| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8312 |
Name | AXIN1 |
Synonymous | AXIN|PPP1R49;axin 1;AXIN1;axin 1 |
Definition | axin-1|axis inhibition protein 1|axis inhibitor 1|fused, mouse, homolog of|protein phosphatase 1, regulatory subunit 49 |
Position | 16p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
apc(h) + axin(h) + beta-catenin(h) <==> apc(h):axin(h):beta-catenin(h) (binding) | apc(h) + axin(h) <==> apc(h):axin(h) (binding) | axin(h) + GSK3beta(r) <==> axin(h):GSK3beta(r) (binding) | axin(h) + ATP --GSK3beta(h)--> axin(h){p} + ADP (phosphorylation) | beta-catenin(h) + axin(h) <==> axin(h):beta-catenin(h) (binding) | apc(h) + axin(h) + beta-catenin(h) + GSK3beta(h) <==> apc(h):axin(h):beta-catenin(h):GSK3beta(h) (binding) | axin(h) + LRP6(h){pS1490} <==> axin(h):LRP6(h){pS1490} (binding) | axin(h) + GSK3beta(h) + PR65(h) + PP2ACalpha(h) + beta-catenin(h) <==> axin(h):beta-catenin(h):GSK3beta(h):PP2ACalpha(h):PR65(h) (binding) | axin(h) + CKI-epsilon(h) <==> axin(h):CKI-epsilon(h) (binding) | axin(h) + GSK3beta(h) <==> axin(h):GSK3beta(h) (binding) | axin(h) + Daxx(h) <==> axin(h):Daxx(h) (binding) | HSKM-B(h) + axin(h) <==> HSKM-B(h):axin(h) (binding) | axin(h) + CRMP1(h) <==> axin(h):CRMP1(h) (binding) | axin(h) + EEF1A(h) <==> axin(h):EEF1A(h) (binding) | axin(h) + PP32(h) <==> axin(h):PP32(h) (binding) | AXIN1(h) --> axin(h) (expression). | axin(h) --> Smad3(mv){p} (increase of phosphorylation) | AXIN1(h) --> axin(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for AXIN1 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr16 |
Promoter: 341965 - 343965 | Agilent_014791 |
chr16 |
Promoter: 341965 - 343965 | GoldenGate_Methylation_Cancer_Panel_I |
chr16 |
Promoter: 341965 - 343965 | GoldenGate_Methylation_Cancer_Panel_I |
chr16 |
Promoter: 341965 - 343965 | GSE27584 |
chr16 |
Promoter: 341965 - 343965 | GSE27584 |
chr16 |
Promoter: 341965 - 343965 | Agilent_014791_44K |
chr16 |
Promoter: 341965 - 343965 | Agilent_014791 |