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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 1959 |
Name | EGR2 |
Synonym | AT591|CMT1D|CMT4E|KROX20;early growth response 2;EGR2;early growth response 2 |
Definition | E3 SUMO-protein ligase EGR2|EGR-2|KROX-20, Drosophila, homolog (early growth response-2)|Krox-20 homolog, Drosophila|early growth response protein 2|zinc finger protein Krox-20 |
Position | 10q21.1 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | overexpression of miR-150 in gastric cancer could promote proliferation and growth of cancer cells at least partially through directly targeting the tumor-suppressor EGR2. |
| More detail of all 1 literatures about EGR2 | |
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Pathways and Diseases |
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Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Disease | Charcot-Marie-Tooth disease, type 1D;OMIM |
Disease | Polyneuropathy;FunDO |
Disease | peripheral demyelinating neuropathies;GAD |
Disease | Charcot-Marie-Tooth disease;FunDO |
Disease | Neuropathy, congenital hypomyelinating, 1;OMIM |
Disease | Dejerine-Sottas neuropathy;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | Charcot-Marie-Tooth type 1 disease;GAD |
Disease | neuropathy;GAD |
Disease | NEUROLOGICAL;GAD |
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External Links |
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Links to Entrez Gene | 1959 |
Links to all GeneRIF Items | 1959 |
Links to iHOP | 1959 |
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Sequence Information |
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Nucleotide Sequence |
>1959 : length: 1431 atgatgaccgccaaggccgtagacaaaatcccagtaactctcagtggttttgtgcaccag ctgtctgacaacatctacccggtggaggacctcgccgccacgtcggtgaccatctttccc aatgccgaactgggaggcccctttgaccagatgaacggagtggccggagatggcatgatc aacattgacatgactggagagaagaggtcgttggatctcccatatcccagcagctttgct cccgtctctgcacctagaaaccagaccttcacttacatgggcaagttctccattgaccct cagtaccctggtgccagctgctacccagaaggcataatcaatattgtgagtgcaggcatc ttgcaaggggtcacttccccagcttcaaccacagcctcatccagcgtcacctctgcctcc cccaacccactggccacaggacccctgggtgtgtgcaccatgtcccagacccagcctgac ctggaccacctgtactctccgccaccgcctcctcctccttattctggctgtgcaggagac ctctaccaggacccttctgcgttcctgtcagcagccaccacctccacctcttcctctctg gcctacccaccacctccttcctatccatcccccaagccagccacggacccaggtctcttc ccaatgatcccagactatcctggattctttccatctcagtgccagagagacctacatggt acagctggcccagaccgtaagccctttccctgcccactggacaccctgcgggtgccccct ccactcactccactctctacaatccgtaactttaccctggggggccccagtgctggggtg accggaccaggggccagtggaggcagcgagggaccccggctgcctggtagcagctcagca gcagcagcagccgccgccgccgccgcctataacccacaccacctgccactgcggcccatt ctgaggcctcgcaagtaccccaacagacccagcaagacgccggtgcacgagaggccctac ccgtgcccagcagaaggctgcgaccggcggttctcccgctctgacgagctgacacggcac atccgaatccacactgggcataagcccttccagtgtcggatctgcatgcgcaacttcagc cgcagtgaccacctcaccacccatatccgcacccacaccggtgagaagcccttcgcctgt gactactgtggccgaaagtttgcccggagtgatgagaggaagcgccacaccaagatccac ctgagacagaaagagcggaaaagcagtgccccctctgcatcggtgccagccccctctaca gcctcctgctctgggggcgtgcagcctgggggtaccctgtgcagcagtaacagcagcagt cttggcggagggccgctcgccccttgctcctctcggacccggacaccttga |
Protein Sequence |
>1959 : length: 476 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP |