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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5395 |
Name | PMS2 |
Synonymous | HNPCC4|PMS2CL|PMSL2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae);PMS2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae) |
Definition | DNA mismatch repair protein PMS2|H_DJ0042M02.9|PMS1 protein homolog 2|mismatch repair endonuclease PMS2 |
Position | 7p22.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
p73alpha(h) + PMS2(h) <==> p73alpha(h):PMS2(h) (binding) | MSH2(h) + PMS2(h) <==> MSH2(h):PMS2(h) (binding) | PMS2(h) --> PMS2(h) (expression). | PCNA(h) + PMS2(h) <==> PCNA(h):PMS2(h) (binding) | PMS2(h) + MSH2(h) <==> PMS2(h):MSH2(h) (binding) | PMS2(h) + MLH1(h) <==> PMS2(h):MLH1(h) (binding) | PMS2(h) + GTBP(h) <==> PMS2(h):GTBP(h) (binding) | PMS2(h) + MLH1(h) + MSH2(h) <==> PMS2(h):MLH1(h):MSH2(h) (binding) | PMS2(h) --> PMS2(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
403 | Phosphoserine. | Swiss-Prot 53.0 | 573 | Phosphothreonine. | Swiss-Prot 53.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr7 |
Promoter: 6014763 - 6016763 | GSE27584 |
chr7 |
Promoter: 6014763 - 6016763 | Agilent_014791_44K |
chr7 |
Promoter: 6014763 - 6016763 | Agilent_014791 |