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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 54464 |
Name | XRN1 |
Synonym | SEP1;5'-3' exoribonuclease 1;XRN1;5'-3' exoribonuclease 1 |
Definition | strand-exchange protein 1 homolog |
Position | 3q23 |
Gene Type | protein-coding |
Source | Count: 1; UniProt |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
| . |
| More detail of all 0 literatures about XRN1 | |
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Pathways and Diseases |
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Pathway | mRNA Decay by 5' to 3' Exoribonuclease;PID Reactome;500857 |
Pathway | Metabolism of RNA;Reactome;REACT:21257 |
Pathway | RNA degradation;KEGG PATHWAY;hsa03018 |
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External Links |
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Links to Entrez Gene | 54464 |
Links to all GeneRIF Items | 54464 |
Links to iHOP | 54464 |
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Sequence Information |
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Nucleotide Sequence |
>54464 : length: 5082 atgggagtccccaagttttacagatggatctcagagcggtatccctgtctcagcgaagtg gtgaaagagcatcagattcctgaatttgacaacttgtacctggatatgaatggaattata catcagtgctcccatcctaatgatgatgatgttcactttagaatttcagatgataaaatc tttactgatatttttcactacctggaggtgttgtttcgcattattaaacccaggaaagtg ttctttatggctgtagatggtgtggctcctcgagcaaaaatgaaccagcagcgtgggagg cgttttaggtcagcaaaggaggcagaagacaaaattaaaaaggcaatagagaagggagaa actcttcctacagaggccagatttgattccaactgtatcacaccaggaactgaatttatg gccaggttacatgaacatctgaagtattttgtaaatatgaaaatttccacagacaagtca tggcaaggagttaccatctacttctcaggccatgagactcctggagaaggagagcataaa atcatggaatttatcagatccgagaaagcaaagccagatcatgatccaaacaccagacac tgtctttatggtttagatgctgacttgattatgcttggattaacaagtcatgaggcacat ttttctctcttaagagaagaagttcgatttggtggcaaaaaaacacaacgggtatgtgct ccagaagaaactacatttcaccttctacacttgtctttaatgagagagtatattgactat gagttttcagtattaaaagaaaagatcacatttaaatatgatattgaaaggataatagat gattggattttgatggggtttcttgttggtaatgattttatccctcatctacctcattta catattaatcatgatgcactgcctcttctttatggaacatatgttaccatcctgccagaa cttgggggttatattaatgaaagtgggcacctcaacttacctcgatttgagaaatacctt gtgaaactatcagattttgatcgggagcacttcagtgaagtttttgtggacctaaaatgg tttgaaagcaaagttggtaacaagtacctcaatgaagcagcaggtgtcgcagcagaagaa gccaggaactacaaggaaaagaaaaagttaaagggccaggaaaattctctgtgttggact gctttagacaaaaatgaaggcgaaatgataacttctaaggataatttagaagatgagact gaagatgatgacctatttgaaactgagtttagacaatataaaagaacatattacatgacg aagatgggggttgacgtagtatctgatgactttctggctgatcaagctgcatgttatgtt caggcaatacagtggattttgcactattactatcatggagttcagtcctggagctggtat tatccttatcattatgcacctttcctgtctgatatacacaacatcagtacactcaaaatc cattttgaactaggaaaaccttttaagccatttgaacagcttcttgctgtacttccagca gccagcaaaaatttacttcctgcatgctaccagcatttgatgaccaatgaagactcacca attatagaatattacccacctgattttaaaactgacctaaatgggaaacaacaggaatgg gaagctgtggtgttaatcccttttattgatgagaagcgattattggaagccatggagaca tgtaaccactccctcaaaaaggaagagaggaaaagaaaccaacatagtgagtgcctaatg tgctggtatgatagagacacagagtttatctatccttctccatggccagaaaagttccct gccatagaacgatgttgtacaaggtataaaataatatccttagatgcttggcgtgtagac ataaacaaaaacaaaataaccagaattgaccagaaagcattatatttctgtggatttcct actctgaaacacatcagacacaaattttttttgaagaaaagtggtgttcaagtattccag caaagcagtcgtggagaaaacatgatgttggaaatcttagtggatgcagaatcagatgaa cttaccgtagaaaatgtagcttcatcagtgcttggaaaatctgtctttgttaattggcct caccttgaggaagctagagtcgtggctgtatcagatggagaaactaagttttacttggaa gaacctccaggaacacagaagctttattcaggaagaactgccccaccatctaaagtggtt catcttggagataaagaacaatctaactgggcaaaagaagtacaaggaatttcagaacac tacctgagaagaaaaggaataataataaatgaaacatctgcagttgtgtatgctcagtta ctcacaggtcgtaaatatcaaataaatcaaaatggtgaagttcgtctagagaaacagtgg tcaaaacaagttgttccttttgtttatcaaactattgtcaaggacatccgagctttcgac tcccgtttctccaatatcaaaacattggatgatttgtttcctctgagaagtatggtcttt atgctgggaactccctattatggctgcactggagaagttcaggattcaggtgatgtgatt acagaaggtaggattcgtgtgattttcagcattccatgtgaacccaatcttgatgcttta atacagaaccagcataaatattctataaagtacaacccaggatatgtgttggccagtcgc cttggagtgagtggataccttgtttcaaggtttacaggaagtatttttattggaagagga