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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5310 |
Name | PKD1 |
Synonym | PBP|Pc-1|TRPP1;polycystic kidney disease 1 (autosomal dominant);PKD1;polycystic kidney disease 1 (autosomal dominant) |
Definition | autosomal dominant polycystic kidney disease 1 protein|polycystic kidney disease-associated protein|polycystin 1|polycystin-1|transient receptor potential cation channel, subfamily P, member 1 |
Position | 16p13.3 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | Data suggest that PKD1 may act as a novel member of the tumor suppressor family of genes. |
| More detail of all 1 literatures about PKD1 | |
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External Links |
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Links to Entrez Gene | 5310 |
Links to all GeneRIF Items | 5310 |
Links to iHOP | 5310 |
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Sequence Information |
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Nucleotide Sequence |
>5310 : length: 12909 atgccgcccgccgcgcccgcccgcctggcgctggccctgggcctgggcctgtggctcggg gcgctggcggggggccccgggcgcggctgcgggccctgcgagcccccctgcctctgcggc ccagcgcccggcgccgcctgccgcgtcaactgctcgggccgcgggctgcggacgctcggt cccgcgctgcgcatccccgcggacgccacagcgctagacgtctcccacaacctgctccgg gcgctggacgttgggctcctggcgaacctctcggcgctggcagagctggatataagcaac aacaagatttctacgttagaagaaggaatatttgctaatttatttaatttaagtgaaata aacctgagtgggaacccgtttgagtgtgactgtggcctggcgtggctgccgcgatgggcg gaggagcagcaggtgcgggtggtgcagcccgaggcagccacgtgtgctgggcctggctcc ctggctggccagcctctgcttggcatccccttgctggacagtggctgtggtgaggagtat gtcgcctgcctccctgacaacagctcaggcaccgtggcagcagtgtccttttcagctgcc cacgaaggcctgcttcagccagaggcctgcagcgccttctgcttctccaccggccagggc ctcgcagccctctcggagcagggctggtgcctgtgtggggcggcccagccctccagtgcc tcctttgcctgcctgtccctctgctccggccccccgccacctcctgcccccacctgtagg ggccccaccctcctccagcacgtcttccctgcctccccaggggccaccctggtggggccc cacggacctctggcctctggccagctagcagccttccacatcgctgccccgctccctgtc actgccacacgctgggacttcggagacggctccgccgaggtggatgccgctgggccggct gcctcgcatcgctatgtgctgcctgggcgctatcacgtgacggccgtgctggccctgggg gccggctcagccctgctggggacagacgtgcaggtggaagcggcacctgccgccctggag ctcgtgtgcccgtcctcggtgcagagtgacgagagccttgacctcagcatccagaaccgc ggtggttcaggcctggaggccgcctacagcatcgtggccctgggcgaggagccggcccga gcggtgcacccgctctgcccctcggacacggagatcttccctggcaacgggcactgctac cgcctggtggtggagaaggcggcctggctgcaggcgcaggagcagtgtcaggcctgggcc ggggccgccctggcaatggtggacagtcccgccgtgcagcgcttcctggtctcccgggtc accaggagcctagacgtgtggatcggcttctcgactgtgcagggggtggaggtgggccca gcgccgcagggcgaggccttcagcctggagagctgccagaactggctgcccggggagcca cacccagccacagccgagcactgcgtccggctcgggcccaccgggtggtgtaacaccgac ctgtgctcagcgccgcacagctacgtctgcgagctgcagcccggaggcccagtgcaggat gccgagaacctcctcgtgggagcgcccagtggggacctgcagggacccctgacgcctctg gcacagcaggacggcctctcagccccgcacgagcccgtggaggtcatggtattcccgggc ctgcgtctgagccgtgaagccttcctcaccacggccgaatttgggacccaggagctccgg cggcccgcccagctgcggctgcaggtgtaccggctcctcagcacagcagggaccccggag aacggcagcgagcctgagagcaggtccccggacaacaggacccagctggcccccgcgtgc atgccagggggacgctggtgccctggagccaacatctgcttgccgctggacgcctcctgc