Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1634

Name

DCN

Synonymous

CSCD|DSPG2|PG40|PGII|PGS2|SLRR1B;decorin;DCN;decorin

Definition

PG-S2|bone proteoglycan II|decorin proteoglycan|dermatan sulphate proteoglycans II|proteoglycan core protein|small leucine-rich protein 1B

Position

12q21.33

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for DCN

Transcription Factors   [Top]

Regulation From TransFac database

DCN(h) --> Decorin-A(h) (expression).
DCN(h) --> Decorin(h) (expression).
DCN(h) --> Decorin-B(h) (expression).
DCN(h) --> Decorin-C(h) (expression).
DCN(h) --> Decorin-D(h) (expression).
DCN(h) --> Decorin-E(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

34O-linked (Xyl...) (glycosaminoglycan).Swiss-Prot 53.0
211N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
262N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
303N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
34O-linkedRoughley PJ. and White RJ. (1989) Biochem. J., 262, 823-827.Mann DM., Yamaguchi Y., Bourdon MA. and Ruoslahti E. (1990)J. Biol. Chem., 265, 5317-5323. Medline: 90203025;OGlycBase6.0
4O-linkedRoughley PJ. and White RJ. (1989) Biochem. J., 262, 823-827.Mann DM., Yamaguchi Y., Bourdon MA. and Ruoslahti E. (1990)J. Biol. Chem., 265, 5317-5323. Medline: 90203025;OGlycBase6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr12

Promoter: 90100437 - 90102437GoldenGate_Methylation_Cancer_Panel_I

chr12

Promoter: 90100437 - 90102437GSE27584

chr12

Promoter: 90100437 - 90102437E-GEOD-20553

chr12

Promoter: 90096990 - 90098990E-GEOD-20553

chr12

Promoter: 90095960 - 90097960E-GEOD-20553

chr12

Promoter: 90095960 - 90097960E-GEOD-20553

chr12

Promoter: 90095960 - 90097960E-GEOD-20553

chr12

Promoter: 90095960 - 90097960E-GEOD-20553


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