|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6196 |
Name | RPS6KA2 |
Synonym | HU-2|MAPKAPK1C|RSK|RSK3|S6K-alpha|S6K-alpha2|p90-RSK3|pp90RSK3;ribosomal protein S6 kinase, 90kDa, polypeptide 2;RPS6KA2;ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
Definition | 90 kDa ribosomal protein S6 kinase 2|MAP kinase-activated protein kinase 1c|MAPK-activated protein kinase 1c|MAPKAP kinase 1c|MAPKAPK-1c|RSK-3|S6K-alpha-2|p90-RSK 2|p90RSK2|ribosomal S6 kinase 3|ribosomal protein S6 kinase alpha 2|ribosomal protein S6 kin |
Position | 6q27 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 1 PubMed records as below. |
|
Evidence Status |
Description |
potential | "RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer." |
| More detail of all 1 literatures about RPS6KA2 | |
|
Pathways and Diseases |
|
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade;PANTHER;P00032 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Ras Pathway;PANTHER;P04393 |
Disease | Cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 6196 |
Links to all GeneRIF Items | 6196 |
Links to iHOP | 6196 |
|
Sequence Information |
|
Nucleotide Sequence |
>6196 : length: 2226 atgccaatcgcacagttgctggaactatggaaaaagatcgaggtggagcctatggaaata gagaccacagaggaggatctcaacctggatgtggagcccaccacagaagacactgcagaa gaagaagaaggcgtcgtgaaggagatagacatcagccatcatgtgaaggagggctttgag aaggcagatccttcccagtttgagctgctgaaggttttaggacaaggatcctatggaaag gtgttcctggtgaggaaggtgaaggggtccgacgctgggcagctctacgccatgaaggtc cttaagaaagccaccctaaaagttcgggaccgagtgagatcgaagatggagagagacatc ttggcagaagtgaatcaccccttcattgtgaagcttcattatgcctttcagacggaagga aagctctacctgatcctggacttcctgcggggaggggacctcttcacccggctctccaaa gaggtcatgttcacggaggaggatgtcaagttctacctggctgagctggccttggcttta gaccatctccacagcctggggatcatctacagagatctgaagcctgagaacatcctcctg gatgaagaggggcacattaagatcacagatttcggcctgagtaaggaggccattgaccac gacaagagagcgtactccttctgcgggacgatcgagtacatggcgcccgaggtggtgaac cggcgaggacacacgcagagtgccgactggtggtccttcggcgtgctcatgtttgagatg ctcacggggtccctgccgttccaggggaaggacaggaaggagaccatggctctcatcctc aaagccaagctggggatgccgcagttcctcagtggggaggcacagagtttgctgcgagct ctcttcaaacggaacccctgcaaccggctgggtgctggcattgacggagtggaggaaatt aagcgccatcccttctttgtgaccatagactggaacacgctgtaccggaaggagatcaag ccaccgttcaaaccagcagtgggcaggcctgaggacaccttccactttgaccccgagttc acagcgcggacgcccacagactctcctggcgtccccccgagtgcaaacgctcatcacctg tttagaggattcagctttgtggcctcaagcctgatccaggagccctcacagcaagatctg cacaaagtcccagttcacccaatcgtgcagcagttacacgggaacaacatccacttcacc gatggctacgagatcaaggaggacatcggggtgggctcctactcagtgtgcaagcgatgt gtgcataaagccacagacaccgagtatgccgtgaagatcattgataagagcaagagagac ccctcggaagagattgagatcctcctgcggtacggccagcacccgaacatcatcaccctc aaggatgtctatgatgatggcaagtttgtgtacctggtaatggagctgatgcgtggtggg gagctcctggaccgcatcctccggcagagatacttctcggagcgcgaagccagtgacgtc ctgtgcaccatcaccaagaccatggactacctccattcccagggggttgttcatcgagac ctgaagccgagtaacatcctgtacagggatgagtcggggagcccagaatccatccgagtc tgcgacttcggctttgccaagcagctgcgcgcggggaacgggctgctcatgacaccctgc tacacggccaatttcgtggccccggaggtcctgaagcgtcaaggctatgatgcggcgtgt gacatctggagtttggggatcctgttgtacaccatgctggcaggatttaccccttttgca aatgggccagacgatacccctgaggagattctggcgcggatcggcagtgggaagtatgcc ctttctgggggaaactgggactcgatatctgacgcagctaaagacgtcgtgtccaagatg ctccacgtggaccctcatcagcgcctgacggcgatgcaagtgctcaaacacccgtgggtg gtcaacagagagtacctgtccccaaaccagctcagccgacaggacgtgcacctggtgaag ggcgcgatggccgccacctactttgctctaaacagaacacctcaggccccgcggctggag cccgtgctgtcatccaacctggctcagcgcagaggcatgaagagactcacgtccacgcgg ctgtag |
Protein Sequence |
>6196 : length: 741 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVEPTTEDTAEEEEGVVKEIDISHHVKEGFE KADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDI LAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAL DHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVN RRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRA LFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEF TARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFT DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITL KDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRD LKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAAC DIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKM LHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLE PVLSSNLAQRRGMKRLTSTRL |