cacccccaggcctgcgccaatggctgcacgtcagggccagggctacccggggccccctat gcgctatggagagagttcctcttctccgttcccgcggggccccccgcgcagtactcggtc accctccacggccaggatgtcctcatgctccctggtgacctcgttggcttgcagcacgac gctggccctggcgccctcctgcactgctcgccggctcccggccaccctggtccccaggcc ccgtacctctccgccaacgcctcgtcatggctgccccacttgccagcccagctggagggc acttgggcctgccctgcctgtgccctgcggctgcttgcagccacggaacagctcaccgtg ctgctgggcttgaggcccaaccctggactgcggctgcctgggcgctatgaggtccgggca gaggtgggcaatggcgtgtccaggcacaacctctcctgcagctttgacgtggtctcccca gtggctgggctgcgggtcatctaccctgccccccgcgacggccgcctctacgtgcccacc aacggctcagccttggtgctccaggtggactctggtgccaacgccacggccacggctcgc tggcctgggggcagtgtcagcgcccgctttgagaatgtctgccctgccctggtggccacc ttcgtgcccggctgcccctgggagaccaacgataccctgttctcagtggtagcactgccg tggctcagtgagggggagcacgtggtggacgtggtggtggaaaacagcgccagccgggcc aacctcagcctgcgggtgacggcggaggagcccatctgtggcctccgcgccacgcccagc cccgaggcccgtgtactgcagggagtcctagtgaggtacagccccgtggtggaggccggc tcggacatggtcttccggtggaccatcaacgacaagcagtccctgaccttccagaacgtg gtcttcaatgtcatttatcagagcgcggcggtcttcaagctctcactgacggcctccaac cacgtgagcaacgtcaccgtgaactacaacgtaaccgtggagcggatgaacaggatgcag ggtctgcaggtctccacagtgccggccgtgctgtcccccaatgccacgctagcactgacg gcgggcgtgctggtggactcggccgtggaggtggccttcctgtggacctttggggatggg gagcaggccctccaccagttccagcctccgtacaacgagtccttcccggttccagacccc tcggtggcccaggtgctggtggagcacaatgtcatgcacacctacgctgccccaggtgag tacctcctgaccgtgctggcatctaatgccttcgagaacctgacgcagcaggtgcctgtg agcgtgcgcgcctccctgccctccgtggctgtgggtgtgagtgacggcgtcctggtggcc ggccggcccgtcaccttctacccgcacccgctgccctcgcctgggggtgttctttacacg tgggacttcggggacggctcccctgtcctgacccagagccagccggctgccaaccacacc tatgcctcgaggggcacctaccacgtgcgcctggaggtcaacaacacggtgagcggtgcg gcggcccaggcggatgtgcgcgtctttgaggagctccgcggactcagcgtggacatgagc ctggccgtggagcagggcgcccccgtggtggtcagcgccgcggtgcagacgggcgacaac atcacgtggaccttcgacatgggggacggcaccgtgctgtcgggcccggaggcaacagtg gagcatgtgtacctgcgggcacagaactgcacagtgaccgtgggtgcggccagccccgcc ggccacctggcccggagcctgcacgtgctggtcttcgtcctggaggtgctgcgcgttgaa cccgccgcctgcatccccacgcagcctgacgcgcggctcacggcctacgtcaccgggaac ccggcccactacctcttcgactggaccttcggggatggctcctccaacacgaccgtgcgg gggtgcccgacggtgacacacaacttcacgcggagcggcacgttccccctggcgctggtg ctgtccagccgcgtgaacagggcgcattacttcaccagcatctgcgtggagccagaggtg ggcaacgtcaccctgcagccagagaggcagtttgtgcagctcggggacgaggcctggctg gtggcatgtgcctggcccccgttcccctaccgctacacctgggactttggcaccgaggaa gccgcccccacccgtgccaggggccctgaggtgacgttcatctaccgagacccaggctcc tatcttgtgacagtcaccgcgtccaacaacatctctgctgccaatgactcagccctggtg gaggtgcaggagcccgtgctggtcaccagcatcaaggtcaatggctcccttgggctggag ctgcagcagccgtacctgttctctgctgtgggccgtgggcgccccgccagctacctgtgg gatctgggggacggtgggtggctcgagggtccggaggtcacccacgcttacaacagcaca ggtgacttcaccgttagggtggccggctggaatgaggtgagccgcagcgaggcctggctc aatgtgacggtgaagcggcgcgtgcgggggctcgtcgtcaatgcaagccgcacggtggtg cccctgaatgggagcgtgagcttcagcacgtcgctggaggccggcagtgatgtgcgctat tcctgggtgctctgtgaccgctgcacgcccatccctgggggtcctaccatctcttacacc ttccgctccgtgggcaccttcaatatcatcgtcacggctgagaacgaggtgggctccgcc caggacagcatcttcgtctatgtcctgcagctcatagaggggctgcaggtggtgggcggt ggccgctacttccccaccaaccacacggtacagctgcaggccgtggttagggatggcacc aacgtctcctacagctggactgcctggagggacaggggcccggccctggccggcagcggc