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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5411 |
Name | PNN |
Synonymous | DRS|DRSP|SDK3|memA;pinin, desmosome associated protein;PNN;pinin, desmosome associated protein |
Definition | 140 kDa nuclear and cell adhesion-related phosphoprotein|SR-like protein|desmosome-associated protein|domain-rich serine protein|melanoma metastasis clone A protein|neutrophil protein|nuclear protein SDK3|pinin |
Position | 14q21.1 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
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Regulation From TransFac database |
Pinin(h) + PRP4K(h) <==> Pinin(h):PRP4K(h) (binding) | Pinin(h) + PRP4K(h) <==> Pinin(h):PRP4K(h) (binding) | Ku70(h) + Ccte(h) + Pds5A(h) + PPIL1(h) + eIF-3gamma(h) + SAFB1(h) + Wapl(h) + Rad21(h) + SMC-3(h) + SMC1(h) + CAPER-alpha(h) + CNOT3(h) + NCoA-5(h) + SIAHBP1(h) + FBP(h) + HYPA(h) + SKIP(h) + SRm300(h) + SRm160(h) + p54nrb/NonO(h) + rbm25(h) + rbm8A(h) + Pinin(h) + Prp19(h) + cdc5L(h) + Snrp116(h) + Prpf8(h) + Sf3b-4(h) + Sf3b-2(h) + hnRNPM(h) + hnRNP-G(h) <==> Ku70(h):Ccte(h):Pds5A(h):PPIL1(h):eIF-3gamma(h):SAFB1(h):Wapl(h):Rad21(h):SMC-3(h):SMC1(h):CAPER-alpha(h):CNOT3(h):NCoA-5(h):SIAHBP1(h):FBP(h):HYPA(h):SKIP(h):SRm300(h):SRm160(h):p54nrb/NonO(h):rbm25(h):rbm8A(h):Pinin(h):Prp19(h):cdc5L(h):Snrp116(h):Prpf8(h):Sf3b-4(h):Sf3b-2(h):hnRNPM(h):hnRNP-G(h) (binding) | rnps1(h) + Pinin(h) <==> rnps1(h):Pinin(h) (binding) | IKBL(h) + Pinin(h) <==> IKBL(h):Pinin(h) (binding) | Keratin-18(h) + Pinin(h) <==> Keratin-18(h):Pinin(h) (binding) | Keratin-8(h) + Pinin(h) <==> Keratin-8(h):Pinin(h) (binding) | Keratin-19(h) + Pinin(h) <==> Keratin-19(h):Pinin(h) (binding) | Keratin(ca) + Pinin(h) <==> Keratin(ca):Pinin(h) (binding) | Pinin(h) + CAPER-alpha(h) <==> Pinin(h):CAPER-alpha(h) (binding) | PNN(h) --> Pinin(h) (expression). | Sfrs10(h) --> Pinin(h) (binding) | PNN(h) --> Pinin-1(h) (expression). | PNN(h) --> Pinin-2(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
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Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylalanine. | Swiss-Prot 53.0 | 66 | Phosphoserine. | Swiss-Prot 53.0 | 100 | Phosphoserine. | Swiss-Prot 53.0 | 347 | Phosphoserine. | Swiss-Prot 53.0 | 381 | Phosphoserine. | Swiss-Prot 53.0 | 441 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 443 | Phosphoserine. | Swiss-Prot 53.0 | 658 | Phosphoserine. | Swiss-Prot 53.0 | 692 | Phosphoserine. | Swiss-Prot 53.0 | 689 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 442 | Phosphoserine | 16565220;17081983 | Phospho.ELM 6.0 | 346 | Phosphoserine | 16565220;17081983 | Phospho.ELM 6.0 | 65 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 99 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 380 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 412 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 656 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 657 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 691 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
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Chromosome |
Location |
Source |
|---|---|---|
chr14 |
Promoter: 38712651 - 38714651 | GSE27584 |
chr14 |
Promoter: 38712651 - 38714651 | Agilent_014791_44K |