Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2048

Name

EPHB2

Synonymous

CAPB|DRT|EK5|EPHT3|ERK|Hek5|PCBC|Tyro5;EPH receptor B2;EPHB2;EPH receptor B2

Definition

EPH-like kinase 5|developmentally-regulated Eph-related tyrosine kinase|elk-related tyrosine kinase|eph tyrosine kinase 3|ephrin type-B receptor 2|protein-tyrosine kinase HEK5|renal carcinoma antigen NY-REN-47|tyrosine-protein kinase TYRO5|tyrosine-protei

Position

1p36.1-p35

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

EPHB2(h) --> EPHB2-isoform1(h) (expression).
EPHB2(h) --> EPHB2-isoform2(h) (expression).
EPHB2(h) --> EPHB2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
336N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
428N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
482N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
596Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
602Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
775Phosphothreonine.Swiss-Prot 53.0
780Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
930Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 22908418 - 22910418Agilent_014791

chr1

Promoter: 22908418 - 22910418GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 22908418 - 22910418GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 22908418 - 22910418GSE27584

chr1

Promoter: 22908418 - 22910418GSE27584

chr1

Promoter: 22908418 - 22910418Agilent_014791_44K

chr1

Promoter: 22908418 - 22910418PMID:17183069

chr1

Promoter: 22908418 - 22910418PMID:17183069


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