aaaggcttctcgctcaccgtgctcgaggccggcacctaccatgtgcagctgcgggccacc aacatgctgggcagcgcctgggccgactgcaccatggacttcgtggagcctgtggggtgg ctgatggtggccgcctccccgaacccagctgccgtcaacacaagcgtcaccctcagtgcc gagctggctggtggcagtggtgtcgtatacacttggtccttggaggaggggctgagctgg gagacctccgagccatttaccacccatagcttccccacacccggcctgcacttggtcacc atgacggcagggaacccgctgggctcagccaacgccaccgtggaagtggatgtgcaggtg cctgtgagtggcctcagcatcagggccagcgagcccggaggcagcttcgtggcggccggg tcctctgtgcccttttgggggcagctggccacgggcaccaatgtgagctggtgctgggct gtgcccggcggcagcagcaagcgtggccctcatgtcaccatggtcttcccggatgctggc accttctccatccggctcaatgcctccaacgcagtcagctgggtctcagccacgtacaac ctcacggcggaggagcccatcgtgggcctggtgctgtgggccagcagcaaggtggtggcg cccgggcagctggtccattttcagatcctgctggctgccggctcagctgtcaccttccgc ctgcaggtcggcggggccaaccccgaggtgctccccgggccccgtttctcccacagcttc ccccgcgtcggagaccacgtggtgagcgtgcggggcaaaaaccacgtgagctgggcccag gcgcaggtgcgcatcgtggtgctggaggccgtgagtgggctgcaggtgcccaactgctgc gagcctggcatcgccacgggcactgagaggaacttcacagcccgcgtgcagcgcggctct cgggtcgcctacgcctggtacttctcgctgcagaaggtccagggcgactcgctggtcatc ctgtcgggccgcgacgtcacctacacgcccgtggccgcggggctgttggagatccaggtg cgcgccttcaacgccctgggcagtgagaaccgcacgctggtgctggaggttcaggacgcc gtccagtatgtggccctgcagagcggcccctgcttcaccaaccgctcggcgcagtttgag gccgccaccagccccagcccccggcgtgtggcctaccactgggactttggggatgggtcg ccagggcaggacacagatgagcccagggccgagcactcctacctgaggcctggggactac cgcgtgcaggtgaacgcctccaacctggtgagcttcttcgtggcgcaggccacggtgacc gtccaggtgctggcctgccgggagccggaggtggacgtggtcctgcccctgcaggtgctg atgcggcgatcacagcgcaactacttggaggcccacgttgacctgcgcgactgcgtcacc taccagactgagtaccgctgggaggtgtatcgcaccgccagctgccagcggccggggcgc ccagcgcgtgtggccctgcccggcgtggacgtgagccggcctcggctggtgctgccgcgg ctggcgctgcctgtggggcactactgctttgtgtttgtcgtgtcatttggggacacgcca ctgacacagagcatccaggccaatgtgacggtggcccccgagcgcctggtgcccatcatt gagggtggctcataccgcgtgtggtcagacacacgggacctggtgctggatgggagcgag tcctacgaccccaacctggaggacggcgaccagacgccgctcagtttccactgggcctgt gtggcttcgacacagagggaggctggcgggtgtgcgctgaactttgggccccgcgggagc agcacggtcaccattccacgggagcggctggcggctggcgtggagtacaccttcagcctg accgtgtggaaggccggccgcaaggaggaggccaccaaccagacggtgctgatccggagt ggccgggtgcccattgtgtccttggagtgtgtgtcctgcaaggcacaggccgtgtacgaa gtgagccgcagctcctacgtgtacttggagggccgctgcctcaattgcagcagcggctcc aagcgagggcggtgggctgcacgtacgttcagcaacaagacgctggtgctggatgagacc accacatccacgggcagtgcaggcatgcgactggtgctgcggcggggcgtgctgcgggac ggcgagggatacaccttcacgctcacggtgctgggccgctctggcgaggaggagggctgc gcctccatccgcctgtcccccaaccgcccgccgctggggggctcttgccgcctcttccca ctgggcgctgtgcacgccctcaccaccaaggtgcacttcgaatgcacgggctggcatgac gcggaggatgctggcgccccgctggtgtacgccctgctgctgcggcgctgtcgccagggc cactgcgaggagttctgtgtctacaagggcagcctctccagctacggagccgtgctgccc ccgggtttcaggccacacttcgaggtgggcctggccgtggtggtgcaggaccagctggga gccgctgtggtcgccctcaacaggtctttggccatcaccctcccagagcccaacggcagc gcaacggggctcacagtctggctgcacgggctcaccgctagtgtgctcccagggctgctg cggcaggccgatccccagcacgtcatcgagtactcgttggccctggtcaccgtgctgaac gagtacgagcgggccctggacgtggcggcagagcccaagcacgagcggcagcaccgagcc cagatacgcaagaacatcacggagactctggtgtccctgagggtccacactgtggatgac atccagcagatcgctgctgcgctggcccagtgcatggggcccagcagggagctcgtatgc cgctcgtgcctgaagcagacgctgcacaagctggaggccatgatgctcatcctgcaggca gagaccaccgcgggcaccgtgacgcccaccgccatcggagacagcatcctcaacatcaca ggagacctcatccacctggccagctcggacgtgcgggcaccacagccctcagagctggga gccgagtcaccatctcggatggtggcgtcccaggcctacaacctgacctctgccctcatg cgcatcctcatgcgctcccgcgtgctcaacgaggagcccctgacgctggcgggcgaggag atcgtggcccagggcaagcgctcggacccgcggagcctgctgtgctatggcggcgcccca gggcctggctgccacttctccatccccgaggctttcagcggggccctggccaacctcagt gacgtggtgcagctcatctttctggtggactccaatccctttccctttggctatatcagc aactacaccgtctccaccaaggtggcctcgatggcattccagacacaggccggcgcccag atccccatcgagcggctggcctcagagcgcgccatcaccgtgaaggtgcccaacaactcg gactgggctgcccggggccaccgcagctccgccaactccgccaactccgttgtggtccag ccccaggcctccgtcggtgctgtggtcaccctggacagcagcaaccctgcggccgggctg catctgcagctcaactatacgctgctggacggccactacctgtctgaggaacctgagccc tacctggcagtctacctacactcggagccccggcccaatgagcacaactgctcggctagc aggaggatccgcccagagtcactccagggtgctgaccaccggccctacaccttcttcatt tccccggggagcagagacccagcggggagttaccatctgaacctctccagccacttccgc tggtcggcgctgcaggtgtccgtgggcctgtacacgtccctgtgccagtacttcagcgag gaggacatggtgtggcggacagaggggctgctgcccctggaggagacctcgccccgccag gccgtctgcctcacccgccacctcaccgccttcggcgccagcctcttcgtgcccccaagc catgtccgctttgtgtttcctgagccgacagcggatgtaaactacatcgtcatgctgaca tgtgctgtgtgcctggtgacctacatggtcatggccgccatcctgcacaagctggaccag ttggatgccagccggggccgcgccatccctttctgtgggcagcggggccgcttcaagtac gagatcctcgtcaagacaggctggggccggggctcaggtaccacggcccacgtgggcatc atgctgtatggggtggacagccggagcggccaccggcacctggacggcgacagagccttc caccgcaacagcctggacatcttccggatcgccaccccgcacagcctgggtagcgtgtgg aagatccgagtgtggcacgacaacaaagggctcagccctgcctggttcctgcagcacgtc atcgtcagggacctgcagacggcacgcagcgccttcttcctggtcaatgactggctttcg gtggagacggaggccaacgggggcctggtggagaaggaggtgctggccgcgagcgacgca gcccttttgcgcttccggcgcctgctggtggctgagctgcagcgtggcttctttgacaag cacatctggctctccatatgggaccggccgcctcgtagccgtttcactcgcatccagagg gccacctgctgcgttctcctcatctgcctcttcctgggcgccaacgccgtgtggtacggg gctgttggcgactctgcctacagcacggggcatgtgtccaggctgagcccgctgagcgtc gacacagtcgctgttggcctggtgtccagcgtggttgtctatcccgtctacctggccatc ctttttctcttccggatgtcccggagcaaggtggctgggagcccgagccccacacctgcc gggcagcaggtgctggacatcgacagctgcctggactcgtccgtgctggacagctccttc ctcacgttctcaggcctccacgctgaggcctttgttggacagatgaagagtgacttgttt ctggatgattctaagagtctggtgtgctggccctccggcgagggaacgctcagttggccg gacctgctcagtgacccgtccattgtgggtagcaatctgcggcagctggcacggggccag gcgggccatgggctgggcccagaggaggacggcttctccctggccagcccctactcgcct gccaaatccttctcagcatcagatgaagacctgatccagcaggtccttgccgagggggtc agcagcccagcccctacccaagacacccacatggaaacggacctgctcagcagcctgtcc agcactcctggggagaagacagagacgctggcgctgcagaggctgggggagctggggcca cccagcccaggcctgaactgggaacagccccaggcagcgaggctgtccaggacaggactg gtggagggtctgcggaagcgcctgctgccggcctggtgtgcctccctggcccacgggctc agcctgctcctggtggctgtggctgtggctgtctcagggtgggtgggtgcgagcttcccc ccgggcgtgagtgttgcgtggctcctgtccagcagcgccagcttcctggcctcattcctc ggctgggagccactgaaggtcttgctggaagccctgtacttctcactggtggccaagcgg ctgcacccggatgaagatgacaccctggtagagagcccggctgtgacgcctgtgagcgca cgtgtgccccgcgtacggccaccccacggctttgcactcttcctggccaaggaagaagcc cgcaaggtcaagaggctacatggcatgctgcggagcctcctggtgtacatgctttttctg ctggtgaccctgctggccagctatggggatgcctcatgccatgggcacgcctaccgtctg caaagcgccatcaagcaggagctgcacagccgggccttcctggccatcacgcggtctgag gagctctggccatggatggcccacgtgctgctgccctacgtccacgggaaccagtccagc ccagagctggggcccccacggctgcggcaggtgcggctgcaggaagcactctacccagac cctcccggccccagggtccacacgtgctcggccgcaggaggcttcagcaccagcgattac gacgttggctgggagagtcctcacaatggctcggggacgtgggcctattcagcgccggat ctgctgggggcatggtcctggggctcctgtgccgtgtatgacagcgggggctacgtgcag gagctgggcctgagcctggaggagagccgcgaccggctgcgcttcctgcagctgcacaac tggctggacaacaggagccgcgctgtgttcctggagctcacgcgctacagcccggccgtg gggctgcacgccgccgtcacgctgcgcctcgagttcccggcggccggccgcgccctggcc gccctcagcgtccgcccctttgcgctgcgccgcctcagcgcgggcctctcgctgcctctg ctcacctcggtgtgcctgctgctgttcgccgtgcacttcgccgtggccgaggcccgtact tggcacagggaagggcgctggcgcgtgctgcggctcggagcctgggcgcggtggctgctg gtggcgctgacggcggccacggcactggtacgcctcgcccagctgggtgccgctgaccgc cagtggacccgtttcgtgcgcggccgcccgcgccgcttcactagcttcgaccaggtggcg cagctgagctccgcagcccgtggcctggcggcctcgctgctcttcctgcttttggtcaag gctgcccagcagctacgcttcgtgcgccagtggtccgtctttggcaagacattatgccga gctctgccagagctcctgggggtcaccttgggcctggtggtgctcggggtagcctacgcc cagctggccatcctgctcgtgtcttcctgtgtggactccctctggagcgtggcccaggcc ctgttggtgctgtgccctgggactgggctctctaccctgtgtcctgccgagtcctggcac ctgtcacccctgctgtgtgtggggctctgggcactgcggctgtggggcgccctacggctg ggggctgttattctccgctggcgctaccacgccttgcgtggagagctgtaccggccggcc tgggagccccaggactacgagatggtggagttgttcctgcgcaggctgcgcctctggatg ggcctcagcaaggtcaaggagttccgccacaaagtccgctttgaagggatggagccgctg ccctctcgctcctccaggggctccaaggtatccccggatgtgcccccacccagcgctggc tccgatgcctcgcacccctccacctcctccagccagctggatgggctgagcgtgagcctg ggccggctggggacaaggtgtgagcctgagccctcccgcctccaagccgtgttcgaggcc ctgctcacccagtttgaccgactcaaccaggccacagaggacgtctaccagctggagcag cagctgcacagcctgcaaggccgcaggagcagccgggcgcccgccggatcttcccgtggc ccatccccgggcctgcggccagcactgcccagccgccttgcccgggccagtcggggtgtg gacctggccactggccccagcaggacaccccttcgggccaagaacaaggtccaccccagc agcacttag |
Protein Sequence |
>5310 : length: 4302 MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLG PALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEI NLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEY VACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSA SFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPV TATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALE LVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCY RLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGP APQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQD AENLLVGAPSGDLQGPLTPLAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELR RPAQLRLQVYRLLSTAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASC HPQACANGCTSGPGLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHD AGPGALLHCSPAPGHPGPQAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTV LLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPT NGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALP WLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAG SDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQ GLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDP SVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVA GRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGA AAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATV EHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGN PAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEV GNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGS YLVTVTASNNISAANDSALVEVQEPVLVTSIKVNGSLGLELQQPYLFSAVGRGRPASYLW DLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVV PLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSA QDSIFVYVLQLIEGLQVVGGGRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDRGPALAGSG KGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSA ELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQV PVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAG TFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFR LQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCC EPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQV RAFNALGSENRTLVLEVQDAVQYVALQSGPCFTNRSAQFEAATSPSPRRVAYHWDFGDGS PGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVL MRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPR LALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSE SYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSSTVTIPRERLAAGVEYTFSL TVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGS KRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGC ASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG HCEEFCVYKGSLSSYGAVLPPGFRPHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGS ATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRA QIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQA ETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALM RILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALANLS DVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNS DWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEP YLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFR WSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPS HVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKY EILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVW KIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDA ALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYG AVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPA GQQVLDIDSCLDSSVLDSSFLTFSGLHAEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWP DLLSDPSIVGSNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGV SSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGL VEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFL GWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEA RKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSE ELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDY DVGWESPHNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHN WLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPL LTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADR QWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCR ALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCPGTGLSTLCPAESWH LSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWM GLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSL GRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPAGSSRG PSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST |