Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

3488

Name

IGFBP5

Synonym

IBP5;insulin-like growth factor binding protein 5;IGFBP5;insulin-like growth factor binding protein 5

Definition

IBP-5|IGF-binding protein 5|IGFBP-5|insulin-like growth factor-binding protein 5

Position

2q33-q36

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

IGFBP-5 expression prevented tumor growth and inhibited tumor vascularity in a xenograft model of human ovarian cancer. These results are the first evidence showing that IGFBP-5 plays a role as tumor suppressor by inhibiting angiogenesis.
More detail of all 1 literatures about IGFBP5

Pathways and Diseases

Pathway

Diabetes pathways;Reactome;REACT:15380

Pathway

Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs);PID Reactome;500133

Disease

Hamman-Rich syndrome;FunDO

Disease

Cancer;FunDO

External Links

Links to Entrez Gene

3488

Links to all GeneRIF Items

3488

Links to iHOP

3488

Sequence Information

Nucleotide Sequence

>3488 : length: 819
atggtgttgctcaccgcggtcctcctgctgctggccgcctatgcggggccggcccagagc
ctgggctccttcgtgcactgcgagccctgcgacgagaaagccctctccatgtgccccccc
agccccctgggctgcgagctggtcaaggagccgggctgcggctgctgcatgacctgcgcc
ctggccgaggggcagtcgtgcggcgtctacaccgagcgctgcgcccaggggctgcgctgc
ctcccccggcaggacgaggagaagccgctgcacgccctgctgcacggccgcggggtttgc
ctcaacgaaaagagctaccgcgagcaagtcaagatcgagagagactcccgtgagcacgag
gagcccaccacctctgagatggccgaggagacctactcccccaagatcttccggcccaaa
cacacccgcatctccgagctgaaggctgaagcagtgaagaaggaccgcagaaagaagctg
acccagtccaagtttgtcgggggagccgagaacactgcccacccccggatcatctctgca
cctgagatgagacaggagtctgagcagggcccctgccgcagacacatggaggcttccctg
caggagctcaaagccagcccacgcatggtgccccgtgctgtgtacctgcccaattgtgac
cgcaaaggattctacaagagaaagcagtgcaaaccttcccgtggccgcaagcgtggcatc
tgctggtgcgtggacaagtacgggatgaagctgccaggcatggagtacgttgacggggac
tttcagtgccacaccttcgacagcagcaacgttgagtga

Protein Sequence

>3488 : length: 272
MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA
LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE
EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA
PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI
CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE



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