tctaggagaaaccctcatggagaccataaagcaaatgtgggtttaaatctcaaattcaac aagaaaaatgaggaggtacctggatatactaagaaagttggaagtgaatggatgtattca tctgcagcagaacaacttctggcagagtacttagagagagctccagaactatttagttat atagccaaaaatagccaagaggatgtgttctatgaagatgacatttggcctggagaaaat gagaatggtgctgaaaaagttcaagaaattattacttggctaaaaggacatcctgtcagt actttatctcgttcttcttgtgatttacaaattctggatgcagctattgttgagaaaatt gaggaagaagtcgaaaagtgcaagcaaagaaagaataataagaaggtgcgagtaacagtg aaaccccatttgctatacagacctttagaacagcaacatggagtcattcctgatcgggat gcagaattttgtctttttgaccgtgttgtaaatgtgagagaaaacttctcagttccagtt ggccttcgaggcaccatcataggaataaaaggagctaatagagaagccgatgtactattt gaagtattatttgatgaagaatttcctggagggttaacaataagatgctcacctggtaga ggttatcgactgccaacaagtgccttggtgaacctttctcatgggagtcgctctgaaact ggaaatcagaagttgacagccatcgtaaaaccacaaccagctgtacatcaacatagctca agttcatcagtttcctctgggcatttgggagccctcaaccattcccctcaatcacttttt gttcctactcaagtacctactaaagatgatgatgaattctgcaacatttggcagtcctta cagggatctggaaagatgcaatactttcagccaactatacaagagaagggtgcagttcta cctcaagaaataagccaagtaaatcaacatcataaatctggctttaatgacaacagtgtt aaatatcagcaaagaaaacatgaccctcacagaaaatttaaagaagagtgtaagagtcct aaagctgagtgttggtcccaaaaaatgtccaataagcagcctaactctggaattgagaac tttttagcatctttgaatatctccaaagaaaatgaagtacagtcatctcatcatggggag cctccaagtgaagagcatttgtcaccacagtcatttgccatgggaacacggatgcttaaa gaaattctaaaaattgatggctctaacactgtggaccataagaatgaaatcaaacagatt gctaatgaaatccctgtttcctctaacagaagagatgaatatggattaccctctcagcct aaacaaaataagaaattagcatcttatatgaacaagcctcacagtgctaatgagtaccat aatgttcagtctatggacaatatgtgttggcctgcccccagccagatccctcctgtatcc acaccagtaactgaactttctcgaatttgttcccttgttggaatgccacaacctgatttc tcctttcttaggatgccacagacaatgaccgtttgccaagtaaaattatctaatggctta ctggtacatgggccacagtgccactctgaaaatgaagccaaagagaaagctgcacttttt gctttacaacagttgggctccttaggcatgaatttccctttgccttcacaagtatttgca aattatccttcagctgtaccacctggaaccattcctccagcctttcccccacctactgct aatataatgccttcgtcgtctcatctctttggctcaatgccatggggaccatcggtgcca gttcctgggaagcccttccatcatactttatattctgggaccatgcccatggctggggga ataccagggggtgtgcacaatcagtttatacctctgcaggttactaaaaaaagggttgca aacaaaaagaactttgagaataaggaagcccagagttctcaagccactccagttcagact agccagccagattcttccaacattgtcaaagtaagtccacgggagagctcatcagcttct ttgaagtcctctccgattgctcaacctgcatcttcttttcaagttgaaactgcctctcaa ggccatagtatatctcaccataagtcaacaccaatctcttcttcaagaagaaaatcaaga aaactggctgttaattttggtgtttctaaaccttctgagtaa |
Protein Sequence |
>54464 : length: 1693 MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKI FTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGE TLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHK IMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCA PEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHL HINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKW FESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDET EDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWY YPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSP IIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLM CWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFP TLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWP HLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEH YLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFD SRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDAL IQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFN KKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGEN ENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTV KPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLF EVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSS SSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVL PQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIEN FLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQI ANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVS TPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALF ALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVP VPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQT SQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSR KLAVNFGVSKPSE |