Entrez Gene

Basic Information
Gene ID	2934
Name	GSN
Synonymous	ADF\|AGEL;gelsolin;GSN;gelsolin
Definition	actin-depolymerizing factor\|brevin
Position	9q33
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
gelsolin(h) --Caspase-3(h)--> protein remnants (processing)
actin(h) + PLCgamma1(h) + gelsolin(h) <==> actin(h):PLCgamma1(h):gelsolin(h) (binding)
Caspase-4(h) + gelsolin(h) <==> Caspase-4(h):gelsolin(h) (binding)
PP2Cbeta(h) + gelsolin(h) <==> PP2Cbeta(h):gelsolin(h) (binding)
AR(h) + gelsolin(h) <==> AR(h):gelsolin(h) (binding)
GSN(h) --> gelsolin(h) (expression).
actin(h):PLCgamma1(h):gelsolin(h) <==> actin(h) + gelsolin(h) + PLCgamma1(h) (dissociation)
GSN(h) --> gelsolin-isoform1(h) (expression).
GSN(h) --> gelsolin-isoform2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
86	Phosphotyrosine; by SRC; in vitro.		Swiss-Prot 53.0
409	Phosphotyrosine; by SRC; in vitro.		Swiss-Prot 53.0
465	Phosphotyrosine (by SRC).		Swiss-Prot 53.0
603	Phosphotyrosine; by SRC; in vitro.		Swiss-Prot 53.0
651	Phosphotyrosine; by SRC; in vitro.		Swiss-Prot 53.0
465	Phosphotyrosine (Src)	10210201	Phospho.ELM 6.0