Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6282

Name

S100A11

Synonymous

HEL-S-43|MLN70|S100C;S100 calcium binding protein A11;S100A11;S100 calcium binding protein A11

Definition

MLN 70|S100 calcium-binding protein A11 (calgizzarin)|calgizzarin|epididymis secretory protein Li 43|metastatic lymph node gene 70 protein|protein S100-A11|protein S100-C

Position

1q21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

s100a11(h) --> AKT(h){p} (increase of phosphorylation)
s100a11(h) --> Bcl-2(h) (increase of abundance)
s100a11(h) --/ p21Cip1(h) (decrease of abundance)
s100a11(h) --/ p27Kip1(h) (decrease of abundance)
s100a11(h) --> s100a11(h) (expression).
s100a11(h) + ATP --PKCalpha(rb)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCdelta(m)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCepsilon(m.s.)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) + ATP --PKCeta(m)--> s100a11(h){pT10} + ADP (phosphorylation)
s100a11(h) --> s100a11(h) (expression).
EGF(h) --> s100a11(h) (increase of abundance)
Ca --> s100a11(h) (increase of abundance)
GROalpha(h) --> s100a11(h) (increase of abundance)
TGFalpha(h) --> s100a11(h) (increase of abundance)

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

6Phosphoserine.Swiss-Prot 53.0
94Phosphoserine14623863Phospho.ELM 6.0
10Phosphothreonine10851017;14623863Phospho.ELM 6.0
6Phosphoserine15302935;17081983Phospho.ELM 6.0
71Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 150275635 - 150277635GSE27584

chr1

Promoter: 150275635 - 150277635E-GEOD-20553


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