Entrez Gene

Basic Information
Gene ID	7520
Name	XRCC5
Synonymous	KARP-1\|KARP1\|KU80\|KUB2\|Ku86\|NFIV;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining);XRCC5;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Definition	86 kDa subunit of Ku antigen\|ATP-dependent DNA helicase 2 subunit 2\|ATP-dependent DNA helicase II 80 kDa subunit\|CTC box-binding factor 85 kDa subunit\|CTC85\|CTCBF\|DNA repair protein XRCC5\|Ku autoantigen, 80kDa\|Ku86 autoantigen related protein 1\|TLAA\|X-ray
Position	2q35
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Ku80(h) + Polm(h) <==> Ku80(h):Polm(h) (binding)
Ku80(h) + Polm(h) <==> Ku80(h):Polm(h) (binding)
ASC-2(h) + Ku80(h) <==> ASC-2(h):Ku80(h) (binding)
Ku70(h) + Ku80(h) <==> Ku70(h):Ku80(h) (binding)
Ku80(h) + acetyl-CoA --> Ku80(h){aceK} + CoA (acetylation)
TERF2IP(h) + TRF2(h) + Mre11(h) + Ku70(h) + Ku80(h) + PARP(h) + Rad50(h) <==> TERF2IP(h):TRF2(h):Mre11(h):Ku70(h):Ku80(h):PARP(h):Rad50(h) (binding)
Ku80(h) + TRF2(h) <==> Ku80(h):TRF2(h) (binding)
Ku80(h) + TERF2IP(h) <==> Ku80(h):TERF2IP(h) (binding)
Ku80(h) + AR-isoform1(h) <==> Ku80(h):AR-isoform1(h) (binding)
DNA-PKcs(h) + Ku80(h) + Ku70(h) + AR(h) <==> DNA-PKcs(h):Ku80(h):Ku70(h):AR(h) (binding)
Ku80(h) --> ATP7B(h) (DNA binding).
Ku80(h) --> CYP1A1(h) (DNA binding).
TCF-4(h) + Ku80(h) <==> TCF-4(h):Ku80(h) (binding)
Ku80(h) + PARP(h) <==> Ku80(h):PARP(h) (binding)
Ku80(h) + CAPER-alpha(h) <==> Ku80(h):CAPER-alpha(h) (binding)
Ku80(h) --> NFKB1(h) (DNA binding).
Ku80(h) + ZEB1(h) <==> Ku80(h):ZEB1(h) (binding)
Ku80(h) --> XDH(h) (DNA binding).
Ku80(h) --> DIO1(h) (DNA binding).
XRCC5(h) --> Ku80(h) (expression).
PCNA(h) + Ku80(h) <==> PCNA(h):Ku80(h) (binding)
XRCC5(h) --> Ku80(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for XRCC5