Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

c.725C>T; p.A242V; 9:121313995-121313995

c.699C>T; p.T233T; 9:121313969-121313969

c.2114T>C; p.F705S; 9:121332521-121332521

c.1891G>A; p.E631K; 9:121329241-121329241

c.2167G>T; p.D723Y; 9:121332574-121332574

c.449C>T; p.T150I; 9:121310781-121310781

c.449C>T; p.T150I; 9:121310781-121310781

c.2113T>C; p.F705L; 9:121332520-121332520

c.1932G>T; p.T644T; 9:121329282-121329282

c.1116C>T; p.D372D; 9:121318805-121318805

c.514-2A>T; p.?; 9:121312337-121312337

c.2115T>C; p.F705F; 9:121332522-121332522

c.2030A>G; p.K677R; 9:121332437-121332437

c.175T>C; p.Y59H; 9:121302146-121302146

c.486C>T; p.G162G; 9:121310818-121310818

c.486C>T; p.G162G; 9:121310818-121310818

c.76G>A; p.D26N; 9:121302047-121302047

c.76G>A; p.D26N; 9:121302047-121302047

c.19G>A; p.E7K; 9:121301990-121301990

c.123C>T; p.G41G; 9:121302094-121302094

c.123C>T; p.G41G; 9:121302094-121302094

c.1512C>T; p.G504G; 9:121326607-121326607

c.903G>A; p.T301T; 9:121318422-121318422

c.1879C>T; p.R627C; 9:121329007-121329007

c.191G>C; p.W64S; 9:121302162-121302162

c.1928C>T; p.A643V; 9:121329278-121329278

c.1191+1G>A; p.?; 9:121318881-121318881

c.1357G>A; p.A453T; 9:121324585-121324585

c.2068C>T; p.R690W; 9:121332475-121332475

c.243C>T; p.T81T; 9:121302957-121302957

c.1498A>C; p.T500P; 9:121326593-121326593

c.1079C>T; p.S360F; 9:121318768-121318768

c.597C>T; p.N199N; 9:121312422-121312422

c.557G>A; p.R186K; 9:121312382-121312382

c.2032C>T; p.R678W; 9:121332439-121332439

c.429G>A; p.G143G; 9:121310761-121310761

c.2182G>C; p.E728Q; 9:121332589-121332589

c.2182G>C; p.E728Q; 9:121332589-121332589

c.1036C>T; p.R346W; 9:121318725-121318725

c.985C>T; p.L329F; 9:121318674-121318674

c.985C>T; p.L329F; 9:121318674-121318674

c.1036C>T; p.R346W; 9:121318725-121318725

c.964A>T; p.K322*; 9:121318483-121318483

c.385G>A; p.V129I; 9:121310717-121310717

c.799G>A; p.E267K; 9:121317131-121317131

c.2086G>A; p.V696M; 9:121332493-121332493

c.1261G>T; p.D421Y; 9:121321337-121321337

c.450C>T; p.T150T; 9:121310782-121310782

c.879C>T; p.V293V; 9:121317211-121317211

c.222C>T; p.S74S; 9:121302936-121302936

c.663+4C>T; p.?; 9:121312492-121312492

c.91C>T; p.P31S; 9:121302062-121302062

c.1496G>A; p.G499D; 9:121326591-121326591

c.2045C>T; p.T682M; 9:121332452-121332452

c.2068C>G; p.R690G; 9:121332475-121332475

c.303C>T; p.F101F; 9:121303017-121303017

c.303C>T; p.F101F; 9:121303017-121303017

c.1058G>A; p.G353D; 9:121318747-121318747

c.2189C>A; p.A730D; 9:121332596-121332596

c.1924C>T; p.L642L; 9:121329274-121329274

c.1588-1G>T; p.?; 9:121327307-121327307

c.700G>A; p.E234K; 9:121313970-121313970

c.757T>C; p.S253P; 9:121317089-121317089

c.390C>T; p.P130P; 9:121310722-121310722

c.557G>C; p.R186T; 9:121312382-121312382

c.1838C>T; p.A613V; 9:121328966-121328966

c.866G>T; p.G289V; 9:121317198-121317198

c.381C>T; p.H127H; 9:121310713-121310713

c.29A>T; p.K10M; 9:121302000-121302000

c.1251C>A; p.F417L; 9:121321327-121321327

c.753+1G>A; p.?; 9:121314024-121314024

c.127G>A; p.A43T; 9:121302098-121302098

c.127G>A; p.A43T; 9:121302098-121302098

c.2027C>T; p.A676V; 9:121332434-121332434

c.19G>T; p.E7*; 9:121301990-121301990

c.49C>A; p.L17M; 9:121302020-121302020

c.537C>T; p.S179S; 9:121312362-121312362

c.2012A>G; p.E671G; 9:121331434-121331434

c.855C>T; p.H285H; 9:121317187-121317187

c.2040C>T; p.I680I; 9:121332447-121332447

c.1260C>T; p.G420G; 9:121321336-121321336

c.1959G>T; p.W653C; 9:121329309-121329309

c.487G>A; p.D163N; 9:121310819-121310819

c.487G>A; p.D163N; 9:121310819-121310819

c.887-2A>T; p.?; 9:121318404-121318404

c.120G>A; p.T40T; 9:121302091-121302091

c.1076_1078delTTT; p.L359_S360>P; 9:121318765-121318767

c.466T>C; p.W156R; 9:121310798-121310798

c.308C>A; p.S103*; 9:121303022-121303022

c.2066G>A; p.R689Q; 9:121332473-121332473

c.1679G>A; p.S560N; 9:121327399-121327399

c.823C>A; p.L275M; 9:121317155-121317155

c.154C>A; p.L52M; 9:121302125-121302125

c.206G>A; p.C69Y; 9:121302920-121302920

c.1000G>C; p.E334Q; 9:121318689-121318689

c.1000G>C; p.E334Q; 9:121318689-121318689

c.2082C>A; p.T694T; 9:121332489-121332489

c.803A>G; p.N268S; 9:121317135-121317135

c.397G>A; p.V133M; 9:121310729-121310729

c.1288C>T; p.R430C; 9:121321364-121321364

c.196+2_196+4delTGA; p.?; 9:121302169-121302171

c.196+2_196+4delTGA; p.?; 9:121302169-121302171

c.680C>A; p.P227Q; 9:121313950-121313950

c.731G>A; p.R244H; 9:121314001-121314001

c.79C>A; p.L27M; 9:121302050-121302050

c.1750G>A; p.G584S; 9:121327470-121327470

c.1117G>A; p.A373T; 9:121318806-121318806

c.351+2T>G; p.?; 9:121303067-121303067

c.1424T>C; p.V475A; 9:121326519-121326519

c.1533C>T; p.S511S; 9:121326628-121326628

c.867G>A; p.G289G; 9:121317199-121317199

c.40G>A; p.E14K; 9:121302011-121302011

c.1023C>A; p.F341L; 9:121318712-121318712

c.753+3G>A; p.?; 9:121314026-121314026

c.1223C>G; p.P408R; 9:121321299-121321299