Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

867

Name

CBL

Synonymous

C-CBL|CBL2|FRA11B|NSLL|RNF55;Cbl proto-oncogene, E3 ubiquitin protein ligase;CBL;Cbl proto-oncogene, E3 ubiquitin protein ligase

Definition

Cas-Br-M (murine) ecotropic retroviral transforming sequence|E3 ubiquitin-protein ligase CBL|RING finger protein 55|casitas B-lineage lymphoma proto-oncogene|fragile site, folic acid type, rare, fra(11)(q23.3)|oncogene CBL2|proto-oncogene c-Cbl|signal tra

Position

11q23.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 AP2B1REACTOME;

in same component

 AP2M1REACTOME;

in same component

 AP2S1REACTOME;

in same component

 ARHGEF7NCI_NATURE;

in same component

 ARHGEF7REACTOME;

in same component

 B2MNCI_NATURE;

in same component

 BCAR1NCI_NATURE;

in same component

 BLNKREACTOME;

in same component

 CD247NCI_NATURE;

in same component

 CD2APNCI_NATURE;

in same component

 CD3DNCI_NATURE;

in same component

 CD3ENCI_NATURE;

in same component

 CD3GNCI_NATURE;

in same component

 CD4NCI_NATURE;

in same component

 CD8ANCI_NATURE;

in same component

 CD8BNCI_NATURE;

in same component

 CDC42NCI_NATURE;

in same component

 CDC42REACTOME;

in same component

 CRKLNCI_NATURE;

in same component

 CSF1RNCI_NATURE;

in same component

 EGFNCI_NATURE;

in same component

 EGFREACTOME;

in same component

 EGFRNCI_NATURE;

in same component

 EGFRREACTOME;

in same component

 EPN1REACTOME;

in same component

 EPS15REACTOME;

in same component

 EPS15L1REACTOME;

in same component

 FLT1NCI_NATURE;

in same component

 FRS2NCI_NATURE;

in same component

 FRS2REACTOME;

in same component

 GNG2NCI_NATURE;

in same component

 HGSREACTOME;

in same component

 HLA-ANCI_NATURE;

in same component

 HLA-DRANCI_NATURE;

in same component

 HLA-DRB1NCI_NATURE;

in same component

 ITGAVNCI_NATURE;

in same component

 ITGB3NCI_NATURE;

in same component

 KDRNCI_NATURE;

in same component

 KITCELL_MAP;

in same component

 LCKNCI_NATURE;

in same component

 PDGFBNCI_NATURE;

in same component

 PDGFRBNCI_NATURE;

in same component

 PIK3CGNCI_NATURE;

in same component

 PIK3R6NCI_NATURE;

in same component

 PTPN11REACTOME;

in same component

 RAPGEF1NCI_NATURE;

in same component

 RAPGEF1REACTOME;

in same component

 SDC2NCI_NATURE;

in same component

 SH2B2NCI_NATURE;

in same component

 SH3GL2NCI_NATURE;

in same component

 SH3GL2REACTOME;

in same component

 SH3KBP1NCI_NATURE;

in same component

 SH3KBP1REACTOME;

in same component

 SHC1NCI_NATURE;

in same component

 SLA2NCI_NATURE;

in same component

 SORBS1NCI_NATURE;

in same component

 SOS1NCI_NATURE;

in same component

 SPRY2NCI_NATURE;

in same component

 SPRY2REACTOME;

in same component

 VAV1NCI_NATURE;

in same component

 VAV1REACTOME;

in same component

 VEGFANCI_NATURE;

in same component

 ZAP70NCI_NATURE;

interacts with

 ABL1BIOGRID;

interacts with

 ABL1MINT;

interacts with

 ACTA1BIOGRID;

interacts with

 ACTA2MINT;

interacts with

 ACTBBIOGRID;

interacts with

 ACTBMINT;

interacts with

 ACTG1MINT;

interacts with

 ACTG2BIOGRID;

interacts with

 ACTN2MINT;

interacts with

 ACTN3MINT;

interacts with

 ANKRD18AMINT;

interacts with

 ARHGAP20INTACT;

