Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

4118

Name

MAL

Synonym

-;mal, T-cell differentiation protein;MAL;mal, T-cell differentiation protein

Definition

T-cell differentiation protein MAL|T-lymphocyte maturation-associated protein|myelin and lymphocyte protein

Position

2cen-q13

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 2 PubMed records as below.

Evidence Status

Description

potential

"Data suggest that the epigenetic inactivation of MAL, as a candidate tumor suppressor gene, can contribute to human epithelial cell carcinoma and may be served as a biomarker in HNSCC."

potential

The mal gene which is switched-off in all esophageal squamous cell carcinoma samples can be considered as a tumor suppressor gene.
More detail of all 2 literatures about MAL

Pathways and Diseases

Pathway

role of mal in rho-mediated activation of srf;PID BioCarta;100114

Disease

Adenoma;FunDO

Disease

Esophagus cancer;FunDO

Disease

Rheumatoid arthritis;FunDO

Disease

Prostate cancer;FunDO

External Links

Links to Entrez Gene

4118

Links to all GeneRIF Items

4118

Links to iHOP

4118

Sequence Information

Nucleotide Sequence

>4118 : length: 462
atggcccccgcagcggcgacggggggcagcaccctgcccagtggcttctcggtcttcacc
accttgcccgacttgctcttcatctttgagtttatcttcgggggcctggtgtggatcctg
gtggcctcctccctggtgccctggcccctggtccagggctgggtgatgttcgtgtctgtg
ttctgcttcgtggccaccaccaccttgatcatcctgtacataattggagcccacggtgga
gagacttcctgggtcaccttggacgcagcctaccactgcaccgctgccctcttttacctc
agcgcctcagtcctggaggccctggccaccatcacgatgcaagacggcttcacctacagg
cactaccatgaaaacattgctgccgtggtgttctcctacatagccactctgctctacgtg
gtccatgcggtgttctctttaatcagatggaagtcttcataa

Protein Sequence

>4118 : length: 153
MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV
FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR
HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS



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