Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

701

Name

BUB1B

Synonymous

BUB1beta|BUBR1|Bub1A|MAD3L|SSK1|hBUBR1;budding uninhibited by benzimidazoles 1 homolog beta (yeast);BUB1B;budding uninhibited by benzimidazoles 1 homolog beta (yeast)

Definition

MAD3/BUB1-related protein kinase|mitotic checkpoint kinase MAD3L|mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Position

15q15

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

Bub3(h) + BubR1(h) <==> Bub3(h):BubR1(h) (binding)
CENP-E(h) + BubR1(h) <==> CENP-E(h):BubR1(h) (binding)
Cdc20(h) + BubR1(h) <==> Cdc20(h):BubR1(h) (binding)
BubR1(h) + gamma-synuclein(m.s.) <==> BubR1(h):gamma-synuclein(m.s.) (binding)
BubR1(h) + gamma-synuclein(h) <==> BubR1(h):gamma-synuclein(h) (binding)
APC7(h) + Cdc20(h) + MAD2(h) + Bub3(h) + BubR1(h) <==> APC7(h):Cdc20(h):MAD2(h):Bub3(h):BubR1(h) (binding)
Cdc20(h) + MAD2(h) + Bub3(h) + BubR1(h) <==> Cdc20(h):MAD2(h):Bub3(h):BubR1(h) (binding)
plk1(h) + BubR1(h) <==> plk1(h):BubR1(h) (binding)
cyclosome(h) + Cdc20(h) + MAD2(h) + BubR1(h) <==> cyclosome(h):Cdc20(h):MAD2(h):BubR1(h) (binding)
BubR1(h) + Cdc20(h) <==> BubR1(h):Cdc20(h) (binding)
plk1(m.s.) + BubR1(h) <==> plk1(m.s.):BubR1(h) (binding)
BubR1(h) + APC7(h) <==> BubR1(h):APC7(h) (binding)
BubR1(h) + ATP --plk1(h)--> BubR1(h){pS676} + ADP (phosphorylation)
BubR1(h) + n ATP --plk1(h)--> BubR1(h){p}n + n ADP (phosphorylation)
BUB1B(h) --> BubR1(h) (expression).
cyclosome(h):Cdc20(h){ub}n:MAD2(h):BubR1(h) <==> cyclosome(h):Cdc20(h){ub}n + MAD2(h) + BubR1(h) (dissociation)
BubR1(h) + ATP --plk1(h)--> BubR1(h){p} + ADP (phosphorylation)
BubR1(h) + ATP --Cdk1(m.s.)--> BubR1(h){p} + ADP (phosphorylation)
BUB1B(h) --> BubR1(h) (expression).

Post Transcriptional Modification From dbPTM

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There is no record for BUB1B

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr15

Promoter: 38239030 - 38241030Agilent_014791

chr15

Promoter: 38239030 - 38241030GSE27584

chr15

Promoter: 38239030 - 38241030Agilent_014791_44K


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