Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

5782

Name

PTPN12

Synonym

PTP-PEST|PTPG1;protein tyrosine phosphatase, non-receptor type 12;PTPN12;protein tyrosine phosphatase, non-receptor type 12

Definition

protein-tyrosine phosphatase G1|tyrosine-protein phosphatase non-receptor type 12

Position

7q11.23

Gene Type

protein-coding

Source

Count: 2; TAG,Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

"Using a genetic screen, study identifies the PTPN12 tyrosine phosphatase as a tumor suppressor in triple-negative breast cancer (TNBC)."
More detail of all 1 literatures about PTPN12

Pathways and Diseases

Pathway

Integrin signalling pathway;PANTHER;P00034

Disease

Eye disease;FunDO

Disease

Graves ophthalmology Graves' disease;GAD

Disease

Colon cancer;OMIM

Disease

VISION;GAD

Disease

Prostate cancer;FunDO

External Links

Links to Entrez Gene

5782

Links to all GeneRIF Items

5782

Links to iHOP

5782

Sequence Information

Nucleotide Sequence

>5782 : length: 1986
atgatatgggagtataatgttgtgatcattgtaatggcctgccgagaatttgagatggga
aggaaaaaatgtgagcgctattggcctttgtatggagaagaccccataacgtttgcacca
tttaaaatttcttgtgaggatgaacaagcaagaacagactacttcatcaggacactctta
cttgaatttcaaaatgaatctcgtaggctgtatcagtttcattatgtgaactggccagac
catgatgttccttcatcatttgattctattctggacatgataagcttaatgaggaaatat
caagaacatgaagatgttcctatttgtattcattgcagtgcaggctgtggaagaacaggt
gccatttgtgccatagattatacgtggaatttactaaaagctgggaaaataccagaggaa
tttaatgtatttaatttaatacaagaaatgagaacacaaaggcattctgcagtacaaaca
aaggagcaatatgaacttgttcatagagctattgcccaactgtttgaaaaacagctacaa
ctatatgaaattcatggagctcagaaaattgctgatggagtgaatgaaattaacactgaa
aacatggtcagctccatagagcctgaaaaacaagattctcctcctccaaaaccaccaagg
acccgcagttgccttgttgaaggggatgctaaagaagaaatactgcagccaccggaacct
catccagtgccacccatcttgacaccttctcccccttcagcttttccaacagtcactact
gtgtggcaggacaatgatagataccatccaaagccagtgttgcatatggtttcatcagaa
caacattcagcagacctcaacagaaactatagtaaatcaacagaacttccagggaaaaat
gaatcaacaattgaacagatagataaaaaattggaacgaaatttaagttttgagattaag
aaggtccctctccaagagggaccaaaaagttttgatgggaacacacttttgaatagggga
catgcaattaaaattaaatctgcttcaccttgtatagctgataaaatctctaagccacag
gaattaagttcagatctaaatgtcggtgatacttcccagaattcttgtgtggactgcagt
gtaacacaatcaaacaaagtttcagttactccaccagaagaatcccagaattcagacaca
cctccaaggccagaccgcttgcctcttgatgagaaaggacatgtaacgtggtcatttcat
ggacctgaaaatgccatacccatacctgatttatctgaaggcaattcctcagatatcaac
tatcaaactaggaaaactgtgagtttaacaccaagtcctacaacacaagttgaaacacct
gatcttgtggatcatgataacacttcaccactcttcagaacacccctcagttttactaat
ccacttcactctgatgactcagactcagatgaaagaaactctgatggtgctgtgacccag
aataaaactaatatttcaacagcaagtgccacagtttctgctgccactagtactgaaagc
atttctactaggaaagtattgccaatgtccattgctagacataatatagcaggaacaaca
cattcaggtgctgaaaaagatgttgatgttagtgaagattcacctcctcccctacctgaa
agaactcctgaatcgtttgtgttagcaagtgaacataatacacctgtaagatcggaatgg
agtgaacttcaaagtcaggaacgatctgaacaaaaaaagtctgaaggcttgataacctct
gaaaatgagaaatgtgatcatccagcgggaggtattcactatgaaatgtgcatagaatgt
ccacctactttcagtgacaagagagaacaaatatcagaaaatccaacagaagccacagat
attggttttggtaatcgatgtggaaaacccaaaggaccaagagatccaccttcagaatgg
acatga

Protein Sequence

>5782 : length: 661
MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL
LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG
AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ
LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP
HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN
ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ
ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH
GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN
PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT
HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS
ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW
T



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