Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

7704

Name

ZBTB16

Synonym

PLZF|ZNF145;zinc finger and BTB domain containing 16;ZBTB16;zinc finger and BTB domain containing 16

Definition

zinc finger and BTB domain-containing protein 16|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)|zinc finger protein PLZF

Position

11q23.1

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

Increased expression of the tumor suppressor PLZF in malignant melanomas is associated with long-term patient survival.
More detail of all 1 literatures about ZBTB16

Pathways and Diseases

Pathway

map kinase inactivation of smrt corepressor;PID BioCarta;100032

Pathway

Pathways in cancer;KEGG PATHWAY;hsa05200

Pathway

Acute myeloid leukemia;KEGG PATHWAY;hsa05221

Disease

Cancers;KEGG DISEASE

Disease

PSYCH;GAD

Disease

Acute myeloid leukemia (AML);KEGG DISEASE;H00003

Disease

Cancers of haematopoietic and lymphoid tissues;KEGG DISEASE

Disease

Conduct disorder (interaction);NHGRI

Disease

Conduct disorder (interaction);GAD

Disease

Leukemia, acute promyelocytic, PL2F/RARA type;OMIM

Disease

Skeletal defects, genital hypoplasia, and mental retardation;OMIM

External Links

Links to Entrez Gene

7704

Links to all GeneRIF Items

7704

Links to iHOP

7704

Sequence Information

Nucleotide Sequence

>7704 : length: 2022
atggatctgacaaaaatgggcatgatccagctgcagaaccctagccaccccacggggcta
ctgtgcaaggccaaccagatgcggctggccgggactttgtgcgatgtggtcatcatggtg
gacagccaggagttccacgcccaccggacggtgctggcctgcaccagcaagatgtttgag
atcctcttccaccgcaatagtcaacactatactttggacttcctctcgccaaagaccttc
cagcagattctggagtatgcatatacagccacgctgcaagccaaggcggaggacctggat
gacctgctgtatgcggccgagatcctggagatcgagtacctggaggaacagtgcctgaag
atgctggagaccatccaggcctcagacgacaatgacacggaggccaccatggccgatggc
ggggccgaggaagaagaggaccgcaaggctcggtacctcaagaacatcttcatctcgaag
cattccagcgaggagagtgggtatgccagtgtggctggacagagcctccctgggcccatg
gtggaccagagcccttcagtctccacttcatttggtctttcagccatgagtcccaccaag
gctgcagtggacagtttgatgaccataggacagtctctcctgcagggaactcttcagcca
cctgcagggcccgaggagccaactctggctgggggtgggcggcaccctggggtggctgag
gtgaagacggagatgatgcaggtggatgaggtgcccagccaggacagccctggggcagcc
gagtccagcatctcaggagggatgggggacaaggttgaggaaagaggcaaagaggggcct
gggaccccgactcgaagcagcgtcatcaccagtgctagggagctacactatgggcgagag
gagagtgccgagcaggtgccacccccagctgaggctggccaggcccccactggccgacct
gagcacccagcacccccgcctgagaagcatctgggcatctactccgtgttgcccaaccac
aaggctgacgctgtattgagcatgccgtcttccgtgacctctggcctccacgtgcagcct
gccctggctgtctccatggacttcagcacctatggggggctgctgccccagggcttcatc
cagagggagctgttcagcaagctgggggagctggctgtgggcatgaagtcagagagccgg
accatcggagagcagtgcagcgtgtgtggggtcgagcttcctgataacgaggctgtggag
cagcacaggaagctgcacagtgggatgaagacgtacgggtgcgagctctgcgggaagcgg
ttcctggatagtttgcggctgagaatgcacttactggctcattcagcgggtgccaaagcc
tttgtctgtgatcagtgcggtgcacagttttcgaaggaggatgccctggagacacacagg
cagacccatactggcactgacatggccgtcttctgtctgctgtgtgggaagcgcttccag
gcgcagagcgcactgcagcagcacatggaggtccacgcgggcgtgcgcagctacatctgc
agtgagtgcaaccgcaccttccccagccacacggctctcaaacgccacctgcgctcacat
acaggcgaccacccctacgagtgtgagttctgtggcagctgcttccgggatgagagcaca
ctcaagagccacaaacgcatccacacgggtgagaaaccctacgagtgcaatggctgtggc
aagaagttcagcctcaagcatcagctggagacgcactatagggtgcacacaggtgagaag
ccctttgagtgtaagctctgccaccagcgctcccgggactactcggccatgatcaagcac
ctgagaacgcacaacggcgcctcgccctaccagtgcaccatctgcacagagtactgcccc
agcctctcctccatgcagaagcacatgaagggccacaagcccgaggagatcccgcccgac
tggaggatagagaagacgtacctctacctgtgctatgtgtga

Protein Sequence

>7704 : length: 673
MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFE
ILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQCLK
MLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFISKHSSEESGYASVAGQSLPGPM
VDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGTLQPPAGPEEPTLAGGGRHPGVAE
VKTEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGRE
ESAEQVPPPAEAGQAPTGRPEHPAPPPEKHLGIYSVLPNHKADAVLSMPSSVTSGLHVQP
ALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGVELPDNEAVE
QHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHR
QTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSH
TGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEK
PFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPD
WRIEKTYLYLCYV



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