| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 9141 |
Name | PDCD5 |
Synonymous | programmed cell death 5;PDCD5;programmed cell death 5 |
Definition | TF-1 cell apoptosis-related protein 19|TF1 cell apoptosis-related gene 19|TFAR19 novel apoptosis-related|programmed cell death protein 5 |
Position | 19q13.11 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
 |
The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
 |
 |
Loss of Function mutations compare to missense mutations | Top |
 |
| The ratio of the loss-of-function mutations over missense mutations is 0.00. |
The copy number variations for various cancers | Top |
 |
The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
|
Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.27G>A; p.L9L; 19:32581288-32581288 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.165G>T; p.R55S; 19:32585010-32585010 |
lung | carcinoma; non_small_cell_carcinoma | Substitution - Missense |
c.265G>C; p.E89Q; 19:32586864-32586864 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.255G>T; p.E85D; 19:32585904-32585904 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.364G>C; p.D122H; 19:32587286-32587286 |
breast | carcinoma | Substitution - Missense |
c.254A>G; p.E85G; 19:32585903-32585903 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.254A>G; p.E85G; 19:32585903-32585903 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.254A>G; p.E85G; 19:32585903-32585903 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.254A>G; p.E85G; 19:32585903-32585903 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.169A>G; p.S57G; 19:32585818-32585818 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.88C>T; p.Q30*; 19:32582216-32582216 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Substitution - Nonsense |
c.122A>G; p.N41S; 19:32584967-32584967 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.163A>G; p.R55G; 19:32585008-32585008 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.163A>G; p.R55G; 19:32585008-32585008 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.255G>C; p.E85D; 19:32585904-32585904 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.247C>A; p.L83I; 19:32585896-32585896 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.258G>T; p.K86N; 19:32585907-32585907 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.253G>A; p.E85K; 19:32585902-32585902 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.82G>A; p.A28T; 19:32582210-32582210 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.253G>A; p.E85K; 19:32585902-32585902 |
lung; right_lower_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.213G>T; p.E71D; 19:32585862-32585862 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.255G>A; p.E85E; 19:32585904-32585904 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |