Basic Information
Gene ID	6196
Name	RPS6KA2
Synonymous	HU-2\|MAPKAPK1C\|RSK\|RSK3\|S6K-alpha\|S6K-alpha2\|p90-RSK3\|pp90RSK3;ribosomal protein S6 kinase, 90kDa, polypeptide 2;RPS6KA2;ribosomal protein S6 kinase, 90kDa, polypeptide 2
Definition	90 kDa ribosomal protein S6 kinase 2\|MAP kinase-activated protein kinase 1c\|MAPK-activated protein kinase 1c\|MAPKAP kinase 1c\|MAPKAPK-1c\|RSK-3\|S6K-alpha-2\|p90-RSK 2\|p90RSK2\|ribosomal S6 kinase 3\|ribosomal protein S6 kinase alpha 2\|ribosomal protein S6 kin
Position	6q27
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database
ERK1(h) + RSK3(h) <==> ERK1(h):RSK3(h) (binding)
ERK2(h) + RSK3(h) <==> ERK2(h):RSK3(h) (binding)
ERK1(mo) + RSK3(h) <==> ERK1(mo):RSK3(h) (binding)
ERK1(mo){p} + RSK3(h) <==> ERK1(mo){p}:RSK3(h) (binding)
ERK2(mo) + RSK3(h) <==> ERK2(mo):RSK3(h) (binding)
ERK2(mo){p} + RSK3(h) <==> ERK2(mo){p}:RSK3(h) (binding)
RSK3(h) + ATP --ERK1(h)--> RSK3(h){p} + ADP (phosphorylation)
RSK3(h) + 2 ATP --> RSK3(h){pS381}{pT573} + 2 ADP (phosphorylation)
RSK3(h) + ATP --> RSK3(h){pS381} + ADP (phosphorylation)
RPS6KA2(h) --> RSK3(h) (expression).
RPS6KA2(h) --> RSK3(h) (expression).

Location (AA)	PTM type	Database
218	Phosphoserine.	Swiss-Prot 53.0
356	Phosphothreonine (By similarity).	Swiss-Prot 53.0
360	Phosphoserine (By similarity).	Swiss-Prot 53.0
377	Phosphoserine (by autocatalysis) (Bysimilarity).	Swiss-Prot 53.0
570	Phosphothreonine (By similarity).	Swiss-Prot 53.0
730	Phosphoserine (By similarity).	Swiss-Prot 53.0