|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 27429 |
Name | HTRA2 |
Synonym | OMI|PARK13|PRSS25;HtrA serine peptidase 2;HTRA2;HtrA serine peptidase 2 |
Definition | HtrA-like serine protease|Omi stress-regulated endoprotease|high temperature requirement protein A2|protease, serine, 25|serine protease 25|serine protease HTRA2, mitochondrial|serine proteinase OMI |
Position | 2p12 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
|
Evidence Status |
Description |
potential | A significant downregulation of HtrA2 transcription is found in the group of borderline tumors of the ovary; HtrA2 may function as a tumor suppressor. |
| More detail of all 1 literatures about HTRA2 | |
|
Pathways and Diseases |
|
Pathway | Parkinson's disease;KEGG PATHWAY;hsa05012 |
Disease | Parkinson's disease;KEGG DISEASE;H00057 |
Disease | Renal Cell cancer;FunDO |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | Parkinson disease;FunDO |
Disease | Neurodegenerative diseases;KEGG DISEASE |
Disease | Parkinson disease 13;OMIM |
Disease | Colon cancer;FunDO |
Disease | Common wart;FunDO |
|
External Links |
|
Links to Entrez Gene | 27429 |
Links to all GeneRIF Items | 27429 |
Links to iHOP | 27429 |
|
Sequence Information |
|
Nucleotide Sequence |
>27429 : length: 1377 atggctgcgccgagggcggggcggggtgcaggctggagccttcgggcatggcgggctttg gggggcattcgctgggggaggagaccccgtttgacccctgacctccgggccctgctgacg tcaggaacttctgacccccgggcccgagtgacttatgggacccccagtctctgggcccgg ttgtctgttggggtcactgaaccccgagcatgcctgacgtctgggaccccgggtccccgg gcacaactgactgcggtgaccccagataccaggacccgggaggcctcagagaactctgga acccgttcgcgcgcgtggctggcggtggcgctgggcgctgggggggcagtgctgttgttg ttgtggggcgggggtcggggtcctccggccgtcctcgccgccgtccctagcccgccgccc gcttctccccggagtcagtacaacttcatcgcagatgtggtggagaagacagcacctgcc gtggtctatatcgagatcctggaccggcaccctttcttgggccgcgaggtccctatctcg aacggctcaggattcgtggtggctgccgatgggctcattgtcaccaacgcccatgtggtg gctgatcggcgcagagtccgtgtgagactgctaagcggcgacacgtatgaggccgtggtc acagctgtggatcccgtggcagacatcgcaacgctgaggattcagactaaggagcctctc cccacgctgcctctgggacgctcagctgatgtccggcaaggggagtttgttgttgccatg ggaagtccctttgcactgcagaacacgatcacatccggcattgttagctctgctcagcgt ccagccagagacctgggactcccccaaaccaatgtggaatacattcaaactgatgcagct attgattttggaaactctggaggtcccctggttaacctggatggggaggtgattggagtg aacaccatgaaggtcacagctggaatctcctttgccatcccttctgatcgtcttcgagag tttctgcatcgtggggaaaagaagaattcctcctccggaatcagtgggtcccagcggcgc tacattggggtgatgatgctgaccctgagtcccagcatccttgctgaactacagcttcga gaaccaagctttcccgatgttcagcatggtgtactcatccataaagtcatcctgggctcc cctgcacaccgggctggtctgcggcctggtgatgtgattttggccattggggagcagatg gtacaaaatgctgaagatgtttatgaagctgttcgaacccaatcccagttggcagtgcag atccggcggggacgagaaacactgaccttatatgtgacccctgaggtcacagaatga |
Protein Sequence |
>27429 : length: 458 MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR LSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL LWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE |