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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 23095 |
Name | KIF1B |
Synonym | CMT2|CMT2A|CMT2A1|HMSNII|KLP|NBLST1;kinesin family member 1B;KIF1B;kinesin family member 1B |
Definition | kinesin superfamily protein KIF1B|kinesin-like protein KIF1B |
Position | 1p36.2 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | "KIF1Bbeta may act as a haploinsufficient tumor suppressor, and its allelic loss may be involved in the pathogenesis of neuroblastoma and other cancers." |
potential | The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. |
| More detail of all 2 literatures about KIF1B | |
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External Links |
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Links to Entrez Gene | 23095 |
Links to all GeneRIF Items | 23095 |
Links to iHOP | 23095 |
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Sequence Information |
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Nucleotide Sequence |
>23095 : length: 5313 atgtcgggagcctcagtgaaggtggctgtccgggtaaggcccttcaattctcgagagacc agcaaggaatccaaatgcatcattcagatgcaaggcaactcgaccagtattattaaccca aagaatccaaaggaagctccaaagtccttcagcttcgactattcctactggtctcatacc tcacccgaagatccctgttttgcatctcaaaaccgtgtgtacaatgacattggcaaggaa atgctcttacacgcctttgagggatataatgtctgtatttttgcctatgggcagactggt gctggaaaatcttatacaatgatgggtaaacaagaagaaagccaggctggcatcattcca cagttatgtgaagaactttttgagaaaatcaatgacaactgtaatgaagaaatgtcttac tctgtagaggtgagctacatggaaatttactgtgaaagagtacgagatttgctgaatcca aaaaacaagggtaatttgcgtgtgcgtgaacacccacttcttggaccctatgtggaggat ctgtccaagttggcagttacttcctacacagacattgctgacctcatggatgctgggaac aaagccaggacagtggcagctacaaacatgaatgaaacaagtagccgttcccacgctgtg tttacgattgttttcacccagaagaaacacgataatgagaccaacctttccactgagaag gtcagtaaaatcagcttggtggatctagcaggaagtgaacgagctgattcaactggtgcc aaagggactcgattaaaggaaggagcaaatattaataagtctcttacaactttgggcaaa gtcatttcagccttggccgaggtgagtaaaaagaagaagaaaacagattttattccctac agggattctgtacttacttggctccttcgagaaaatttaggtggcaattctcggactgca atggttgctgctctgagccccgcggatatcaactacgatgagactttgagcactctgaga tatgcagatcgtgcaaaacaaattaaatgcaatgctgttatcaatgaggaccccaatgcc aaactggttcgtgaattaaaggaggaggtgacacggctgaaggaccttcttcgtgctcag ggcctgggagatattattgatacatccatggggtccctcacttcatccccatcttcctgc tcactcagtagtcaggtgggcttgacgtctgtgaccagtattcaagagaggatcatgtct acacctggaggagaggaagctattgaacgtttaaaggaatcagagaagatcattgctgag ttgaatgaaacttgggaagagaagcttcgtaaaacagaggccatcagaatggagagagag gctttgttggctgagatgggagttgccattcgggaagatggaggaaccctaggggttttc tcacctaaaaagaccccacatcttgttaacctcaatgaagacccactaatgtctgagtgc ctactttattacatcaaagatggaattacaagggttggccaagcagatgctgagcggcgc caggacatagtgctgagcggggctcacattaaagaagagcattgtatcttccggagtgag agaagcaacagcggggaagttatcgtgaccttagagccctgtgagcgctcagaaacctac gtaaatggcaagagggtgtcccagcctgttcagctgcgctcaggaaaccgtatcatcatg ggtaaaaaccatgttttccgctttaaccacccggaacaagcacgagctgagcgagagaag actccttctgctgagaccccctctgagcctgtggactggacatttgcccagagggagctt ctggaaaaacaaggaattgatatgaaacaagagatggagaaaaggctacaggaaatggag atcttatacaaaaaggagaaggaagaagcagatcttcttttggagcagcagagactggac tatgagagtaaattgcaggccttgcagaagcaggttgaaacccgatctctggctgcagaa acaactgaagaggaggaagaagaggaagaagttccttggacacagcatgaatttgagttg gcccaatgggccttccggaaatggaagtctcatcagtttacttcattacgggacttactc tggggcaatgccgtgtacctaaaggaggccaatgccatcagtgtggaactgaaaaagaag gtgcagtttcagtttgttctgctgactgacacactgtactcccctttgcctcctgaatta cttcccactgagatggaaaaaactcatgaggacaggcctttccctcgcacagtggtagca gtagaagtccaggatttgaagaatggagcaacacactattggtctttggagaaactcaag cagaggctggatttgatgcgagagatgtatgatagggcaggggagatggcctccagtgcc caagacgaaagcgaaaccactgtgactggcagcgatcccttctatgatcggttccactgg ttcaaacttgtggggagctcccccattttccacggctgtgtgaacgagcgccttgccgac cgcacaccctcccccactttttccacggccgattccgacatcactgagctggctgacgag cagcaagatgagatggaggattttgatgatgaggcattcgtggatgacgccggctctgac gcagggacggaggagggatcagatctcttcagtgacgggcatgacccgttttacgaccga tccccttggttcattttagtgggaagggcatttgtttacctgagcaatctgctgtatccc gtgcccctgatccacagggtggccatcgtcagtgagaaaggtgaagtgcggggatttctg cgtgtggctgtacaggccatcgcagcggatgaagaagctcctgattatggctctggaatt cgacagtcaggaacagctaaaatatcttttgataatgaatactttaatcagagtgacttt tcgtctgttgcaatgactcgttctggtctgtccttggaggagttgaggattgtggaagga