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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 701 |
Name | BUB1B |
Synonymous | BUB1beta|BUBR1|Bub1A|MAD3L|SSK1|hBUBR1;budding uninhibited by benzimidazoles 1 homolog beta (yeast);BUB1B;budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
Definition | MAD3/BUB1-related protein kinase|mitotic checkpoint kinase MAD3L|mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
Position | 15q15 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
Bub3(h) + BubR1(h) <==> Bub3(h):BubR1(h) (binding) | CENP-E(h) + BubR1(h) <==> CENP-E(h):BubR1(h) (binding) | Cdc20(h) + BubR1(h) <==> Cdc20(h):BubR1(h) (binding) | BubR1(h) + gamma-synuclein(m.s.) <==> BubR1(h):gamma-synuclein(m.s.) (binding) | BubR1(h) + gamma-synuclein(h) <==> BubR1(h):gamma-synuclein(h) (binding) | APC7(h) + Cdc20(h) + MAD2(h) + Bub3(h) + BubR1(h) <==> APC7(h):Cdc20(h):MAD2(h):Bub3(h):BubR1(h) (binding) | Cdc20(h) + MAD2(h) + Bub3(h) + BubR1(h) <==> Cdc20(h):MAD2(h):Bub3(h):BubR1(h) (binding) | plk1(h) + BubR1(h) <==> plk1(h):BubR1(h) (binding) | cyclosome(h) + Cdc20(h) + MAD2(h) + BubR1(h) <==> cyclosome(h):Cdc20(h):MAD2(h):BubR1(h) (binding) | BubR1(h) + Cdc20(h) <==> BubR1(h):Cdc20(h) (binding) | plk1(m.s.) + BubR1(h) <==> plk1(m.s.):BubR1(h) (binding) | BubR1(h) + APC7(h) <==> BubR1(h):APC7(h) (binding) | BubR1(h) + ATP --plk1(h)--> BubR1(h){pS676} + ADP (phosphorylation) | BubR1(h) + n ATP --plk1(h)--> BubR1(h){p}n + n ADP (phosphorylation) | BUB1B(h) --> BubR1(h) (expression). | cyclosome(h):Cdc20(h){ub}n:MAD2(h):BubR1(h) <==> cyclosome(h):Cdc20(h){ub}n + MAD2(h) + BubR1(h) (dissociation) | BubR1(h) + ATP --plk1(h)--> BubR1(h){p} + ADP (phosphorylation) | BubR1(h) + ATP --Cdk1(m.s.)--> BubR1(h){p} + ADP (phosphorylation) | BUB1B(h) --> BubR1(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
There is no record for BUB1B |
Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr15 |
Promoter: 38239030 - 38241030 | Agilent_014791 |
chr15 |
Promoter: 38239030 - 38241030 | GSE27584 |
chr15 |
Promoter: 38239030 - 38241030 | Agilent_014791_44K |
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