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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5782 |
Name | PTPN12 |
Synonym | PTP-PEST|PTPG1;protein tyrosine phosphatase, non-receptor type 12;PTPN12;protein tyrosine phosphatase, non-receptor type 12 |
Definition | protein-tyrosine phosphatase G1|tyrosine-protein phosphatase non-receptor type 12 |
Position | 7q11.23 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "Using a genetic screen, study identifies the PTPN12 tyrosine phosphatase as a tumor suppressor in triple-negative breast cancer (TNBC)." |
| More detail of all 1 literatures about PTPN12 | |
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Pathways and Diseases |
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Pathway | Integrin signalling pathway;PANTHER;P00034 |
Disease | Eye disease;FunDO |
Disease | Graves ophthalmology Graves' disease;GAD |
Disease | Colon cancer;OMIM |
Disease | VISION;GAD |
Disease | Prostate cancer;FunDO |
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External Links |
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Links to Entrez Gene | 5782 |
Links to all GeneRIF Items | 5782 |
Links to iHOP | 5782 |
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Sequence Information |
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Nucleotide Sequence |
>5782 : length: 1986 atgatatgggagtataatgttgtgatcattgtaatggcctgccgagaatttgagatggga aggaaaaaatgtgagcgctattggcctttgtatggagaagaccccataacgtttgcacca tttaaaatttcttgtgaggatgaacaagcaagaacagactacttcatcaggacactctta cttgaatttcaaaatgaatctcgtaggctgtatcagtttcattatgtgaactggccagac catgatgttccttcatcatttgattctattctggacatgataagcttaatgaggaaatat caagaacatgaagatgttcctatttgtattcattgcagtgcaggctgtggaagaacaggt gccatttgtgccatagattatacgtggaatttactaaaagctgggaaaataccagaggaa tttaatgtatttaatttaatacaagaaatgagaacacaaaggcattctgcagtacaaaca aaggagcaatatgaacttgttcatagagctattgcccaactgtttgaaaaacagctacaa ctatatgaaattcatggagctcagaaaattgctgatggagtgaatgaaattaacactgaa aacatggtcagctccatagagcctgaaaaacaagattctcctcctccaaaaccaccaagg acccgcagttgccttgttgaaggggatgctaaagaagaaatactgcagccaccggaacct catccagtgccacccatcttgacaccttctcccccttcagcttttccaacagtcactact gtgtggcaggacaatgatagataccatccaaagccagtgttgcatatggtttcatcagaa caacattcagcagacctcaacagaaactatagtaaatcaacagaacttccagggaaaaat gaatcaacaattgaacagatagataaaaaattggaacgaaatttaagttttgagattaag aaggtccctctccaagagggaccaaaaagttttgatgggaacacacttttgaatagggga catgcaattaaaattaaatctgcttcaccttgtatagctgataaaatctctaagccacag gaattaagttcagatctaaatgtcggtgatacttcccagaattcttgtgtggactgcagt gtaacacaatcaaacaaagtttcagttactccaccagaagaatcccagaattcagacaca cctccaaggccagaccgcttgcctcttgatgagaaaggacatgtaacgtggtcatttcat ggacctgaaaatgccatacccatacctgatttatctgaaggcaattcctcagatatcaac tatcaaactaggaaaactgtgagtttaacaccaagtcctacaacacaagttgaaacacct gatcttgtggatcatgataacacttcaccactcttcagaacacccctcagttttactaat ccacttcactctgatgactcagactcagatgaaagaaactctgatggtgctgtgacccag aataaaactaatatttcaacagcaagtgccacagtttctgctgccactagtactgaaagc atttctactaggaaagtattgccaatgtccattgctagacataatatagcaggaacaaca cattcaggtgctgaaaaagatgttgatgttagtgaagattcacctcctcccctacctgaa agaactcctgaatcgtttgtgttagcaagtgaacataatacacctgtaagatcggaatgg agtgaacttcaaagtcaggaacgatctgaacaaaaaaagtctgaaggcttgataacctct gaaaatgagaaatgtgatcatccagcgggaggtattcactatgaaatgtgcatagaatgt ccacctactttcagtgacaagagagaacaaatatcagaaaatccaacagaagccacagat attggttttggtaatcgatgtggaaaacccaaaggaccaagagatccaccttcagaatgg acatga |
Protein Sequence |
>5782 : length: 661 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW T |