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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 23410 |
Name | SIRT3 |
Synonym | SIR2L3;sirtuin 3;SIRT3;sirtuin 3 |
Definition | NAD-dependent deacetylase sirtuin-3, mitochondrial|SIR2-like protein 3|mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase|silent mating type information regulation 2, S.cerevisiae, homolog 3|sir2-like 3|sirtuin type 3 |
Position | 11p15.5 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
Evidence Status | Description |
reviewed | "These results identify SIRT3 as a genomically expressed, mitochondria-localized tumor suppressor." |
potential | "These results identify SIRT3 as a genomically expressed, mitochondria-localized tumor suppressor." |
| More detail of all 1 literatures about SIRT3 | |
Pathways and Diseases | |
Pathway | Signaling events mediated by HDAC Class III;PID Curated;200020 |
Disease | longevity;GAD |
Disease | AGING;GAD |
External Links | |
Links to Entrez Gene | 23410 |
Links to all GeneRIF Items | 23410 |
Links to iHOP | 23410 |
Sequence Information | |
Nucleotide Sequence | >23410 : length: 774 atggtgggggccggcatcagcacacccagtggcattccagacttcagatcgccggggagt ggcctgtacagcaacctccagcagtacgatctcccgtaccccgaggccatttttgaactc ccattcttctttcacaaccccaagccctttttcactttggccaaggagctgtaccctgga aactacaagcccaacgtcactcactactttctccggctgcttcatgacaaggggctgctt ctgcggctctacacgcagaacatcgatgggcttgagagagtgtcgggcatccctgcctca aagctggttgaagctcatggaacctttgcctctgccacctgcacagtctgccaaagaccc ttcccaggggaggacattcgggctgacgtgatggcagacagggttccccgctgcccggtc tgcaccggcgttgtgaagcccgacattgtgttctttggggagccgctgccccagaggttc ttgctgcatgtggttgatttccccatggcagatctgctgctcatccttgggacctccctg gaggtggagccttttgccagcttgaccgaggccgtgcggagctcagttccccgactgctc atcaaccgggacttggtggggcccttggcttggcatcctcgcagcagggacgtggcccag ctgggggacgtggttcacggcgtggaaagcctagtggagcttctgggctggacagaagag atgcgggaccttgtgcagcgggaaactgggaagcttgatggaccagacaaatag |
Protein Sequence | >23410 : length: 257 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRP FPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSL EVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEE MRDLVQRETGKLDGPDK |