interacts with

 ARHGEF7BIOGRID;

interacts with

 ARHGEF7MINT;

interacts with

 ASAP1HPRD;

interacts with

 ASAP1INTACT;

interacts with

 ASAP1MINT;

interacts with

 ASAP2INTACT;

interacts with

 ATP5A1MINT;

interacts with

 AXLBIOGRID;

interacts with

 AXLHPRD;

interacts with

 BANK1MINT;

interacts with

 BLKHPRD;

interacts with

 BLKMINT;

interacts with

 BTKBIOGRID;

interacts with

 BTKHPRD;

interacts with

 C11orf84INTACT;

interacts with

 CACNA1SMINT;

interacts with

 CALM1MINT;

interacts with

 CAPN1HPRD;

interacts with

 CBLBINTACT;

interacts with

 CD19HPRD;

interacts with

 CD247BIOGRID;

interacts with

 CD2APBIOGRID;

interacts with

 CD2APHPRD;

interacts with

 CD2APINTACT;

interacts with

 CD2APMINT;

interacts with

 CD40HPRD;

interacts with

 CD5BIOGRID;

interacts with

 CD5HPRD;

interacts with

 CDC42BIOGRID;

interacts with

 CDKL2HPRD;

interacts with

 CEP250MINT;

interacts with

 CRKBIOGRID;

interacts with

 CrkCELL_MAP;

interacts with

 CRKHPRD;

interacts with

 CRKMINT;

interacts with

 CRKLBIOGRID;

interacts with

 CRKLCELL_MAP;

interacts with

 CRKLHPRD;

interacts with

 CRKLMINT;

interacts with

 CSF1BIOGRID;

interacts with

 CSF1RBIOGRID;

interacts with

 CSKBIOGRID;

interacts with

 CSKINTACT;

interacts with

 CSRP1INTACT;

interacts with

 DESMINT;

interacts with

 DIAPH1INTACT;

interacts with

 DNM1INTACT;

interacts with

 DOCK4INTACT;

interacts with

 DOCK5INTACT;

interacts with

 EEF1A1BIOGRID;

interacts with

 EGFRBIOGRID;

interacts with

 EGFRCELL_MAP;

interacts with

 EGFRHPRD;

interacts with

 EGFRINTACT;

interacts with

 EGFRMINT;

interacts with

 EIF5BHPRD;

interacts with

 ELMO2INTACT;

interacts with

 EPHA2HPRD;

interacts with

 EPHA8BIOGRID;

interacts with

 EPHB6HPRD;

interacts with

 EPORHPRD;

interacts with

 EPS15L1INTACT;

interacts with

 ERRFI1INTACT;

interacts with

 F2RL1HPRD;

interacts with

 F2RL1INTACT;

interacts with

 FAM59AINTACT;

interacts with

 FAM59BINTACT;

interacts with

 FCGR1AMINT;

interacts with

 FCGR2ABIOGRID;

interacts with

 FGD6INTACT;

interacts with

 FGFR2HPRD;

interacts with

 FGRBIOGRID;

interacts with

 FLOT1BIOGRID;

interacts with

 FLT1MINT;

interacts with

 FNBP1HPRD;

interacts with

 FRS2BIOGRID;

interacts with

 FRS2HPRD;

interacts with

 FRS2INTACT;

interacts with

 FYBHPRD;

interacts with

 FYNBIOGRID;

interacts with

 FYNHPRD;

interacts with

 FynMINT;

interacts with

 FYNMINT;

interacts with

 GAB2INTACT;

interacts with

 GAPDHBIOGRID;

interacts with

 GAPVD1BIOGRID;

interacts with

 GIT1INTACT;

interacts with

 Grap2BIOGRID;

interacts with

 Grb2MINT;

interacts with

 H1F0MINT;

interacts with

 H2AFXMINT;

interacts with

 HCKBIOGRID;

interacts with

 HCKHPRD;

interacts with

 HDGFRP3INTACT;

interacts with

 HGSINTACT;

interacts with

 HIST1H1CMINT;

interacts with

 HIST1H1DMINT;

interacts with

 HIST1H1TMINT;

