General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 5074 |
Name | PAWR |
Synonymous | PAR4|Par-4;PRKC, apoptosis, WT1, regulator;PAWR;PRKC, apoptosis, WT1, regulator |
Definition | PRKC apoptosis WT1 regulator protein|WT1-interacting protein|prostate apoptosis response 4 protein|prostate apoptosis response protein 4|prostate apoptosis response protein PAR-4|prostate apoptosis response-4|transcriptional repressor PAR4 |
Position | 12q21 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
pawr(h) + PKCzeta(r) <==> pawr(h):PKCzeta(r) (binding) | pawr(h) + PKCiota(x) <==> pawr(h):PKCiota(x) (binding) | pawr(h) + WT1(h) <==> pawr(h):WT1(h) (binding) | pawr(h) + ZIPK(h) <==> pawr(h):ZIPK(h) (binding) | D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding) | D2(h) + pawr(h) <==> D2(h):pawr(h) (binding) | pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding) | ICEN22(h) + pawr(h) <==> ICEN22(h):pawr(h) (binding) | PAWR(h) --> pawr(h) (expression). | D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding) | pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding) | pawr(h) --> DIABLO(h) (transactivation) | PAWR(h) --> pawr(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
163 | Phosphothreonine (by PKA) (Bysimilarity). | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr12 |
Promoter: 78608421 - 78610421 | Agilent_014791 |
chr12 |
Promoter: 78608421 - 78610421 | GSE27584 |
chr12 |
Promoter: 78608421 - 78610421 | Agilent_014791_44K |