cagggtcagagttctgaggtcatcactcctccagaagaaatcagtcgaattaatgacttg gatttgaagtcaagcactttgctggatggtaagatggtaatggaagggttttctgaagag attggcaaccacctgaaactgggcagtgccttcactttccgagtaacagtgttgcaggcc agtggaatcctcccagagtatgcagatatcttctgtcagttcaactttttgcatcgccat gatgaagcattctccacggagcccctcaaaaacaatggcagaggaagtcccctggccttt tatcatgtgcagaatattgcagtggagatcactgaatcatttgtggattacatcaaaacc aagcctattgtatttgaagtctttgggcattatcagcagcacccacttcatctgcaagga caggagcttaacagtccgcctcagccgtgccgccgattcttccctccacccatgccactg tccaagccagttccagccaccaagttaaacacgatgagcaaaaccagccttggccagagc atgagcaagtatgacctcctggtttggtttgagatcagtgaactggagcctacaggagag tatatcccagctgtggttgaccacacagcaggcttgccttgccaggggacatttttgctt catcagggcatccagcgaaggatcacagtgaccattatccatgagaaggggagcgagctc cattggaaagatgttcgtgaactggtggtaggtcgtattcggaataagcctgaggtggat gaagctgcagttgatgccatcctctccctaaatattatttctgccaagtacctgaagtct tcccacaactctagcaggaccttctaccgctttgaggctgtgtgggatagctctctgcat aactcccttcttctgaaccgagtgacaccctatggagaaaagatctacatgaccttgtcg gcctacctagagctggatcattgcatccagccggctgtcatcaccaaggatgtgtgcatg gtcttctactcccgagatgccaagatctcaccaccacgctctctgcgtagcctctttggc agcggctactcaaagtcaccagattcgaatcgagtcactggcatttacgaactcagctta tgcaaaatgtcagacacaggtagtccaggtatgcagagaaggagaagaaaaatcttagat acgtcagtggcatatgtgcggggagaagagaacttagcaggctggcggccccgtggagac agcctcatccttgagcaccagtgggagctggagaagctggagctcctacatgaggtggaa aaaacccgccactttttgctgctgcgtgagagacttggtgacagcatccccaaatccctg agcgactcgttatcccccagcctcagcagtgggaccctcagcacctccaccagtatctcc tctcagatctcaaccactacctttgaaagcgccatcacacctagcgagagcagtggctat gattcaggagacatcgaaagcctggtggaccgagagaaagagctggctaccaagtgcctg caacttctcacccacactttcaacagagaattcagccaggtgcacggcagcgtcagtgac tgtaagttgtctgatatctctccaattggacgggatccctctgagtccagtttcagcagt gccaccctcactccctcctccacctgtccctctctggtagactctaggagcaactctctg gatcagaagaccccagaagccaattcccgggcctctagtccctgcccagaatttgaacag tttcagattgtcccagctgtggaaacaccatatttggcccgagcaggaaaaaacgaattt ctcaatcttgttccagatattgaagaaattagaccaagctcagtggtctctaagaaagga taccttcatttcaaggagcctctttacagtaactgggctaaacattttgttgtcgtccgt cggccttatgtcttcatctataacagtgacaaagaccctgtggagcgtggaatcattaac ctgtccacagcacaggtggagtacagtgaggaccagcaggccatggtgaagacaccaaac acctttgctgtctgcacaaagcaccgtggggtccttttgcaggccctcaatgacaaagac atgaacgactggttgtatgccttcaacccacttctagctggcacaatacggtcaaagctt tcccgcagatgcccgagccagtcgaaatactaa |
Protein Sequence |
>23095 : length: 1770 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIP QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED LSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEK VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPY RDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA KLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSIQERIMS TPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVF SPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSE RSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREK TPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLD YESKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLL WGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVVA VEVQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESETTVTGSDPFYDRFHW FKLVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSD AGTEEGSDLFSDGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFL RVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEG QGQSSEVITPPEEISRINDLDLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQA SGILPEYADIFCQFNFLHRHDEAFSTEPLKNNGRGSPLAFYHVQNIAVEITESFVDYIKT KPIVFEVFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQS MSKYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSEL HWKDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYRFEAVWDSSLH NSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSLFG SGYSKSPDSNRVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGD SLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSSGTLSTSTSIS SQISTTTFESAITPSESSGYDSGDIESLVDREKELATKCLQLLTHTFNREFSQVHGSVSD CKLSDISPIGRDPSESSFSSATLTPSSTCPSLVDSRSNSLDQKTPEANSRASSPCPEFEQ FQIVPAVETPYLARAGKNEFLNLVPDIEEIRPSSVVSKKGYLHFKEPLYSNWAKHFVVVR RPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMVKTPNTFAVCTKHRGVLLQALNDKD MNDWLYAFNPLLAGTIRSKLSRRCPSQSKY |