Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8651

Name

SOCS1

Synonymous

CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP3;suppressor of cytokine signaling 1;SOCS1;suppressor of cytokine signaling 1

Definition

JAK binding protein|JAK-binding protein|STAT induced SH3 protein 1|STAT-induced STAT inhibitor 1|TIP-3|Tec-interacting protein 3|cytokine-inducible SH2 protein 1

Position

16p13.13

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 IFNGR1NCI_NATURE;

in same component

 IFNGNCI_NATURE;

in same component

 IL12ANCI_NATURE;

in same component

 IL12BNCI_NATURE;

in same component

 IL12RB1NCI_NATURE;

in same component

 IL12RB2NCI_NATURE;

in same component

 IL2RBNCI_NATURE;

in same component

 IL2RGNCI_NATURE;

in same component

 JAK1NCI_NATURE;

in same component

 JAK2NCI_NATURE;

in same component

 JAK3NCI_NATURE;

in same component

 KITREACTOME;

in same component

 LCKNCI_NATURE;

in same component

 TYK2NCI_NATURE;

in same component

 VAV1NCI_NATURE;

interacts with

 ALKBIOGRID;

interacts with

 AXLHPRD;

interacts with

 COMMD1BIOGRID;

interacts with

 COMMD1HPRD;

interacts with

 COMMD1MINT;

interacts with

 CRKBIOGRID;

interacts with

 CSF1RBIOGRID;

interacts with

 CSF1HPRD;

interacts with

 CUL2MINT;

interacts with

 CUL5HPRD;

interacts with

 CXCR4HPRD;

interacts with

 EGFRBIOGRID;

interacts with

 EGFRCELL_MAP;

interacts with

 EGFRHPRD;

interacts with

 ERBB2MINT;

interacts with

 FLT3BIOGRID;

interacts with

 FLT3HPRD;

interacts with

 FYNBIOGRID;

interacts with

 FYNHPRD;

interacts with

 GHRBIOGRID;

interacts with

 GHRHPRD;

interacts with

 IFNGR1HPRD;

interacts with

 IGF1RBIOGRID;

interacts with

 IGF1RHPRD;

interacts with

 IL2RBBIOGRID;

interacts with

 IL2RBHPRD;

interacts with

 INSRHPRD;

interacts with

 IRS1BIOGRID;

interacts with

 IRS1HPRD;

interacts with

 IRS2BIOGRID;

interacts with

 IRS2HPRD;

interacts with

 ITKBIOGRID;

interacts with

 ITKHPRD;

interacts with

 JAK1HPRD;

interacts with

 JAK2BIOGRID;

interacts with

 JAK2HPRD;

interacts with

 JAK2MINT;

interacts with

 JAK3HPRD;

interacts with

 KITBIOGRID;

interacts with

 KITCELL_MAP;

interacts with

 KITHPRD;

interacts with

 LRRC41HPRD;

interacts with

 MAP3K5BIOGRID;

interacts with

 MAP3K5MINT;

interacts with

 MPLBIOGRID;

interacts with

 MPLHPRD;

interacts with

 NCK1BIOGRID;

interacts with

 NCK1HPRD;

interacts with

 PDGFRBHPRD;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R2HPRD;

interacts with

 PIM2HPRD;

interacts with

 RBX1HPRD;

interacts with

 RBX1MINT;

interacts with

 RELABIOGRID;

interacts with

 RELAHPRD;

interacts with

 RELAMINT;

interacts with

 SOCS2BIOGRID;

interacts with

 TCEB1BIOGRID;

interacts with

 TCEB1HPRD;

interacts with

 TCEB1MINT;

interacts with

 TCEB2HPRD;

interacts with

 TCEB2MINT;

interacts with

 TCEB3BIOGRID;

interacts with

 TCEB3HPRD;

interacts with

 TECBIOGRID;

interacts with

 TECHPRD;

interacts with

 TIRAPHPRD;

interacts with

 TRIM8HPRD;

interacts with

 TUBA3CMINT;

interacts with

 VAV1BIOGRID;

interacts with

 Vav1CELL_MAP;

interacts with

 VAV1HPRD;

interacts with

 VAV2BIOGRID;

interacts with

 VAV2CELL_MAP;

interacts with

 VAV2HPRD;

interacts with

 VHLHPRD;

interacts with

 WSB1HPRD;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

 ETS1NCI_NATURE;

metabolic catalysis

 IRF1NCI_NATURE;

metabolic catalysis

 PIAS4NCI_NATURE;

metabolic catalysis

 STAT1NCI_NATURE;

metabolic catalysis

 STAT6NCI_NATURE;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 IFNGR1NCI_NATURE;

reacts with

 IFNGNCI_NATURE;

reacts with

 IL12ANCI_NATURE;

reacts with

 IL12BNCI_NATURE;

reacts with

 IL12RB1NCI_NATURE;

reacts with

 IL12RB2NCI_NATURE;

reacts with

 JAK1NCI_NATURE;

reacts with

 JAK2NCI_NATURE;

reacts with

 KITREACTOME;

reacts with

 SOCS1NCI_NATURE;

reacts with

 SOCS1REACTOME;

reacts with

 TYK2NCI_NATURE;

reacts with

 VAV1NCI_NATURE;

state change

 KITLGNCI_NATURE;

state change

 KITNCI_NATURE;

')