interacts with

 HIST1H2AGMINT;

interacts with

 HIST1H2BDMINT;

interacts with

 HNRNPA2B1MINT;

interacts with

 HNRNPCMINT;

interacts with

 HSPA4BIOGRID;

interacts with

 HSPA5BIOGRID;

interacts with

 HUNKINTACT;

interacts with

 IGF1RBIOGRID;

interacts with

 IGF1RHPRD;

interacts with

 IGF2BP1INTACT;

interacts with

 INPPL1BIOGRID;

interacts with

 INPPL1HPRD;

interacts with

 INPPL1INTACT;

interacts with

 INSRHPRD;

interacts with

 IRS1INTACT;

interacts with

 IRS2INTACT;

interacts with

 IRS4INTACT;

interacts with

 ITCHHPRD;

interacts with

 ITCHMINT;

interacts with

 ITGA5BIOGRID;

interacts with

 ITKBIOGRID;

interacts with

 ITKHPRD;

interacts with

 ITSN1BIOGRID;

interacts with

 ITSN1MINT;

interacts with

 KDRBIOGRID;

interacts with

 KDRHPRD;

interacts with

 KHDRBS1HPRD;

interacts with

 KHDRBS1INTACT;

interacts with

 KITBIOGRID;

interacts with

 KITCELL_MAP;

interacts with

 KITHPRD;

interacts with

 KITNCI_NATURE;

interacts with

 KITLGNCI_NATURE;

interacts with

 KRT17MINT;

interacts with

 KRT18BIOGRID;

interacts with

 KRT18HPRD;

interacts with

 KRT18MINT;

interacts with

 KRT8MINT;

interacts with

 LAT2HPRD;

interacts with

 LATHPRD;

interacts with

 LCKBIOGRID;

interacts with

 LCKHPRD;

interacts with

 LckMINT;

interacts with

 LCKMINT;

interacts with

 LCP2BIOGRID;

interacts with

 LCP2HPRD;

interacts with

 LCP2MINT;

interacts with

 LMNAMINT;

interacts with

 LRIG1BIOGRID;

interacts with

 LTKBIOGRID;

interacts with

 LYNBIOGRID;

interacts with

 LYNHPRD;

interacts with

 LYNMINT;

interacts with

 MAP4K5INTACT;

interacts with

 MAPK8MINT;

interacts with

 METBIOGRID;

interacts with

 METHPRD;

interacts with

 METMINT;

interacts with

 MST1RBIOGRID;

interacts with

 MST1RMINT;

interacts with

 MYCBPINTACT;

interacts with

 MYH11MINT;

interacts with

 MYH13MINT;

interacts with

 MYH2MINT;

interacts with

 MYH3MINT;

interacts with

 MYH7MINT;

interacts with

 MYH9BIOGRID;

interacts with

 MYH9MINT;

interacts with

 MYL12AMINT;

interacts with

 MYL3MINT;

interacts with

 MYLK2MINT;

interacts with

 MYO1CBIOGRID;

interacts with

 NCK1BIOGRID;

interacts with

 NCK1HPRD;

interacts with

 NCK1MINT;

interacts with

 NCKAP1INTACT;

interacts with

 NgfrBIOGRID;

interacts with

 NISCHINTACT;

interacts with

 NOTCH1BIOGRID;

interacts with

 NOTCH1HPRD;

interacts with

 ODR4INTACT;

interacts with

 OSTF1HPRD;

interacts with

 PDGFRABIOGRID;

interacts with

 PDGFRAHPRD;

interacts with

 PdgfrbBIOGRID;

interacts with

 PDGFRBHPRD;

interacts with

 PDGFRBMINT;

interacts with

 PEAK1INTACT;

interacts with

 PIK3AP1INTACT;

interacts with

 PIK3C2BINTACT;

interacts with

 PIK3CABIOGRID;

interacts with

 PIK3CAINTACT;

interacts with

 PIK3CBINTACT;

interacts with

 Pik3r1BIOGRID;

interacts with

 PIK3R1BIOGRID;

interacts with

 PIK3R1CELL_MAP;

