|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5395 |
Name | PMS2 |
Synonym | HNPCC4|PMS2CL|PMSL2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae);PMS2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae) |
Definition | DNA mismatch repair protein PMS2|H_DJ0042M02.9|PMS1 protein homolog 2|mismatch repair endonuclease PMS2 |
Position | 7p22.2 |
Gene Type | protein-coding |
Source | Count: 1; UniProt |
Literature support | Count: 0 PubMed records as below. |
|
Evidence Status |
Description |
| . |
| More detail of all 0 literatures about PMS2 | |
|
Pathways and Diseases |
|
Pathway | Mismatch repair;KEGG PATHWAY;hsa03430 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | Hyperaldosteronism;FunDO |
Disease | Cancer;FunDO |
Disease | Mismatch repair cancer syndrome;OMIM |
Disease | Colorectal cancer, hereditary nonpolyposis, type 4;OMIM |
|
External Links |
|
Links to Entrez Gene | 5395 |
Links to all GeneRIF Items | 5395 |
Links to iHOP | 5395 |
|
Sequence Information |
|
Nucleotide Sequence |
>5395 : length: 2589 atggagcgagctgagagctcgagtacagaacctgctaaggccatcaaacctattgatcgg aagtcagtccatcagatttgctctgggcaggtggtactgagtctaagcactgcggtaaag gagttagtagaaaacagtctggatgctggtgccactaatattgatctaaagcttaaggac tatggagtggatcttattgaagtttcagacaatggatgtggggtagaagaagaaaacttc gaaggcttaactctgaaacatcacacatctaagattcaagagtttgccgacctaactcag gttgaaacttttggctttcggggggaagctctgagctcactttgtgcactgagcgatgtc accatttctacctgccacgcatcggcgaaggttggaactcgactgatgtttgatcacaat gggaaaattatccagaaaaccccctacccccgccccagagggaccacagtcagcgtgcag cagttattttccacactacctgtgcgccataaggaatttcaaaggaatattaagaaggag tatgccaaaatggtccaggtcttacatgcatactgtatcatttcagcaggcatccgtgta agttgcaccaatcagcttggacaaggaaaacgacagcctgtggtatgcacaggtggaagc cccagcataaaggaaaatatcggctctgtgtttgggcagaagcagttgcaaagcctcatt ccttttgttcagctgccccctagtgactccgtgtgtgaagagtacggtttgagctgttcc gatgctctgcataatcttttttacatctcaggtttcatttcacaatgcacgcatggagtt ggaaggagttcaacagacagacagtttttctttatcaaccggcggccttgtgacccagca aaggtctgcagactcgtgaatgaggtctaccacatgtataatcgacaccagtatccattt gttgttcttaacatttctgttgattcagaatgcgttgatatcaatgttactccagataaa aggcaaattttgctacaagaggaaaagcttttgttggcagttttaaagacctctttgata ggaatgtttgatagtgatgtcaacaagctaaatgtcagtcagcagccactgctggatgtt gaaggtaacttaataaaaatgcatgcagcggatttggaaaagcccatggtagaaaagcag gatcaatccccttcattaaggactggagaagaaaaaaaagacgtgtccatttccagactg cgagaggccttttctcttcgtcacacaacagagaacaagcctcacagcccaaagactcca gaaccaagaaggagccctctaggacagaaaaggggtatgctgtcttctagcacttcaggt gccatctctgacaaaggcgtcctgagacctcagaaagaggcagtgagttccagtcacgga cccagtgaccctacggacagagcggaggtggagaaggactcggggcacggcagcacttcc gtggattctgaggggttcagcatcccagacacgggcagtcactgcagcagcgagtatgcg gccagctccccaggggacaggggctcgcaggaacatgtggactctcaggagaaagcgcct gaaactgacgactctttttcagatgtggactgccattcaaaccaggaagataccggatgt aaatttcgagttttgcctcagccaactaatctcgcaaccccaaacacaaagcgttttaaa aaagaagaaattctttccagttctgacatttgtcaaaagttagtaaatactcaggacatg tcagcctctcaggttgatgtagctgtgaaaattaataagaaagttgtgcccctggacttt tctatgagttctttagctaaacgaataaagcagttacatcatgaagcacagcaaagtgaa ggggaacagaattacaggaagtttagggcaaagatttgtcctggagaaaatcaagcagcc gaagatgaactaagaaaagagataagtaaaacgatgtttgcagaaatggaaatcattggt cagtttaacctgggatttataataaccaaactgaatgaggatatcttcatagtggaccag catgccacggacgagaagtataacttcgagatgctgcagcagcacaccgtgctccagggg cagaggctcatagcacctcagactctcaacttaactgctgttaatgaagctgttctgata gaaaatctggaaatatttagaaagaatggctttgattttgttatcgatgaaaatgctcca gtcactgaaagggctaaactgatttccttgccaactagtaaaaactggaccttcggaccc caggacgtcgatgaactgatcttcatgctgagcgacagccctggggtcatgtgccggcct tcccgagtcaagcagatgtttgcctccagagcctgccggaagtcggtgatgattgggact gctcttaacacaagcgagatgaagaaactgatcacccacatgggggagatggaccacccc tggaactgtccccatggaaggccaaccatgagacacatcgccaacctgggtgtcatttct cagaactga |
Protein Sequence |
>5395 : length: 862 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKE YAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLI PFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPA KVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLI GMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRL REAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHG PSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAP ETDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVNTQDM SASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAA EDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQG QRLIAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGP QDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHP WNCPHGRPTMRHIANLGVISQN |