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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 3487 |
Name | IGFBP4 |
Synonym | BP-4|HT29-IGFBP|IBP4|IGFBP-4;insulin-like growth factor binding protein 4;IGFBP4;insulin-like growth factor binding protein 4 |
Definition | IBP-4|IGF-binding protein 4|insulin-like growth factor-binding protein 4 |
Position | 17q12-q21.1 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | conclusion: decreased IGFBP-4 tumor expression might be a step in the progression from primary to metastatic melanoma; data lend support to a recently-described novel tumor suppressor role of secreting IGFBPs in melanoma. |
| More detail of all 1 literatures about IGFBP4 | |
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Pathways and Diseases |
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Pathway | Wnt signaling network;PID Curated;200055 |
Pathway | Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs);PID Reactome;500133 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 3487 |
Links to all GeneRIF Items | 3487 |
Links to iHOP | 3487 |
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Sequence Information |
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Nucleotide Sequence |
>3487 : length: 777 atgctgcccctctgcctcgtggccgccctgctgctggccgccgggcccgggccgagcctg ggcgacgaagccatccactgcccgccctgctccgaggagaagctggcgcgctgccgcccc cccgtgggctgcgaggagctggtgcgagagccgggctgcggctgttgcgccacttgcgcc ctgggcttggggatgccctgcggggtgtacaccccccgttgcggctcgggcctgcgctgc tacccgccccgaggggtggagaagcccctgcacacactgatgcacgggcaaggcgtgtgc atggagctggcggagatcgaggccatccaggaaagcctgcagccctctgacaaggacgag ggtgaccaccccaacaacagcttcagcccctgtagcgcccatgaccgcaggtgcctgcag aagcacttcgccaaaattcgagaccggagcaccagtgggggcaagatgaaggtcaatggg gcgccccgggaggatgcccggcctgtgccccagggctcctgccagagcgagctgcaccgg gcgctggagcggctggccgcttcacagagccgcacccacgaggacctctacatcatcccc atccccaactgcgaccgcaacggcaacttccaccccaagcagtgtcacccagctctggat gggcagcgtggcaagtgctggtgtgtggaccggaagacgggggtgaagcttccggggggc ctggagccaaagggggagctggactgccaccagctggctgacagctttcgagagtga |
Protein Sequence |
>3487 : length: 258 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG LEPKGELDCHQLADSFRE |