interacts with

 PIK3R1HPRD;

interacts with

 PIK3R1INTACT;

interacts with

 Pik3r1MINT;

interacts with

 PIK3R1MINT;

interacts with

 PIK3R2BIOGRID;

interacts with

 PIK3R2CELL_MAP;

interacts with

 PIK3R2HPRD;

interacts with

 PIK3R2INTACT;

interacts with

 PIK3R3INTACT;

interacts with

 PLCG1BIOGRID;

interacts with

 PPM1BINTACT;

interacts with

 PPP1CAINTACT;

interacts with

 PPP5CINTACT;

interacts with

 PRKCAHPRD;

interacts with

 PSTPIP2INTACT;

interacts with

 PTK2BBIOGRID;

interacts with

 PTK2BHPRD;

interacts with

 PTPLAD1INTACT;

interacts with

 PTPN11BIOGRID;

interacts with

 PTPN11HPRD;

interacts with

 PTPN11INTACT;

interacts with

 PTPN12INTACT;

interacts with

 PTPN22HPRD;

interacts with

 PTPN6BIOGRID;

interacts with

 PTPN6HPRD;

interacts with

 PXNBIOGRID;

interacts with

 RADILINTACT;

interacts with

 RALYMINT;

interacts with

 RAPGEF1HPRD;

interacts with

 RPS3MINT;

interacts with

 SCN5AHPRD;

interacts with

 SFNMINT;

interacts with

 SH2B2BIOGRID;

interacts with

 SH2B2HPRD;

interacts with

 SH2B2MINT;

interacts with

 SH2D5INTACT;

interacts with

 SH3BP2BIOGRID;

interacts with

 SH3BP2MINT;

interacts with

 SH3GL2BIOGRID;

interacts with

 SH3GL2HPRD;

interacts with

 SH3GL2MINT;

interacts with

 SH3GL3BIOGRID;

interacts with

 SH3GL3HPRD;

interacts with

 SH3KBP1BIOGRID;

interacts with

 SH3KBP1CELL_MAP;

interacts with

 SH3KBP1HPRD;

interacts with

 SH3KBP1MINT;

interacts with

 SH3PXD2AINTACT;

interacts with

 SH3PXD2BINTACT;

interacts with

 SHC1BIOGRID;

interacts with

 SHC1CELL_MAP;

interacts with

 SHC1HPRD;

interacts with

 SHC1INTACT;

interacts with

 SHC1MINT;

interacts with

 SIRPAINTACT;

interacts with

 SLA2BIOGRID;

interacts with

 SLA2HPRD;

interacts with

 SLABIOGRID;

interacts with

 SLAHPRD;

interacts with

 SLAIN2INTACT;

interacts with

 SLC25A13INTACT;

interacts with

 SLC25A5INTACT;

interacts with

 SLC25A6INTACT;

interacts with

 SNX18HPRD;

interacts with

 SORBS1BIOGRID;

interacts with

 SORBS1HPRD;

interacts with

 SORBS2BIOGRID;

interacts with

 SOS1INTACT;

interacts with

 SOS2INTACT;

interacts with

 SPRED2MINT;

interacts with

 SPRY1MINT;

interacts with

 SPRY2BIOGRID;

interacts with

 SPRY2HPRD;

interacts with

 SPRY2MINT;

interacts with

 SPRY4BIOGRID;

interacts with

 SPRY4MINT;

interacts with

 SRCBIOGRID;

interacts with

 SRCHPRD;

interacts with

 SRCMINT;

interacts with

 STAMBPINTACT;

interacts with

 STAP2BIOGRID;

interacts with

 STAT5AHPRD;

interacts with

 STAT5BHPRD;

interacts with

 STSMINT;

interacts with

 SYKBIOGRID;

interacts with

 SYKHPRD;

interacts with

 SYKMINT;

interacts with

 SYNJ1INTACT;

interacts with

 TECINTACT;

interacts with

 TGIF2LYMINT;

interacts with

 TLN1BIOGRID;

interacts with

 TNFRSF10ABIOGRID;

interacts with

 TNFRSF10BBIOGRID;

