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General information | Expression | Regulation | Mutation | Interaction |
Basic Information |
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Gene ID | 8031 |
Name | NCOA4 |
Synonymous | ARA70|ELE1|PTC3|RFG;nuclear receptor coactivator 4;NCOA4;nuclear receptor coactivator 4 |
Definition | 70 kDa AR-activator|70 kDa androgen receptor coactivator|NCoA-4|RET-activating gene ELE1|androgen receptor-associated protein of 70 kDa|ret fused |
Position | 10q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors | | Top | |
Regulation From TransFac database |
5alphaDHT:AR(h) + ARA70(h) <==> 5alphaDHT:AR(h):ARA70(h) (binding) | ARA70(h) + AR(h) <==> AR(h):ARA70(h) (binding) | NCOA4(h) --> ARA70(h) (expression). | AR(h) + ARA70-alpha(h) <==> AR(h):ARA70-alpha(h) (binding) | PPARgamma1(m) + ARA70-alpha(h) <==> PPARgamma1(m):ARA70-alpha(h) (binding) | RXR-alpha(h) + ARA70-alpha(h) <==> RXR-alpha(h):ARA70-alpha(h) (binding) | AR-isoform1(h) + ARA70-alpha(h) <==> AR-isoform1(h):ARA70-alpha(h) (binding) | ARA70-alpha(h) + p/CAF(m.s.) <==> ARA70-alpha(h):p/CAF(m.s.) (binding) | ER-alpha(m) + ARA70-alpha(h) <==> ER-alpha(m):ARA70-alpha(h) (binding) | GR(r) + ARA70-alpha(h) <==> GR(r):ARA70-alpha(h) (binding) | TFIIB(m.s.) + ARA70-alpha(h) <==> TFIIB(m.s.):ARA70-alpha(h) (binding) | NCOA4(h) --> ARA70-alpha(h) (expression). | AR-isoform1(h) + ARA70-beta(h) <==> AR-isoform1(h):ARA70-beta(h) (binding) | ER-alpha(m) + ARA70-beta(h) <==> ER-alpha(m):ARA70-beta(h) (binding) | GR(r) + ARA70-beta(h) <==> GR(r):ARA70-beta(h) (binding) | p/CAF(m.s.) + ARA70-beta(h) <==> p/CAF(m.s.):ARA70-beta(h) (binding) | TFIIB(m.s.) + ARA70-beta(h) <==> TFIIB(m.s.):ARA70-beta(h) (binding) | NCOA4(h) --> ARA70-beta(h) (expression). |
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Post Transcriptional Modification From dbPTM | | Top | |
Location (AA) |
PTM type |
Literature |
Database |
456 | Phosphoserine. | Swiss-Prot 53.0 | 456 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile From DiseaseMeth database | | Top | |
Chromosome |
Location |
Source |
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chr10 |
Promoter: 51240873 - 51242873 | Agilent_014791 |
chr10 |
Promoter: 51240873 - 51242873 | GSE27584 |
chr10 |
Promoter: 51240873 - 51242873 | Agilent_014791_44K |
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