Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1959

Name

EGR2

Synonym

AT591|CMT1D|CMT4E|KROX20;early growth response 2;EGR2;early growth response 2

Definition

E3 SUMO-protein ligase EGR2|EGR-2|KROX-20, Drosophila, homolog (early growth response-2)|Krox-20 homolog, Drosophila|early growth response protein 2|zinc finger protein Krox-20

Position

10q21.1

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

overexpression of miR-150 in gastric cancer could promote proliferation and growth of cancer cells at least partially through directly targeting the tumor-suppressor EGR2.
More detail of all 1 literatures about EGR2

Pathways and Diseases

Pathway

Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039

Pathway

IL4-mediated signaling events;PID Curated;200018

Disease

Charcot-Marie-Tooth disease, type 1D;OMIM

Disease

Polyneuropathy;FunDO

Disease

peripheral demyelinating neuropathies;GAD

Disease

Charcot-Marie-Tooth disease;FunDO

Disease

Neuropathy, congenital hypomyelinating, 1;OMIM

Disease

Dejerine-Sottas neuropathy;OMIM

Disease

CARDIOVASCULAR;GAD

Disease

Charcot-Marie-Tooth type 1 disease;GAD

Disease

neuropathy;GAD

Disease

NEUROLOGICAL;GAD

External Links

Links to Entrez Gene

1959

Links to all GeneRIF Items

1959

Links to iHOP

1959

Sequence Information

Nucleotide Sequence

>1959 : length: 1431
atgatgaccgccaaggccgtagacaaaatcccagtaactctcagtggttttgtgcaccag
ctgtctgacaacatctacccggtggaggacctcgccgccacgtcggtgaccatctttccc
aatgccgaactgggaggcccctttgaccagatgaacggagtggccggagatggcatgatc
aacattgacatgactggagagaagaggtcgttggatctcccatatcccagcagctttgct
cccgtctctgcacctagaaaccagaccttcacttacatgggcaagttctccattgaccct
cagtaccctggtgccagctgctacccagaaggcataatcaatattgtgagtgcaggcatc
ttgcaaggggtcacttccccagcttcaaccacagcctcatccagcgtcacctctgcctcc
cccaacccactggccacaggacccctgggtgtgtgcaccatgtcccagacccagcctgac
ctggaccacctgtactctccgccaccgcctcctcctccttattctggctgtgcaggagac
ctctaccaggacccttctgcgttcctgtcagcagccaccacctccacctcttcctctctg
gcctacccaccacctccttcctatccatcccccaagccagccacggacccaggtctcttc
ccaatgatcccagactatcctggattctttccatctcagtgccagagagacctacatggt
acagctggcccagaccgtaagccctttccctgcccactggacaccctgcgggtgccccct
ccactcactccactctctacaatccgtaactttaccctggggggccccagtgctggggtg
accggaccaggggccagtggaggcagcgagggaccccggctgcctggtagcagctcagca
gcagcagcagccgccgccgccgccgcctataacccacaccacctgccactgcggcccatt
ctgaggcctcgcaagtaccccaacagacccagcaagacgccggtgcacgagaggccctac
ccgtgcccagcagaaggctgcgaccggcggttctcccgctctgacgagctgacacggcac
atccgaatccacactgggcataagcccttccagtgtcggatctgcatgcgcaacttcagc
cgcagtgaccacctcaccacccatatccgcacccacaccggtgagaagcccttcgcctgt
gactactgtggccgaaagtttgcccggagtgatgagaggaagcgccacaccaagatccac
ctgagacagaaagagcggaaaagcagtgccccctctgcatcggtgccagccccctctaca
gcctcctgctctgggggcgtgcagcctgggggtaccctgtgcagcagtaacagcagcagt
cttggcggagggccgctcgccccttgctcctctcggacccggacaccttga

Protein Sequence

>1959 : length: 476
MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI
NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI
LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD
LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG
TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA
AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH
IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH
LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP



Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas