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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5411 |
Name | PNN |
Synonym | DRS|DRSP|SDK3|memA;pinin, desmosome associated protein;PNN;pinin, desmosome associated protein |
Definition | 140 kDa nuclear and cell adhesion-related phosphoprotein|SR-like protein|desmosome-associated protein|domain-rich serine protein|melanoma metastasis clone A protein|neutrophil protein|nuclear protein SDK3|pinin |
Position | 14q21.1 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 3 PubMed records as below. |
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Evidence Status |
Description |
reviewed | A novel apoptotic pathway induced by the drs tumor suppressor gene. |
potential | Previous work has suggested that Pnn/DRS/memA is a potential tumor suppressor involved in the regulation of cell adhesion and cell migration. |
reviewed | These data lend significant support to the hypothesis that pinin/DRS/memA may act as a tumor suppressor in certain types of cancers. |
| More detail of all 3 literatures about PNN | |
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External Links |
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Links to Entrez Gene | 5411 |
Links to all GeneRIF Items | 5411 |
Links to iHOP | 5411 |
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Sequence Information |
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Nucleotide Sequence |
>5411 : length: 2154 atggcggtcgccgtgagaactttgcaggaacagctggaaaaggccaaagagagtcttaag aacgtggatgagaacattcgcaagctcaccgggcgggatccgaatgacgtgaggcccatc caagccagattgctggccctttctggtcctggtggaggtagaggacgtggtagtttatta ctgaggcgtggattctcagatagtggaggaggacccccagccaaacagagagaccttgaa ggggcagtcagtaggctgggcggggagcgtcggaccagaagagaatcacgccaggaaagc gacccggaggatgatgatgttaaaaagccagcattgcagtcttcagttgtagctacctcc aaagagcgcacacgtagagaccttatccaggatcaaaatatggatgaaaagggaaagcaa aggaaccggcgaatatttggcttgttgatgggtacccttcaaaaatttaaacaagaatcc actgttgctactgaaaggcaaaagcggcgccaggaaattgaacaaaaacttgaagttcag gcagaagaagagagaaagcaggttgaaaatgaaaggagagaactgtttgaagagaggcgt gctaaacagacagaactgcggcttttggaacagaaagttgagcttgcgcagctgcaagaa gaatggaatgaacataatgccaaaataattaaatatataagaactaagacaaagccccat ttgttttatattcctggaagaatgtgtccagctacccaaaaactaatagaagagtcacag agaaaaatgaacgctttatttgaaggtagacgcatcgaatttgcagaacaaataaataaa atggaggctaggcctagaagacaatcaatgaaggaaaaagagcatcaggtggtgcgtaat gaagaacagaaggcggaacaagaagagggtaaggtggctcagcgagaggaagagttggag gagacaggtaatcagcacaatgatgtagaaatagaggaagcaggagaggaagaggaaaag gaaatagcgattgttcatagtgatgcagagaaagaacaggaggaggaagaacaaaaacag gaaatggaggttaagatggaggaggaaactgaggtaagggaaagtgagaagcagcaggat agtcagcctgaagaagttatggatgtgctagagatggttgagaatgtcaaacatgtaatt gctgaccaggaggtaatggaaactaatcgagttgaaagtgtagaaccttcagaaaatgaa gctagcaaagaattggaaccagaaatggaatttgaaattgagccagataaagaatgtaaa tccctttctcctgggaaagagaatgtcagtgctttagacatggaaaaggagtctgaggaa aaagaagaaaaagaatctgagccccaacctgagcctgtggctcaacctcagcctcagtct cagccccagcttcagcttcaatcccagtcccaaccagtactccagtcccagcctccctct cagcctgaggatttgtcattagctgttttacagccaacaccccaagttactcaggagcaa gggcatttactacctgagaggaaggattttcctgtagagtctgtaaaactcactgaggta ccagtagagccagtcttgacagtacatccagagagcaagagcaaaaccaaaactaggagc agaagtagaggtcgagctagaaataaaacaagcaagagtagaagtcgaagcagtagcagt agcagttctagtagcagttcaaccagtagcagcagtggaagtagttccagcagtggaagt agtagcagtcgcagtagttccagtagcagctccagtacaagtggcagcagcagcagagat agtagcagtagcactagtagtagtagtgagagtagaagtcggagtaggggccggggacat aatagagatagaaagcacagaaggagcgtggatcggaagagaagggatacttcaggacta gaaagaagtcacaaatcttcaaaaggtggtagtagtagagatacaaaaggatcaaaggat aagaattcccggtccgacagaaagaggtctatatcagagagtagtcgatcaggcaaaaga tcttcaagaagtgaaagagaccgaaaatcagacaggaaagacaaaaggcgttaa |
Protein Sequence |
>5411 : length: 717 MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR |