |
PRIM1 | BIOGRID; |
interacts with |
PRKDC | BIOGRID; |
interacts with |
PRKDC | HPRD; |
interacts with |
PRKDC | INTACT; |
interacts with |
PRKDC | MINT; |
interacts with |
PRMT5 | HPRD; |
interacts with |
PRPF8 | INTACT; |
interacts with |
RAN | HPRD; |
interacts with |
RBM14 | BIOGRID; |
interacts with |
RBM14 | HPRD; |
interacts with |
RCC1 | HPRD; |
interacts with |
RECQL | MINT; |
interacts with |
RFC1 | BIOGRID; |
interacts with |
RPA1 | MINT; |
interacts with |
RPLP0 | INTACT; |
interacts with |
RUNX2 | BIOGRID; |
interacts with |
RUNX2 | HPRD; |
interacts with |
SET | HPRD; |
interacts with |
SIRT6 | BIOGRID; |
interacts with |
SPI1 | INTACT; |
interacts with |
SPTAN1 | INTACT; |
interacts with |
SUPT16H | INTACT; |
interacts with |
SUPT5H | HPRD; |
interacts with |
TERF1 | BIOGRID; |
interacts with |
TERF2IP | BIOGRID; |
interacts with |
TERF2IP | HPRD; |
interacts with |
TERF2 | BIOGRID; |
interacts with |
TERT | BIOGRID; |
interacts with |
TERT | HPRD; |
interacts with |
TGM2 | HPRD; |
interacts with |
THRA | BIOGRID; |
interacts with |
THRB | BIOGRID; |
interacts with |
TMPO | INTACT; |
interacts with |
TOP1 | HPRD; |
interacts with |
TOP1 | INTACT; |
interacts with |
TOP1 | MINT; |
interacts with |
TOP2A | BIOGRID; |
interacts with |
TOP2B | HPRD; |
interacts with |
TUBB | INTACT; |
interacts with |
TYK2 | BIOGRID; |
interacts with |
TYK2 | HPRD; |
interacts with |
VAV1 | BIOGRID; |
interacts with |
VAV1 | HPRD; |
interacts with |
WDR77 | HPRD; |
interacts with |
WRN | BIOGRID; |
interacts with |
WRN | HPRD; |
interacts with |
WRN | INTACT; |
interacts with |
XRCC1 | MINT; |
interacts with |
XRCC4 | BIOGRID; |
interacts with |
XRCC4 | MINT; |
interacts with |
XRCC6 | BIOGRID; |
interacts with |
XRCC6 | HPRD; |
interacts with |
XRCC6 | INTACT; |
interacts with |
XRCC6 | MINT; |
Metabolic Interaction [Top] | ||
There is no record for XRCC5 |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
APLF | NCI_NATURE; |
reacts with |
APTX | NCI_NATURE; |
reacts with |
BANF1 | REACTOME; |
reacts with |
BARD1 | NCI_NATURE; |
reacts with |
DCLRE1C | NCI_NATURE; |
reacts with |
DNTT | NCI_NATURE; |
reacts with |
LIG4 | NCI_NATURE; |
reacts with |
LIG4 | REACTOME; |
reacts with |
NHEJ1 | NCI_NATURE; |
reacts with |
PNKP | NCI_NATURE; |
reacts with |
POLL | NCI_NATURE; |
reacts with |
POLM | NCI_NATURE; |
reacts with |
PRKDC | NCI_NATURE; |
reacts with |
PRKDC | REACTOME; |
reacts with |
TERT | NCI_NATURE; |
reacts with |
TP53 | NCI_NATURE; |
reacts with |
XRCC4 | NCI_NATURE; |
reacts with |
XRCC4 | REACTOME; |
reacts with |
XRCC5 | NCI_NATURE; |
reacts with |
XRCC5 | REACTOME; |
reacts with |
XRCC6 | NCI_NATURE; |
reacts with |
XRCC6 | REACTOME; |
state change |
LIG4 | REACTOME; |
state change |
XRCC4 | REACTOME; |
state change |
XRCC5 | REACTOME; |
state change |
XRCC6 | REACTOME; |