Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5074

Name

PAWR

Synonymous

PAR4|Par-4;PRKC, apoptosis, WT1, regulator;PAWR;PRKC, apoptosis, WT1, regulator

Definition

PRKC apoptosis WT1 regulator protein|WT1-interacting protein|prostate apoptosis response 4 protein|prostate apoptosis response protein 4|prostate apoptosis response protein PAR-4|prostate apoptosis response-4|transcriptional repressor PAR4

Position

12q21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

pawr(h) + PKCzeta(r) <==> pawr(h):PKCzeta(r) (binding)
pawr(h) + PKCiota(x) <==> pawr(h):PKCiota(x) (binding)
pawr(h) + WT1(h) <==> pawr(h):WT1(h) (binding)
pawr(h) + ZIPK(h) <==> pawr(h):ZIPK(h) (binding)
D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding)
D2(h) + pawr(h) <==> D2(h):pawr(h) (binding)
pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding)
ICEN22(h) + pawr(h) <==> ICEN22(h):pawr(h) (binding)
PAWR(h) --> pawr(h) (expression).
D2-isoform1(h) + pawr(h) <==> D2-isoform1(h):pawr(h) (binding)
pawr(h) + E2F-1(h) <==> pawr(h):E2F-1(h) (binding)
pawr(h) --> DIABLO(h) (transactivation)
PAWR(h) --> pawr(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

163Phosphothreonine (by PKA) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr12

Promoter: 78608421 - 78610421Agilent_014791

chr12

Promoter: 78608421 - 78610421GSE27584

chr12

Promoter: 78608421 - 78610421Agilent_014791_44K


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