Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51720

Name

UIMC1

Synonymous

RAP80|X2HRIP110;ubiquitin interaction motif containing 1;UIMC1;ubiquitin interaction motif containing 1

Definition

BRCA1-A complex subunit RAP80|receptor associated protein 80|receptor-associated protein 80|retinoid X receptor-interacting protein 110|retinoid x receptor interacting protein|ubiquitin interaction motif-containing protein 1

Position

5q35.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for UIMC1

Transcription Factors   [Top]

Regulation From TransFac database

brca1(m.s.) + RAP80(h) <==> brca1(m.s.):RAP80(h) (binding)
brca1(h) + RAP80(h) <==> brca1(h):RAP80(h) (binding)
CCDC98(h) + RAP80(h) <==> CCDC98(h):RAP80(h) (binding)
CtIP(h) + RAP80(h) <==> CtIP(h):RAP80(h) (binding)
CCDC98(m.s.) + RAP80(h) <==> CCDC98(m.s.):RAP80(h) (binding)
RAP80(h) + BARD1(h) <==> RAP80(h):BARD1(h) (binding)
RAP80(h) + ATP --> RAP80(h){p} + ADP (phosphorylation)
RAP80(h) + brca1(h) <==> RAP80(h):brca1(h) (binding)
BRCC36(h) + RAP80(h) <==> BRCC36(h):RAP80(h) (binding)
UIMC1(h) --> RAP80(h) (expression).
UIMC1(h) --> RAP80-isoform1(h) (expression).
UIMC1(h) --> RAP80-isoform2(h) (expression).
UIMC1(h) --> RAP80-isoform3(h) (expression).
UIMC1(h) --> RAP80-isoform4(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

44Phosphoserine.Swiss-Prot 53.0
46Phosphoserine.Swiss-Prot 53.0
597Phosphoserine.Swiss-Prot 53.0
653Phosphoserine.Swiss-Prot 53.0
677Phosphoserine.Swiss-Prot 53.0
597Phosphoserine15302935Phospho.ELM 6.0
653Phosphoserine15302935Phospho.ELM 6.0
677Phosphoserine15302935Phospho.ELM 6.0
44Phosphoserine17081983Phospho.ELM 6.0
46Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 176365549 - 176367549GSE27584

chr5

Promoter: 176365549 - 176367549Agilent_014791_44K


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