interacts with

 TNFRSF11AHPRD;

interacts with

 TPM1MINT;

interacts with

 TRAF6HPRD;

interacts with

 TSC2MINT;

interacts with

 TSG101INTACT;

interacts with

 TTNMINT;

interacts with

 TTYH2INTACT;

interacts with

 TUBB2AMINT;

interacts with

 TYK2BIOGRID;

interacts with

 TYK2HPRD;

interacts with

 UBA1BIOGRID;

interacts with

 UBASH3ABIOGRID;

interacts with

 UBASH3BBIOGRID;

interacts with

 UBASH3BHPRD;

interacts with

 UBE2D1BIOGRID;

interacts with

 UBE2D2BIOGRID;

interacts with

 UBE2D2HPRD;

interacts with

 UBE2G1HPRD;

interacts with

 UBE2L3BIOGRID;

interacts with

 UBE2L3HPRD;

interacts with

 UBE2L3MINT;

interacts with

 UBE2MBIOGRID;

interacts with

 UBE4BBIOGRID;

interacts with

 USP42MINT;

interacts with

 VASPMINT;

interacts with

 VAV1BIOGRID;

interacts with

 VAV1HPRD;

interacts with

 VAV1MINT;

interacts with

 VAV2HPRD;

interacts with

 VAV2MINT;

interacts with

 VAV3INTACT;

interacts with

 VIMBIOGRID;

interacts with

 VIMMINT;

interacts with

 WASLINTACT;

interacts with

 WDR44INTACT;

interacts with

 WDR6INTACT;

interacts with

 WDR77INTACT;

interacts with

 WIPF1INTACT;

interacts with

 WIPF2INTACT;

interacts with

 WIPF3INTACT;

interacts with

 YWHABBIOGRID;

interacts with

 YWHABHPRD;

interacts with

 YWHABINTACT;

interacts with

 YWHABMINT;

interacts with

 YWHAEINTACT;

interacts with

 YWHAEMINT;

interacts with

 YWHAGHPRD;

interacts with

 YWHAGINTACT;

interacts with

 YWHAGMINT;

interacts with

 YWHAHINTACT;

interacts with

 YWHAHMINT;

interacts with

 YWHAQBIOGRID;

interacts with

 YWHAQHPRD;

interacts with

 YWHAQINTACT;

interacts with

 YWHAQMINT;

interacts with

 YWHAZBIOGRID;

interacts with

 YWHAZHPRD;

interacts with

 YWHAZINTACT;

interacts with

 YWHAZMINT;

interacts with

 ZAP70BIOGRID;

interacts with

 ZAP70HPRD;

Metabolic Interaction   [Top]

There is no record for CBL

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 AP2B1REACTOME;

reacts with

 AP2M1REACTOME;

reacts with

 AP2S1REACTOME;

reacts with

 ARHGEF7NCI_NATURE;

reacts with

 ARHGEF7REACTOME;

reacts with

 B2MNCI_NATURE;

reacts with

 BCAR1NCI_NATURE;

reacts with

 BLNKREACTOME;

reacts with

 CBLNCI_NATURE;

reacts with

 CBLREACTOME;

reacts with

 CD247NCI_NATURE;

reacts with

 CD2APNCI_NATURE;

reacts with

 CD3DNCI_NATURE;

reacts with

 CD3ENCI_NATURE;

reacts with

 CD3GNCI_NATURE;

reacts with

 CD4NCI_NATURE;

reacts with

 CD8ANCI_NATURE;

reacts with

 CD8BNCI_NATURE;

reacts with

 CDC42NCI_NATURE;

reacts with

 CDC42REACTOME;

reacts with

 CRKLNCI_NATURE;

reacts with

 CSF1RNCI_NATURE;

reacts with

 EGFNCI_NATURE;

reacts with

 EGFREACTOME;

reacts with

 EGFRNCI_NATURE;

reacts with

 EGFRREACTOME;

reacts with

 EPN1REACTOME;

reacts with

 EPS15REACTOME;

reacts with

 EPS15L1REACTOME;

reacts with

 FLT1NCI_NATURE;

