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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 8031 |
Name | NCOA4 |
Synonym | ARA70|ELE1|PTC3|RFG;nuclear receptor coactivator 4;NCOA4;nuclear receptor coactivator 4 |
Definition | 70 kDa AR-activator|70 kDa androgen receptor coactivator|NCoA-4|RET-activating gene ELE1|androgen receptor-associated protein of 70 kDa|ret fused |
Position | 10q11.2 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | tumor suppressor function of androgen receptor coactivator ARA70alpha in prostate cancer. |
reviewed | ARA70alpha functions as a tumor suppressor gene. |
| More detail of all 1 literatures about NCOA4 | |
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Pathways and Diseases |
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Pathway | Coregulation of Androgen receptor activity;PID Curated;200038 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Thyroid cancer;KEGG PATHWAY;hsa05216 |
Disease | Thyroid cancer;KEGG DISEASE;H00032 |
Disease | Cancers;KEGG DISEASE |
Disease | Thyroid carcinoma, papillary;OMIM |
Disease | Cancers of endocrine organs;KEGG DISEASE |
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External Links |
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Links to Entrez Gene | 8031 |
Links to all GeneRIF Items | 8031 |
Links to iHOP | 8031 |
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Sequence Information |
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Nucleotide Sequence |
>8031 : length: 1953 atgggggcccagttgaccacttttgctctagctggagcagtgaggagaatgaataccttc caagaccagagtggcagctccagtaatagagaaccccttttgaggtgtagtgatgcacgg agggacttggagcttgctattggtggagttctccgggctgaacagcaaattaaagataac ttgcgagaggtcaaagctcagattcacagttgcataagccgtcacctggaatgtcttaga agccgtgaggtatggctgtatgaacaggtggaccttatttatcagcttaaagaggagaca cttcaacagcaggctcagcagctctactcgttattgggccagttcaattgtcttactcat caactggagtgtacccaaaacaaagatctagccaatcaagtctctgtgtgcctggagaga ctgggcagtttgacccttaagcctgaagattcaactgtcctgctctttgaagctgacaca attactctgcgccagaccatcaccacatttgggtctctcaaaaccattcaaattcctgag cacttgatggctcatgctagttcagcaaatattgggcccttcctggagaagagaggctgt atctccatgccagagcagaagtcagcatccggtattgtagctgtccctttcagcgaatgg ctccttggaagcaaacctgccagtggttatcaagctccttacatacccagcaccgacccc caggactggcttacccaaaagcagaccttggagaacagtcagacttcttccagagcctgc aatttcttcaataatgtcgggggaaacctaaagggcttagaaaactggctcctcaagagt gaaaaatcaagttatcaaaagtgtaacagccattccactactagttctttctccattgaa atggaaaaggttggagatcaagagcttcctgatcaagatgagatggacctatcagattgg ctagtgactccccaggaatcccataagctgcggaagcctgagaatggcagtcgtgaaacc agtgagaagtttaagctcttattccagtcctataatgtgaatgattggcttgtcaagact gactcctgtaccaactgtcagggaaaccagcccaaaggtgtggagattgaaaacctgggc aatctgaagtgcctgaatgaccacttggaggccaagaaaccattgtccacccccagcatg gttacagaggattggcttgtccagaaccatcaggacccatgtaaggtagaggaggtgtgc agagccaatgagccctgcacaagctttgcagagtgtgtgtgtgatgagaattgtgagaag gaggctctgtataagtggcttctgaagaaagaaggaaaggataaaaatgggatgcctgtg gaacccaaacctgagcctgagaagcataaagattccctgaatatgtggctctgtcctaga aaagaagtaatagaacaaactaaagcaccaaaggcaatgactccttctagaattgctgat tccttccaagtcataaagaacagccccttgtcggagtggcttatcaggcccccatacaaa gaaggaagtcccaaggaagtgcctggtactgaagacagagctggcaaacagaagtttaaa agccccatgaatacttcctggtgttcctttaacacagctgactgggtcctgccaggaaag aagatgggcaacctcagccagttatcttctggagaagacaagtggctgcttcgaaagaag gcccaggaagtattacttaattcacctctacaggaggaacataacttccccccagaccat tatggcctccctgcagtttgtgatctctttgcctgtatgcagcttaaagttgataaagag aagtggttatatcgaactcctctacaggcatacttcaaaatgaactttcaagatgtaacc gttgggaattttcagatcccatgtggattctag |
Protein Sequence |
>8031 : length: 650 MGAQLTTFALAGAVRRMNTFQDQSGSSSNREPLLRCSDARRDLELAIGGVLRAEQQIKDN LREVKAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQAQQLYSLLGQFNCLTH QLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQTITTFGSLKTIQIPE HLMAHASSANIGPFLEKRGCISMPEQKSASGIVAVPFSEWLLGSKPASGYQAPYIPSTDP QDWLTQKQTLENSQTSSRACNFFNNVGGNLKGLENWLLKSEKSSYQKCNSHSTTSSFSIE MEKVGDQELPDQDEMDLSDWLVTPQESHKLRKPENGSRETSEKFKLLFQSYNVNDWLVKT DSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSTPSMVTEDWLVQNHQDPCKVEEVC RANEPCTSFAECVCDENCEKEALYKWLLKKEGKDKNGMPVEPKPEPEKHKDSLNMWLCPR KEVIEQTKAPKAMTPSRIADSFQVIKNSPLSEWLIRPPYKEGSPKEVPGTEDRAGKQKFK SPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDH YGLPAVCDLFACMQLKVDKEKWLYRTPLQAYFKMNFQDVTVGNFQIPCGF |