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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 11228 |
Name | RASSF8 |
Synonym | C12orf2|HOJ1;Ras association (RalGDS/AF-6) domain family (N-terminal) member 8;RASSF8;Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
Definition | carcinoma-associated protein HOJ-1|ras association domain-containing protein 8 |
Position | 12p12.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | RASSF8 as a tumor suppressor gene that is essential for maintaining AJs function in epithelial cells and have a role in epithelial cell migration. |
potential | The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways. |
potential | Identification of RASSF8 as a candidate lung tumor suppressor gene. |
| More detail of all 2 literatures about RASSF8 | |
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External Links |
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Links to Entrez Gene | 11228 |
Links to all GeneRIF Items | 11228 |
Links to iHOP | 11228 |
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Sequence Information |
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Nucleotide Sequence |
>11228 : length: 1260 atggaacttaaagtatgggtggatggagttcagaggattgtttgtggagtcactgaagtc acaacttgccaggaggttgtcatagccttagctcaagcaataggtcgaactggaaggtac acccttatagagaaatggagagatactgaaagacacttagcacctcatgaaaatcctatc atatccttaaacaaatgggggcagtatgctagtgatgtgcagctcattctacgacgaact gggccgtctctcagtgagcgacccacttcagacagtgtggctcgaattcctgaaagaact ttatacaggcagagtctgccccccttagctaaactgaggcctcagattgacaaatcaatc aaaaggagggaaccgaaaaggaaatcactgacatttacaggaggtgccaaaggattaatg gacatttttggaaaaggtaaagaaactgagtttaagcaaaaggtgctgaataactgcaaa acaacagcagatgagttgaagaagctaatccgtctgcagacagagaagcttcaatccatt gagaaacagctggaatctaatgaaatagaaataagattttgggagcaaaagtataattcc aaccttgaagaggaaattgtccgtctagagcaaaagatcaaaagaaacgatgtagaaatt gaggaggaagaattctgggaaaatgaattacagattgaacaggaaaatgaaaaacagctg aaggatcaacttcaagaaataagacagaaaataacagaatgtgaaaacaaattaaaggac tatttggcacagatccggactatggaaagtggtcttgaagcagaaaaattgcaacgggaa gttcaagaggcacaggtcaatgaggaagaggttaaaggaaagatcggtaaggtcaaaggg gagattgacattcaaggccagcagagtctgaggttggaaaatggcatcaaagctgtggaa agatctcttggacaagccaccaaacgcttacaggacaaagaacaggaactggagcagttg actaaggagttgcggcaagtcaatctccagcagttcatccagcagacagggacaaaagtt accgttttgccagcggagcccattgaaatagaggcctcacatgcagacattgaaagggag gcaccattccagtctgggtccctgaagcgacctggttcatctcggcagctccccagtaat ctccgcattctgcagaatcctatctcatctggttttaatcctgaaggcatatatgtatga |
Protein Sequence |
>11228 : length: 419 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPI ISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPPLAKLRPQIDKSI KRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTEKLQSI EKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFWENELQIEQENEKQL KDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKG EIDIQGQQSLRLENGIKAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKV TVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSRQLPSNLRILQNPISSGFNPEGIYV |