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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 701 |
Name | BUB1B |
Synonym | BUB1beta|BUBR1|Bub1A|MAD3L|SSK1|hBUBR1;budding uninhibited by benzimidazoles 1 homolog beta (yeast);BUB1B;budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
Definition | MAD3/BUB1-related protein kinase|mitotic checkpoint kinase MAD3L|mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
Position | 15q15 |
Gene Type | protein-coding |
Source | Count: 1; UniProt |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
| . |
| More detail of all 0 literatures about BUB1B | |
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Pathways and Diseases |
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Pathway | APC/C:Cdc20 mediated degradation of mitotic proteins;PID Reactome;500396 |
Pathway | APC-Cdc20 mediated degradation of Nek2A;Reactome;REACT:8017 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Cdc20:Phospho-APC/C mediated degradation of Cyclin A;Reactome;REACT:6850 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | PLK1 signaling events;PID Curated;200087 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | Inactivation of APC/C via direct inhibition of the APC/C complex;PID Reactome;500328 |
Pathway | DNA Replication;Reactome;REACT:383 |
Disease | Premature chromatid separation trait;OMIM |
Disease | Cancer;FunDO |
Disease | Colorectal cancer;OMIM |
Disease | Mosaic variegated aneuploidy syndrome;OMIM |
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External Links |
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Links to Entrez Gene | 701 |
Links to all GeneRIF Items | 701 |
Links to iHOP | 701 |
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Sequence Information |
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Nucleotide Sequence |
>701 : length: 3153 atggcggcggtgaagaaggaagggggtgctctgagtgaagccatgtccctggagggagat gaatgggaactgagtaaagaaaatgtacaacctttaaggcaagggcggatcatgtccacg cttcagggagcactggcacaagaatctgcctgtaacaatactcttcagcagcagaaacgg gcatttgaatatgaaattcgattttacactggaaatgaccctctggatgtttgggatagg tatatcagctggacagagcagaactatcctcaaggtgggaaggagagtaatatgtcaacg ttattagaaagagctgtagaagcactacaaggagaaaaacgatattatagtgatcctcga tttctcaatctctggcttaaattagggcgtttatgcaatgagcctttggatatgtacagt tacttgcacaaccaagggattggtgtttcacttgctcagttctatatctcatgggcagaa gaatatgaagctagagaaaactttaggaaagcagatgcgatatttcaggaagggattcaa cagaaggctgaaccactagaaagactacagtcccagcaccgacaattccaagctcgagtg tctcggcaaactctgttggcacttgagaaagaagaagaggaggaagtttttgagtcttct gtaccacaacgaagcacactagctgaactaaagagcaaagggaaaaagacagcaagagct ccaatcatccgtgtaggaggtgctctcaaggctccaagccagaacagaggactccaaaat ccatttcctcaacagatgcaaaataatagtagaattactgtttttgatgaaaatgctgat gaggcttctacagcagagttgtctaagcctacagtccagccatggatagcaccccccatg cccagggccaaagagaatgagctgcaagcaggcccttggaacacaggcaggtccttggaa cacaggcctcgtggcaatacagcttcactgatagctgtacccgctgtgcttcccagtttc actccatatgtggaagagactgcacaacagccagttatgacaccatgtaaaattgaacct agtataaaccacatcctaagcaccagaaagcctggaaaggaagaaggagatcctctacaa agggttcagagccatcagcaagcgtctgaggagaagaaagagaagatgatgtattgtaag gagaagatttatgcaggagtaggggaattctcctttgaagaaattcgggctgaagttttc cggaagaaattaaaagagcaaagggaagccgagctattgaccagtgcagagaagagagca gaaatgcagaaacagattgaagagatggagaagaagctaaaagaaatccaaactactcag caagaaagaacaggtgatcagcaagaagagacgatgcctacaaaggagacaactaaactg caaattgcttccgagtctcagaaaataccaggaatgactctatccagttctgtttgtcaa gtaaactgttgtgccagagaaacttcacttgcggagaacatttggcaggaacaacctcat tctaaaggtcccagtgtacctttctccatttttgatgagtttcttctttcagaaaagaag aataaaagtcctcctgcagatcccccacgagttttagctcaacgaagaccccttgcagtt ctcaaaacctcagaaagcatcacctcaaatgaagatgtgtctccagatgtttgtgatgaa tttacaggaattgaacccttgagcgaggatgccattatcacaggcttcagaaatgtaaca atttgtcctaacccagaagacacttgtgactttgccagagcagctcgttttgtatccact ccttttcatgagataatgtccttgaaggatctcccttctgatcctgagagactgttaccg gaagaagatctagatgtaaagacctctgaggaccagcagacagcttgtggcactatctac agtcagactctcagcatcaagaagctgagcccaattattgaagacagtcgtgaagccaca cactcctctggcttctctggttcttctgcctcggttgcaagcacctcctccatcaaatgt cttcaaattcctgagaaactagaacttactaatgagacttcagaaaaccctactcagtca ccatggtgttcacagtatcgcagacagctactgaagtccctaccagagttaagtgcctct gcagagttgtgtatagaagacagaccaatgcctaagttggaaattgagaaggaaattgaa ttaggtaatgaggattactgcattaaacgagaatacctaatatgtgaagattacaagtta ttctgggtggcgccaagaaactctgcagaattaacagtaataaaggtatcttctcaacct gtcccatgggacttttatatcaacctcaagttaaaggaacgtttaaatgaagattttgat catttttgcagctgttatcaatatcaagatggctgtattgtttggcaccaatatataaac tgcttcacccttcaggatcttctccaacacagtgaatatattacccatgaaataacagtg ttgattatttataaccttttgacaatagtggagatgctacacaaagcagaaatagtccat ggtgacttgagtccaaggtgtctgattctcagaaacagaatccacgatccctatgattgt aacaagaacaatcaagctttgaagatagtggacttttcctacagtgttgaccttagggtg cagctggatgtttttaccctcagcggctttcggactgtacagatcctggaaggacaaaag atcctggctaactgttcttctccctaccaggtagacctgtttggtatagcagatttagca catttactattgttcaaggaacacctacaggtcttctgggatgggtccttctggaaactt agccaaaatatttctgagctaaaagatggtgaattgtggaataaattctttgtgcggatt ctgaatgccaatgatgaggccacagtgtctgttcttggggagcttgcagcagaaatgaat ggggtttttgacactacattccaaagtcacctgaacaaagccttatggaaggtagggaag ttaactagtcctggggctttgctctttcagtga |
Protein Sequence |
>701 : length: 1050 MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKR AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPR FLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGIQ QKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFESSVPQRSTLAELKSKGKKTARA PIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIAPPM PRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETAQQPVMTPCKIEP SINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVF RKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTKETTKL QIASESQKIPGMTLSSSVCQVNCCARETSLAENIWQEQPHSKGPSVPFSIFDEFLLSEKK NKSPPADPPRVLAQRRPLAVLKTSESITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVT ICPNPEDTCDFARAARFVSTPFHEIMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIY SQTLSIKKLSPIIEDSREATHSSGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQS PWCSQYRRQLLKSLPELSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKL FWVAPRNSAELTVIKVSSQPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYIN CFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDC NKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLA HLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMN GVFDTTFQSHLNKALWKVGKLTSPGALLFQ |