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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 28996 |
Name | HIPK2 |
Synonymous | PRO0593;homeodomain interacting protein kinase 2;HIPK2;homeodomain interacting protein kinase 2 |
Definition | hHIPk2|homeodomain-interacting protein kinase 2 |
Position | 7q32-q34 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
hipk2(h) + p53(h) <==> hipk2(h):p53(h) (binding) | hipk2(h) + PML-3(h) <==> hipk2(h):PML-3(h) (binding) | hipk2(h) + CBP(h) <==> hipk2(h):CBP(h) (binding) | p73alpha(h) + hipk2(h) <==> p73alpha(h):hipk2(h) (binding) | p73beta(h) + hipk2(h) <==> p73beta(h):hipk2(h) (binding) | p63alpha(h) + hipk2(h) <==> p63alpha(h):hipk2(h) (binding) | p63gamma(h) + hipk2(h) <==> p63gamma(h):hipk2(h) (binding) | AML1b(h) + hipk2(h) <==> AML1b(h):hipk2(h) (binding) | hipk2(h) + ATP --> hipk2(h){p} + ADP (phosphorylation; automodification) | hipk2(h) + p300(m.s.) <==> hipk2(h):p300(m.s.) (binding) | hipk2(h) --> hipk2(h) (expression). | AML1b(h) + 2 ATP --hipk2(h)--> AML1b(h){pS249}{pS276} + 2 ADP (phosphorylation) | p300(m.s.) + ATP --hipk2(h)--> p300(m.s.){p} + ADP (phosphorylation) | MOZ(h) + ATP --hipk2(h)--> MOZ(h){p} + ADP (phosphorylation) | HMGIY-isoform1(h) + 3 ATP --hipk2(h)--> HMGIY-isoform1(h){pS36}{pT53}{pT78} + 3 ADP (phosphorylation) | HMGIY-isoform2(h) + 2 ATP --hipk2(h)--> HMGIY-isoform2(h){pT42}{pT67} + 2 ADP (phosphorylation) | HIPK2(h) --> hipk2-isoform1(h) (expression). | HIPK2(h) --> hipk2-isoform2(h) (expression). | HIPK2(h) --> hipk2-isoform3(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
32 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 1191 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO) (Bysimilarity). | Swiss-Prot 53.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
There is no record for HIPK2 |