Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

11228

Name

RASSF8

Synonym

C12orf2|HOJ1;Ras association (RalGDS/AF-6) domain family (N-terminal) member 8;RASSF8;Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

Definition

carcinoma-associated protein HOJ-1|ras association domain-containing protein 8

Position

12p12.3

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

reviewed

RASSF8 as a tumor suppressor gene that is essential for maintaining AJs function in epithelial cells and have a role in epithelial cell migration.

potential

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.

potential

Identification of RASSF8 as a candidate lung tumor suppressor gene.
More detail of all 2 literatures about RASSF8

External Links

Links to Entrez Gene

11228

Links to all GeneRIF Items

11228

Links to iHOP

11228

Sequence Information

Nucleotide Sequence

>11228 : length: 1260
atggaacttaaagtatgggtggatggagttcagaggattgtttgtggagtcactgaagtc
acaacttgccaggaggttgtcatagccttagctcaagcaataggtcgaactggaaggtac
acccttatagagaaatggagagatactgaaagacacttagcacctcatgaaaatcctatc
atatccttaaacaaatgggggcagtatgctagtgatgtgcagctcattctacgacgaact
gggccgtctctcagtgagcgacccacttcagacagtgtggctcgaattcctgaaagaact
ttatacaggcagagtctgccccccttagctaaactgaggcctcagattgacaaatcaatc
aaaaggagggaaccgaaaaggaaatcactgacatttacaggaggtgccaaaggattaatg
gacatttttggaaaaggtaaagaaactgagtttaagcaaaaggtgctgaataactgcaaa
acaacagcagatgagttgaagaagctaatccgtctgcagacagagaagcttcaatccatt
gagaaacagctggaatctaatgaaatagaaataagattttgggagcaaaagtataattcc
aaccttgaagaggaaattgtccgtctagagcaaaagatcaaaagaaacgatgtagaaatt
gaggaggaagaattctgggaaaatgaattacagattgaacaggaaaatgaaaaacagctg
aaggatcaacttcaagaaataagacagaaaataacagaatgtgaaaacaaattaaaggac
tatttggcacagatccggactatggaaagtggtcttgaagcagaaaaattgcaacgggaa
gttcaagaggcacaggtcaatgaggaagaggttaaaggaaagatcggtaaggtcaaaggg
gagattgacattcaaggccagcagagtctgaggttggaaaatggcatcaaagctgtggaa
agatctcttggacaagccaccaaacgcttacaggacaaagaacaggaactggagcagttg
actaaggagttgcggcaagtcaatctccagcagttcatccagcagacagggacaaaagtt
accgttttgccagcggagcccattgaaatagaggcctcacatgcagacattgaaagggag
gcaccattccagtctgggtccctgaagcgacctggttcatctcggcagctccccagtaat
ctccgcattctgcagaatcctatctcatctggttttaatcctgaaggcatatatgtatga

Protein Sequence

>11228 : length: 419
MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI
ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI
KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI
EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL
KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG
EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV
TVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV



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