Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8870

Name

IER3

Synonymous

DIF-2|DIF2|GLY96|IEX-1|IEX-1L|IEX1|PRG1;immediate early response 3;IER3;immediate early response 3

Definition

PACAP-responsive gene 1 protein|anti-death protein|differentiation-dependent gene 2 protein|expressed in pancreatic carcinoma|gly96, mouse, homolog of|immediate early protein GLY96|immediate early response 3 protein|immediately early gene X-1|protein DIF-

Position

6p21.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Mcl-1(h) + IEX1(h) <==> Mcl-1(h):IEX1(h) (binding)
IEX1(h) + ATP --ERK2(r)--> IEX1(h){pT18} + ADP (phosphorylation)
ERK1(h){p} + IEX1(h) <==> ERK1(h){p}:IEX1(h) (binding)
IEX1(h) + ERK2(h){p} <==> IEX1(h):ERK2(h){p} (binding)
IEX1(h) --> ERK1(m.s.){p} (increase of phosphorylation)
CAML(h) + IEX1(h) <==> CAML(h):IEX1(h) (binding)
IEX1(h) + Apo2L(h) <==> IEX1(h):Apo2L(h) (binding)
IEX1(h) + protein G3(h) <==> IEX1(h):protein G3(h) (binding)
IEX1(h) + zyxin(h) <==> IEX1(h):zyxin(h) (binding)
IEX1(h) + ZnT-9(h) <==> IEX1(h):ZnT-9(h) (binding)
IEX1(h) + peroxisomal bifunctional enzyme(h) <==> IEX1(h):peroxisomal bifunctional enzyme(h) (binding)
IEX1(h) + beta5-integrin(h) <==> IEX1(h):beta5-integrin(h) (binding)
IEX1(h) + Alpha-SGT(h) <==> IEX1(h):Alpha-SGT(h) (binding)
IEX1(h) + atp1b1(h) <==> IEX1(h):atp1b1(h) (binding)
IEX1(h) + pf4v1(h) <==> IEX1(h):pf4v1(h) (binding)
IER3(h) --> IEX1(h) (expression).
Mcl-1L(h) + IEX1(h) <==> Mcl-1L(h):IEX1(h) (binding)
Mcl-1(h) + IEX1(h) <==> Mcl-1(h):IEX1(h) (binding)
IER3(h) --> IEX1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

133N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
18Phosphothreonine (MAPK6)12356731Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for IER3



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