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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 4303 |
Name | FOXO4 |
Synonym | AFX|AFX1|MLLT7;forkhead box O4;FOXO4;forkhead box O4 |
Definition | fork head domain transcription factor AFX1|forkhead box protein O4|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7 |
Position | Xq13.1 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | FOXO4 may function as a tumor suppressor in the development and progression of colorectal cancer. |
| More detail of all 1 literatures about FOXO4 | |
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Pathways and Diseases |
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Pathway | Class I PI3K signaling events mediated by Akt;PID Curated;200169 |
Pathway | Signaling events mediated by HDAC Class III;PID Curated;200020 |
Pathway | Regulation of nuclear SMAD2/3 signaling;PID Curated;200002 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | ras signaling pathway;PID BioCarta;100047 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | akt signaling pathway;PID BioCarta;100245 |
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External Links |
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Links to Entrez Gene | 4303 |
Links to all GeneRIF Items | 4303 |
Links to iHOP | 4303 |
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Sequence Information |
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Nucleotide Sequence |
>4303 : length: 1353 atggatccggggaatgagaattcagccacagaggctgccgcgatcatagacctagatccc gacttcgaaccccagagccgtccccgctcctgcacctggccccttccccgaccagagatc gctaaccagccgtccgagccgcccgaggtggagccagatctgggggaaaaggccattgaa agcgccccggagaagcgactgacacttgcccagatctacgagtggatggtccgtactgta ccctacttcaaggacaagggtgacagcaacagctcagcaggatggaagaactcgatccgc cacaacctgtccctgcacagcaagttcatcaaggttcacaacgaggccaccggcaaaagc tcttggtggatgctgaaccctgagggaggcaagagcggcaaagccccccgccgccgggcc gcctccatggatagcagcagcaagctgctccggggccgcagtaaagcccccaagaagaaa ccatctgtgctgccagctccacccgaaggtgccactccaacgagccctgtcggccacttt gccaagtggtcaggcagcccttgctctcgaaaccgtgaagaagccgatatgtggaccacc ttccgtccacgaagcagttcaaatgccagcagtgtcagcacccggctgtcccccttgagg ccagagtctgaggtgctggcggaggaaataccagcttcagtcagcagttatgcagggggt gtccctcccaccctcaatgaaggtctagagctgttagatgggctcaatctcacctcttcc cattccctgctatctcggagtggtctctctggcttctctttgcagcatcctggggttacc ggccccttacacacctacagcagctcccttttcagcccagcagaggggcccctgtcagca ggagaagggtgcttctccagctcccaggctctggaggccctgctcacctctgatacgcca ccaccccctgctgacgtcctcatgacccaggtagatcccattctgtcccaggctccgact cttctgttgctgggggggcttccttcctccagtaagctggccacgggcgtcggcctgtgt cccaagcccctagaggctccaggccccagcagtctggttcccaccctttctatgatagca ccacctccagtcatggcaagtgcccccatccccaaggctctggggactcctgtgctcaca ccccctactgaagctgcaagccaagacagaatgcctcaggatctagatcttgatatgtat atggagaacctggagtgtgacatggataacatcatcagtgacctcatggatgagggcgag ggactggacttcaactttgagccagatccctga |
Protein Sequence |
>4303 : length: 450 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKAIE SAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKS SWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHF AKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGG VPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSA GEGCFSSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLC PKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMY MENLECDMDNIISDLMDEGEGLDFNFEPDP |