Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

2619

Name

GAS1

Synonym

-;growth arrest-specific 1;GAS1;growth arrest-specific 1

Definition

GAS-1|Growth arrest-specific gene-1|growth arrest-specific protein 1

Position

9q21.3-q22

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

"Gas1 has all the expected properties of a melanoma tumor suppressor: suppression of metastasis in a spontaneous metastasis assay, promotion of apoptosis following dissemination of cells to secondary sites, and down-regulation in human melanoma metastasis."
More detail of all 1 literatures about GAS1

Pathways and Diseases

Pathway

Signaling events mediated by the Hedgehog family;PID Curated;200144

Pathway

FOXM1 transcription factor network;PID Curated;200120

Pathway

Hedgehog signaling pathway;KEGG PATHWAY;hsa04340

Disease

Hereditary disease;FunDO

Disease

Embryoma;FunDO

Disease

CANCER;GAD

Disease

proximal chromosome 9p to q and distal chromosome 9q;GAD

External Links

Links to Entrez Gene

2619

Links to all GeneRIF Items

2619

Links to iHOP

2619

Sequence Information

Nucleotide Sequence

>2619 : length: 1038
atggtggccgcgctgctgggcggcggcggcgaggcccgcggggggacagtgccgggcgcc
tggctgtgcctgatggcgctgctgcagctgctgggctcggcgccgcggggatcggggctg
gcgcacggccgccgcctcatctgctggcaggcgctgctgcagtgccagggggagccggag
tgcagctacgcctacaaccagtacgccgaggcgtgcgcgccggtgctggcgcagcacggc
gggggcgacgcgcccggggccgccgccgccgctttcccggcctcggccgcctctttctcg
tcgcgctggcgctgcccgagtcactgcatctcggccctcattcagctcaaccacacgcgc
cgcgggcccgccctggaggactgtgactgcgcgcaggacgagaactgcaagtccaccaag
cgcgccattgagccgtgcctgccccggacgagcggcggcggcgcgggcggccccggcgcg
ggcggggtcatgggctgcaccgaggcccggcggcgctgcgaccgcgacagccgctgcaac
ctggcgctgagccgctacctgacctactgcggcaaagtcttcaacgggctgcgctgcacg
gacgaatgccgcaccgtcattgaggacatgctggctatgcccaaggcggcgctgctcaac
gactgcgtgtgcgacggcctcgagcggcccatctgcgagtcggtcaaggagaacatggcc
cgcctgtgcttcggcgccgagctgggcaacggccccggcagcagcggctcggacgggggc
ctggacgactactacgatgaggactacgatgacgagcagcgcaccgggggcgcgggtggt
gagcagccgctggacgacgacgacggcgtcccgcacccaccgcgcccgggcagcggcgct
gctgcatcgggcggccgcggggacctgccctatgggcctgggcgcaggagcagcggcggc
ggcggccgcttggcgccccggggcgcctggaccccactcgcctccatcttgctgctgctg
cttgggccgctcttttag

Protein Sequence

>2619 : length: 345
MVAALLGGGGEARGGTVPGAWLCLMALLQLLGSAPRGSGLAHGRRLICWQALLQCQGEPE
CSYAYNQYAEACAPVLAQHGGGDAPGAAAAAFPASAASFSSRWRCPSHCISALIQLNHTR
RGPALEDCDCAQDENCKSTKRAIEPCLPRTSGGGAGGPGAGGVMGCTEARRRCDRDSRCN
LALSRYLTYCGKVFNGLRCTDECRTVIEDMLAMPKAALLNDCVCDGLERPICESVKENMA
RLCFGAELGNGPGSSGSDGGLDDYYDEDYDDEQRTGGAGGEQPLDDDDGVPHPPRPGSGA
AASGGRGDLPYGPGRRSSGGGGRLAPRGAWTPLASILLLLLGPLF



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