reacts with

 FRS2NCI_NATURE;

reacts with

 FRS2REACTOME;

reacts with

 GNG2NCI_NATURE;

reacts with

 GRAP2NCI_NATURE;

reacts with

 HGSREACTOME;

reacts with

 HLA-ANCI_NATURE;

reacts with

 HLA-DRANCI_NATURE;

reacts with

 HLA-DRB1NCI_NATURE;

reacts with

 ITGAVNCI_NATURE;

reacts with

 ITGB3NCI_NATURE;

reacts with

 ITKNCI_NATURE;

reacts with

 KDRNCI_NATURE;

reacts with

 LCKNCI_NATURE;

reacts with

 LCP2NCI_NATURE;

reacts with

 PDGFBNCI_NATURE;

reacts with

 PDGFRBNCI_NATURE;

reacts with

 PIK3CGNCI_NATURE;

reacts with

 PIK3R6NCI_NATURE;

reacts with

 PLCG1NCI_NATURE;

reacts with

 PPP2R1AREACTOME;

reacts with

 PTPN11REACTOME;

reacts with

 RAPGEF1NCI_NATURE;

reacts with

 RAPGEF1REACTOME;

reacts with

 SDC2NCI_NATURE;

reacts with

 SH2B2NCI_NATURE;

reacts with

 SH3GL2REACTOME;

reacts with

 SH3KBP1REACTOME;

reacts with

 SHC1NCI_NATURE;

reacts with

 SLA2NCI_NATURE;

reacts with

 SORBS1NCI_NATURE;

reacts with

 SOS1NCI_NATURE;

reacts with

 SPRY2NCI_NATURE;

reacts with

 SPRY2REACTOME;

reacts with

 VAV1NCI_NATURE;

reacts with

 VAV1REACTOME;

reacts with

 VEGFANCI_NATURE;

reacts with

 ZAP70NCI_NATURE;

state change

 CBLREACTOME;

state change

 CD247NCI_NATURE;

state change

 CD3DNCI_NATURE;

state change

 CD3ENCI_NATURE;

state change

 CD3GNCI_NATURE;

state change

 CD4NCI_NATURE;

state change

 CDC42REACTOME;

state change

 CSF1NCI_NATURE;

state change

 DNM2NCI_NATURE;

state change

 EFNA1NCI_NATURE;

state change

 EGFNCI_NATURE;

state change

 EGFREACTOME;

state change

 EGFRNCI_NATURE;

state change

 EGFRREACTOME;

state change

 EPN1REACTOME;

state change

 EPONCI_NATURE;

state change

 EPORNCI_NATURE;

state change

 EPS15NCI_NATURE;

state change

 EPS15REACTOME;

state change

 EPS15L1REACTOME;

state change

 FCER1ANCI_NATURE;

state change

 FCER1GNCI_NATURE;

state change

 FRS2REACTOME;

state change

 HGSREACTOME;

state change

 HLA-DRANCI_NATURE;

state change

 HLA-DRB1NCI_NATURE;

state change

 IFNGNCI_NATURE;

state change

 IFNGR1NCI_NATURE;

state change

 IGHENCI_NATURE;

state change

 IL2RGNCI_NATURE;

state change

 IL4NCI_NATURE;

state change

 IL4RNCI_NATURE;

state change

 INSNCI_NATURE;

state change

 INSRNCI_NATURE;

state change

 IRS1NCI_NATURE;

state change

 ITSN1NCI_NATURE;

state change

 JAK1NCI_NATURE;

state change

 JAK2NCI_NATURE;

state change

 JAK3NCI_NATURE;

state change

 KDRNCI_NATURE;

state change

 LCKNCI_NATURE;

state change

 LRIG1NCI_NATURE;

state change

 LYNNCI_NATURE;

state change

 MS4A2NCI_NATURE;

state change

 MYOFNCI_NATURE;

state change

 PTPN11REACTOME;

state change

 SH3GL2REACTOME;

state change

 SH3KBP1REACTOME;

state change

 SPRY2REACTOME;

state change

 SYKNCI_NATURE;

state change

 ZAP70NCI_NATURE;

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