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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 28996 |
Name | HIPK2 |
Synonym | PRO0593;homeodomain interacting protein kinase 2;HIPK2;homeodomain interacting protein kinase 2 |
Definition | hHIPk2|homeodomain-interacting protein kinase 2 |
Position | 7q32-q34 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | HIPK2 is a tumor suppressor that controls proliferation by antagonizing LEF1/beta-catenin-mediated transcription. |
| More detail of all 1 literatures about HIPK2 | |
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Pathways and Diseases |
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Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | p53 pathway;PID Curated;200175 |
Disease | Brain tumor;FunDO |
Disease | Yersinia infection;FunDO |
Disease | Leukoencephalopathy;FunDO |
Disease | Leukemia;FunDO |
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External Links |
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Links to Entrez Gene | 28996 |
Links to all GeneRIF Items | 28996 |
Links to iHOP | 28996 |
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Sequence Information |
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Nucleotide Sequence |
>28996 : length: 3516 atggcccccgtgtacgaaggtatggcctcacatgtgcaagttttctcccctcacaccctt caatcaagtgccttctgtagtgtgaagaaactgaaaatagagccgagttccaactgggac atgactgggtacggctcccacagcaaagtgtatagccagagcaagaacatccccctgtcg cagccagccaccacaaccgtcagcacctccttgccggtcccaaacccaagcctaccttac gagcagaccatcgtcttcccaggaagcaccgggcacatcgtggtcacctcagcaagcagc acttctgtcaccgggcaagtcctcggcggaccacacaacctaatgcgtcgaagcactgtg agcctccttgatacctaccaaaaatgtggactcaagcgtaagagcgaggagatcgagaac acaagcagcgtgcagatcatcgaggagcatccacccatgattcagaataatgcaagcggg gccactgtcgccactgccaccacgtctactgccacctccaaaaacagcggctccaacagc gagggcgactatcagctggtgcagcatgaggtgctgtgctccatgaccaacacctacgag gtcttagagttcttgggccgagggacgtttgggcaagtggtcaagtgctggaaacggggc accaatgagatcgtagccatcaagatcctgaagaaccacccatcctatgcccgacaaggt cagattgaagtgagcatcctggcccggttgagcacggagagtgccgatgactataacttc gtccgggcctacgaatgcttccagcacaagaaccacacgtgcttggtcttcgagatgttg gagcagaacctctatgactttctgaagcaaaacaagtttagccccttgcccctcaaatac attcgcccagttctccagcaggtagccacagccctgatgaaactcaaaagcctaggtctt atccacgctgacctcaaaccagaaaacatcatgctggtggatccatctagacaaccatac agagtcaaggtcatcgactttggttcagccagccacgtctccaaggctgtgtgctccacc tacttgcagtccagatattacagggcccctgagatcatccttggtttaccattttgtgag gcaattgacatgtggtccctgggctgtgttattgcagaattgttcctgggttggccgtta tatccaggagcttcggagtatgatcagattcggtatatttcacaaacacagggtttgcct gctgaatatttattaagcgccgggacaaagacaactaggtttttcaaccgtgacacggac tcaccatatcctttgtggagactgaagacaccagatgaccatgaagcagagacagggatt aagtcaaaagaagcaagaaagtacattttcaactgtttagatgatatggcccaggtgaac atgacgacagatttggaagggagcgacatgttggtagaaaaggctgaccggcgggagttc attgacctgttgaagaagatgctgaccattgatgctgacaagagaatcactccaatcgaa accctgaaccatccctttgtcaccatgacacacttactcgattttccccacagcacacac gtcaaatcatgtttccagaacatggagatctgcaagcgtcgggtgaatatgtatgacacg gtgaaccagagcaaaacccctttcatcacgcacgtggcccccagcacgtccaccaacctg accatgacctttaacaaccagctgaccactgtccacaaccagccctcagcggcatccatg gctgcagtggcccagcggagcatgcccctgcagacaggaacagcccagatttgtgcccgg cctgacccgttccagcaagctctcatcgtgtgtccccccggcttccaaggcttgcaggcc tctccctctaagcacgctggctactcggtgcgaatggaaaatgcagttcccatcgtcact caagccccaggagctcagcctcttcagatccaaccaggtctgcttgcccagcaggcttgg ccaagtgggacccagcagatcctgcttcccccagcatggcagcaactgactggagtggcc acccacacatcagtgcagcatgccaccgtgattcccgagaccatggcaggcacccagcag ctggcggactggagaaatacgcatgctcacggaagccattataatcccatcatgcagcag cctgcactattgaccggtcatgtgacccttccagcagcacagcccttaaatgtgggtgtg gcccacgtgatgcggcagcagccaaccagcaccacctcctcccggaagagtaagcagcac cagtcatctgtgagaaatgtctccacctgtgaggtgtcctcctctcaggccatcagctcc ccacagcgatccaagcgtgtcaaggagaacacacctccccgctgtgccatggtgcacagt agcccggcctgcagcacctcggtcacctgtgggtggggcgacgtggcctccagcaccacc cgggaacggcagcggcagacaattgtcattcccgacactcccagccccacggtcagcgtc atcaccatcagcagtgacacggacgaggaggaggaacagaaacacgcccccaccagcact gtctccaagcaaagaaaaaacgtcatcagctgtgtcacagtccacgactccccctactcc gactcctccagcaacaccagcccctactccgtgcagcagcgtgctgggcacaacaatgcc aatgcctttgacaccaaggggagcctggagaatcactgcacggggaacccccgaaccatc atcgtgccacccctgaaaacccaggccagcgaagtattggtggagtgtgatagcctggtg ccagtcaacaccagtcaccactcgtcctcctacaagtccaagtcctccagcaacgtgacc tccaccagcggtcactcttcagggagctcatctggagccatcacctaccggcagcagcgg ccgggcccccacttccagcagcagcagccactcaatctcagccaggctcagcagcacatc accacggaccgcactgggagccaccgaaggcagcaggcctacatcactcccaccatggcc caggctccgtactccttcccgcacaacagccccagccacggcactgtgcacccgcatctg gctgcagccgctgccgctgcccacctccccacccagccccacctctacacctacactgcg ccggcggccctgggctccaccggcaccgtggcccacctggtggcctcgcaaggctctgcg cgccacaccgtgcagcacactgcctacccagccagcatcgtccaccaggtccccgtgagc atgggcccccgggtcctgccctcgcccaccatccacccgagtcagtatccagcccaattt gcccaccagacctacatcagcgcctcgccagcctccaccgtctacactggatacccactg agccccgccaaggtcaaccagtacccttacatataa |
Protein Sequence |
>28996 : length: 1171 MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLS QPATTTVSTSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTV SLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNS EGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQG QIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKY IRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCST YLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP AEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVN MTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTH VKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQPSAASM AAVAQRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVT QAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQ LADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQH QSSVRNVSTCEVSSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSVTCGWGDVASSTT RERQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYS DSSSNTSPYSVQQRAGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLV PVNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQHI TTDRTGSHRRQQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTA PAALGSTGTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQF AHQTYISASPASTVYTGYPLSPAKVNQYPYI |