General information | Expression | Regulation | Mutation | Interaction

Basic Information
Gene ID	7704
Name	ZBTB16
Synonymous	PLZF\|ZNF145;zinc finger and BTB domain containing 16;ZBTB16;zinc finger and BTB domain containing 16
Definition	zinc finger and BTB domain-containing protein 16\|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)\|zinc finger protein PLZF
Position	11q23.1
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Transcription Factors

| Top |

Regulation From TransFac database
Cdk1(h) + PLZF(h) <==> PLZF(h):Cdk1(h) (binding)
PLZF(h) + MTG8(h) <==> PLZF(h):MTG8(h) (binding)
p300(h) + PLZF(h) <==> p300(h):PLZF(h) (binding)
PLZF(h) + p/CAF(m.s.) <==> PLZF(h):p/CAF(m.s.) (binding)
PLZF(h) + acetyl-CoA --p300(m.s.)--> CoA + PLZF(h){aceK} (acetylation)
PLZF(h) + acetyl-CoA --p300(h)--> PLZF(h){aceK} + CoA (acetylation)
PLZF(h) + NCOR1(h) <==> PLZF(h):NCOR1(h) (binding)
PLZF(h) + SMRT(h) <==> PLZF(h):SMRT(h) (binding)
HDAC1(m.s.) + PLZF(h) <==> HDAC1(m.s.):PLZF(h) (binding)
PLZF(h) + NCOR1(m) <==> PLZF(h):NCOR1(m) (binding)
PLZF(h) + sumo1(h) --> PLZF(h){sumoK242} (sumoylation)
PLZF(h) + AT2(r) <==> PLZF(h):AT2(r) (binding)
PLZF(h) + VDR(h) <==> VDR(h):PLZF(h) (binding)
PLZF(h) + sin3a(h) <==> PLZF(h):sin3a(h) (binding)
VDR(h) + PLZF(h) <==> VDR(h):PLZF(h) (binding)
MAGE11(h) + PLZF(h) <==> MAGE11(h):PLZF(h) (binding)
PLSCR1(h) + PLZF(h) <==> PLSCR1(h):PLZF(h) (binding)
RFP(h) + PLZF(h) <==> RFP(h):PLZF(h) (binding)
TRAF2(h) + PLZF(h) <==> TRAF2(h):PLZF(h) (binding)
PLZF(h) + SPOP(h) <==> PLZF(h):SPOP(h) (binding)
PLZF(h) + DIPA(h) <==> PLZF(h):DIPA(h) (binding)
PLZF(h) + BCUR1(h) <==> PLZF(h):BCUR1(h) (binding)
PLZF(h) + My012(h) <==> PLZF(h):My012(h) (binding)
PLZF(h) + cNOX(h) <==> PLZF(h):cNOX(h) (binding)
PLZF(h) + cep72(h) <==> PLZF(h):cep72(h) (binding)
PLZF(h) + cep70(h) <==> PLZF(h):cep70(h) (binding)
PLZF(h) + KAP4.12(h) <==> PLZF(h):KAP4.12(h) (binding)
PLZF(h) --> Kit(m) (DNA binding).
PLZF(h) --/ MIRN221(h) (DNA binding; transrepression).
PLZF(h) --/ MIRN222(h) (DNA binding; transrepression).
PLZF(h) --/ ATP6AP2(h) (DNA binding; transrepression).
dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h) + PLZF(h) <==> dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial(h):PLZF(h) (binding)
Trap-2(h) + PLZF(h) <==> Trap-2(h):PLZF(h) (binding)
S9(h) + PLZF(h) <==> S9(h):PLZF(h) (binding)
ZNF-24(h) + PLZF(h) <==> ZNF-24(h):PLZF(h) (binding)
CD81(h) + PLZF(h) <==> CD81(h):PLZF(h) (binding)
platelet-activating factor acetylhydrolase IB subunit gamma(h) + PLZF(h) <==> platelet-activating factor acetylhydrolase IB subunit gamma(h):PLZF(h) (binding)
lyar(h) + PLZF(h) <==> lyar(h):PLZF(h) (binding)
pgam5(h) + PLZF(h) <==> pgam5(h):PLZF(h) (binding)
ZBTB16(h) --> PLZF(h) (expression).
PLZFB(h) --/ HOXB2(m) (DNA binding; transrepression).
PLZFB(h) --/ IL3RA(m) (DNA binding; transrepression).
PLZFB(h) + GATA-2(h) <==> PLZFB(h):GATA-2(h) (binding)
PLZFB(h) + AT2(r) <==> PLZFB(h):AT2(r) (binding)
ZBTB16(h) --> PLZFB(h) (expression).
ZBTB16(h) --> PLZFA(h) (expression).

Post Transcriptional Modification From dbPTM

| Top |

Location (AA)	PTM type	Database
76	Phosphoserine (by PDPK) (Potential).	Swiss-Prot 53.0
184	Phosphoserine (by PDPK) (Potential).	Swiss-Prot 53.0
197	Phosphoserine (by PDPK) (Potential).	Swiss-Prot 53.0
256	Phosphoserine (by PDPK) (Potential).	Swiss-Prot 53.0
282	Phosphothreonine (by PDPK) (Potential).	Swiss-Prot 53.0
628	Phosphoserine (by PDPK) (Potential).	Swiss-Prot 53.0

Methylation Profile From DiseaseMeth database

| Top |

Chromosome	Location	Source
chr11	Promoter: 113434998 - 113436998	Agilent_014791
chr11	Promoter: 113434141 - 113436141	Agilent_014791
chr11	Promoter: 113434141 - 113436141	GSE27584
chr11	Promoter: 113434998 - 113436998	GSE27584
chr11	Promoter: 113434998 - 113436998	Agilent_014791_44K